scholarly journals Hsa-mir-144-3p expression is increased in umbilical cord serum of infants with atopic dermatitis

2019 ◽  
Vol 143 (1) ◽  
pp. 447-450.e11 ◽  
Author(s):  
Eishika Dissanayake ◽  
Yuzaburo Inoue ◽  
Shingo Ochiai ◽  
Akifumi Eguchi ◽  
Taiji Nakano ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Umbilical Cord ◽  
Cord Serum

Elevated umbilical cord serum TARC/CCL17 levels predict the development of atopic dermatitis in infancy

2010 ◽  
Vol 41 (2) ◽  
pp. 186-191 ◽  
Author(s):  
H. Miyahara ◽  
N. Okazaki ◽  
T. Nagakura ◽  
S. Korematsu ◽  
T. Izumi
Keyword(s):  
Atopic Dermatitis ◽  
Umbilical Cord ◽  
Cord Serum

Gestational Age Dependency of Umbilical Cord Serum IL-6 Levels for Detecting Fetal Inflammation

2020 ◽  
Author(s):  
Sota Iwatani ◽  
Takao Kobayashi ◽  
Sachiko Matsui ◽  
Akihiro Hirata ◽  
Miwa Yamamoto ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Gestational Age ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Significant Negative Correlation ◽  
Cord Serum ◽  
Very Preterm ◽  
Key Points ◽  
Extremely Preterm ◽  
Preterm Newborns

Objective The fetal inflammatory response syndrome (FIRS) is characterized by elevated concentrations of inflammatory cytokines in fetal blood, with preterm delivery and morbidity. Umbilical cord serum interleukin-6 (UC-s-IL-6) is an ideal marker for detecting FIRS. However, the effect of gestational age (GA) on UC-s-IL-6 levels has not been reported. This study aimed to determine the relationship between GA and UC-s-IL-6 levels, and GA-dependent cutoff values of UC-s-IL-6 levels for detecting fetal inflammation. Study Design UC-s-IL-6 concentrations were measured in 194 newborns (44 extremely preterm newborns (EPNs) at 22–27 weeks' GA, 68 very preterm newborns (VPNs) at 28–31 weeks' GA, and 82 preterm newborns (PNs) at 32–34 weeks' GA). Linear regression analyses were used to correlate GA and UC-s-IL-6 levels. Receiver operating characteristic (ROC) curves analyses were performed for detecting the presence of funisitis, as the histopathological counterpart of FIRS. Results A significant negative correlation between GA and UC-s-IL-6 levels was found in newborns with severe funisitis (r s =  − 0.427, p = 0.004) and those with mild funisitis (r s =  − 0.396, p = 0.025). ROC curve analyses revealed the area under the curve for detecting funisitis were 0.856, 0.837, and 0.622 in EPNs, VPNs, and PNs, respectively. The UC-s-IL-6 cutoff value in EPNs (28.1 pg/mL) exceeded those in VPNs and PNs (3.7 and 3.0 pg/mL, respectively). Conclusion UC-s-IL-6 levels were inversely correlated with GA especially in newborns with funisitis. Such GA dependency of UC-s-IL-6 should be considered for detecting fetal inflammation. Key Points

scholarly journals Automated High-Throughput Fatty Acid Analysis of Umbilical Cord Serum and Application to an Epidemiological Study

Lipids ◽  
2012 ◽  
Vol 47 (5) ◽  
pp. 527-539 ◽  
Author(s):  
Yu Hong Lin ◽  
Norman Salem ◽  
Ellen M. Wells ◽  
Weiyin Zhou ◽  
James D. Loewke ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Epidemiological Study ◽  
Umbilical Cord ◽  
High Throughput ◽  
Fatty Acid Analysis ◽  
Cord Serum

scholarly journals INTRAUTERINE GROWTH AND THE VITAMIN E STATUS OF FULL-TERM AND PRETERM NEWBORNS

2019 ◽  
Vol 37 (3) ◽  
pp. 291-296 ◽  
Author(s):  
Alyne Batista da Silva ◽  
Jeane Franco Pires Medeiros ◽  
Mayara Santa Rosa Lima ◽  
Amanda Michelly Braga da Mata ◽  
Eva Débora de Oliveira Andrade ◽  
...  
Keyword(s):  
Vitamin E ◽  
Umbilical Cord ◽  
Gestational Age ◽  
Full Term ◽  
Alpha Tocopherol ◽  
Term Infants ◽  
Intrauterine Growth ◽  
Cord Serum ◽  
Low Levels ◽  
Gestational Age At Birth

ABSTRACT Objective: To determine the concentration of alpha-tocopherol in umbilical cord serum of full-term and preterm newborns, in order to assess the nutritional status of both groups in relation to the vitamin and its possible correlation with intrauterine growth. Methods: A cross-sectional observational study conducted with 140 newborns, of which 64 were preterm and 76 were full-term. They did not have any malformations, they came from healthy mothers, who were nonsmokers, and delivered a single baby. Intrauterine growth was evaluated by weight-to-gestational age at birth, using Intergrowth-21st. Thealpha-tocopherol levels of umbilical cord serum were analyzed by High Performance Liquid Chromatography. Results: The mean concentration of alpha-tocopherol in umbilical cord serum for preterm and full-term infants was 263.3±129.5 and 247.0±147.6 µg/dL (p=0.494). In the preterm group, 23% were small for gestational age, whereas in the full-term group, this percentage was only 7% (p=0.017). Low levels of vitamin E were found in 95.3% of preterm infants and 92.1% of full-term infants. There was no correlation between alpha-tocopherol levels and weight to gestational age Z score (p=0.951). Conclusions: No association was found between alpha-tocopherol levels and weight to gestational age at birth. Intrauterine growth restriction was more frequent in preterm infants and most infants had low levels of vitamin E at the time of delivery.

Umbilical Cord Serum Ionized Magnesium Level and Total Pediatric Mortality

2001 ◽  
Vol 98 (1) ◽  
pp. 75-78
Author(s):  
Robert Mittendorf ◽  
Robert Covert ◽  
Ronald Elin ◽  
Peter G. Pryde ◽  
Babak Khoshnood ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Magnesium Level ◽  
Ionized Magnesium ◽  
Cord Serum

scholarly journals Comparison of three methods for 25-hydroxyvitamin D analysis in umbilical cord serum

2013 ◽  
Vol 72 (OCE3) ◽  
Author(s):  
J. Y. Zhang ◽  
M. Kinsella ◽  
K. Sarafin ◽  
S. P. J. Brooks ◽  
A. J. Lucey ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Cord Serum ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D
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