scholarly journals The sense of smell in chronic rhinosinusitis

2020 ◽  
Vol 145 (3) ◽  
pp. 773-776 ◽  
Author(s):  
Joaquim Mullol ◽  
Franklin Mariño-Sánchez ◽  
Meritxell Valls ◽  
Isam Alobid ◽  
Concepció Marin
Keyword(s):  
Chronic Rhinosinusitis ◽  
Sense Of Smell

scholarly journals The sense of smell in chronic rhinosinusitis — literature review

2018 ◽  
Vol 3 (1) ◽  
pp. 1-9
Author(s):  
Łukasz Kluczyński ◽  
Joanna Janiak-Kiszka ◽  
Wojciech Kaźmierczak
Keyword(s):  
Literature Review ◽  
Chronic Rhinosinusitis ◽  
Sense Of Smell

Recovery of Sense of Smell by Mepolizumab in a Patient with Chronic Rhinosinusitis and Nasal Polyposis – A Case Report

2020 ◽  
Vol 01 ◽  
Author(s):  
Mohamed Abuzakouk ◽  
Omar Ghorab ◽  
Safieeldin Ghazala ◽  
Anastasios Hantzakos
Keyword(s):  
Chronic Rhinosinusitis ◽  
Nasal Polyps ◽  
Nasal Polyposis ◽  
Symptom Relief ◽  
Olfactory Dysfunction ◽  
Topical Steroids ◽  
Eosinophilic Asthma ◽  
Sense Of Smell ◽  
Nasal Sprays ◽  
Oral Steroids

Introduction: To date, there is no permanent medical treatment for nasal polyposis and loss of sense of smell. Mepolizumab is an anti-IL-5 monoclonal antibody approved for the treatment of patients with eosinophilic asthma. It has been suggested that it is capable of improving olfactory dysfunction in patients with chronic rhinosinusitis and nasal polyposis. Case: We present a 35-year-old Emirati male with progressively worsening rhinosinusitis, recurring nasal polyps and total loss of sense of smell. He was treated with oral steroids, normal saline nasal sprays and all available topical steroids without significant or permanent symptom relief. He was commenced on Mepolizumab, and upon receiving the 4th dose, he reported full recovery of his sense of smell. Conclusion: Mepolizumab appears to be very effective in treating loss of sense of smell. Further studies should be conducted to assess the efficacy and effectiveness of Mepolizumab in patients with chronic rhinosinusitis, nasal polyposis and anosmia.

Self-Reported Sense of Smell Predicts Disgust Sensitivity and Disgust Reactivity

2018 ◽  
Vol 39 (4) ◽  
pp. 191-195
Author(s):  
Nicholas J. Kelley ◽  
Adrienne L. Crowell
Keyword(s):  
Individual Differences ◽  
Individual Difference ◽  
Olfactory Stimulus ◽  
Disgust Sensitivity ◽  
Sense Of Smell ◽  
Olfactory Ability ◽  
Good Proxy ◽  
Insight Into

Abstract. Two studies tested the hypothesis that self-reported sense of smell (i.e., metacognitive insight into one’s olfactory ability) predicts disgust sensitivity and disgust reactivity. Consistent with our predictions two studies demonstrated that disgust correlates with self-reported sense of smell. Studies 1 and 2 demonstrated, from an individual difference perspective, that trait-like differences in disgust relate to self-reported sense of smell. Physical forms of disgust (i.e., sexual and pathogen disgust) drove this association. However, the association between self-reported sense of smell and disgust sensitivity is small, suggesting that it is likely not a good proxy for disgust sensitivity. The results of Study 2 extended this finding by demonstrating that individual differences in self-reported sense of smell influence how individuals react to a disgusting olfactory stimulus. Those who reported having a better sense of smell (or better insight into their olfactory ability) found a disgusting smell significantly more noxious as compared to participants reporting having a poor sense of smell (or poor insight into their olfactory ability). The current findings suggest that a one-item measure of self-reported sense of smell may be an effective tool in disgust research.

Nasal epithelia cultures of patients with chronic rhinosinusitis show altered ion transport capacities

Pneumologie ◽  
2016 ◽  
Vol 70 (07) ◽  
Author(s):  
JJ Salomon ◽  
T Albrecht ◽  
H Scheuermann ◽  
I Baumann ◽  
MA Mall
Keyword(s):  
Ion Transport ◽  
Chronic Rhinosinusitis
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