Analysis of degradation products and structural characterization of giant reed and Chinese silvergrass pretreated by 60Co-γ irradiation

Industrial Crops and Products ◽

10.1016/j.indcrop.2016.01.024 ◽

2016 ◽

Vol 83 ◽

pp. 307-315 ◽

Cited By ~ 9

Author(s):

Qing-ming Li ◽

Xia-jie Li ◽

Yi-le Jiang ◽

Xing-yao Xiong ◽

Qiu-long Hu ◽

...

Keyword(s):

Structural Characterization ◽

Degradation Products ◽

Giant Reed ◽

Γ Irradiation

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Comprehensive degradation profiling and influence of different oxidising reagents on tinoridine hydrochloride: Structural characterization of its degradation products using HPLC and HRMS

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.9210 ◽

2021 ◽

Author(s):

Vivek Dhiman ◽

Kanchan Patil ◽

Laximan Velip ◽

M. V. N. Kumar Talluri ◽

S. Gananadhamu

Keyword(s):

Structural Characterization ◽

Degradation Products

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Isolation and structural characterization of degradation products of afatinib dimaleate by LC-Q-TOF/MS/MS and NMR: cytotoxicity evaluation of afatinib and isolated degradation products

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2019.01.004 ◽

2019 ◽

Vol 166 ◽

pp. 139-146 ◽

Cited By ~ 3

Author(s):

Balasaheb B. Chavan ◽

Vitthal Sawant ◽

Roshan M. Borkar ◽

Srinivas Ragampeta ◽

M.V.N. Kumar Talluri

Keyword(s):

Structural Characterization ◽

Degradation Products ◽

Tof Ms

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Photoluminescence and Structural Characterization of RE‐Doped Sodium Aluminosilicate Oxyfluoride Glass and Nanocrystalline Glass‐Ceramics as a Function of γ‐Irradiation Dose

physica status solidi (b) ◽

10.1002/pssb.201900029 ◽

2019 ◽

Vol 256 (10) ◽

pp. 1900029

Author(s):

Nancy Mahendru ◽

Govind P. Kothiyal ◽

Shivani Singla ◽

Mauro Falconier ◽

Gopi Sharma

Keyword(s):

Structural Characterization ◽

Irradiation Dose ◽

Glass Ceramics ◽

Oxyfluoride Glass ◽

Γ Irradiation ◽

Sodium Aluminosilicate

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Application of online liquid chromatography/quadrupole time‐of‐flight electrospray ionization tandem mass spectrometry for structural characterization of linagliptin degradation products and related impurities

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8874 ◽

2020 ◽

Vol 34 (21) ◽

Author(s):

Amrej Singh Yadav ◽

Divya Dornala ◽

Debasish Swain ◽

Aishwarya Prabha ◽

Gananadhamu Samanthula

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Electrospray Ionization ◽

Structural Characterization ◽

Degradation Products ◽

Time Of Flight ◽

Tandem Mass ◽

Ionization Tandem Mass Spectrometry

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Stability-Indicating RP-UPLC Method Development and Validation for the Process Related Impurities of Nebivolol and Structural Characterization of Its Forced Degradation Products by LC-MS/MS

British Journal of Pharmaceutical Research ◽

10.9734/bjpr/2016/31354 ◽

2016 ◽

Vol 14 (6) ◽

pp. 1-13

Author(s):

Prasad Kancherla ◽

Pallavi Alegete ◽

Srinivas Keesari ◽

Bhavyasri Khagga ◽

Sridhar Siddiraju ◽

...

Keyword(s):

Structural Characterization ◽

Method Development ◽

Degradation Products ◽

Forced Degradation ◽

Stability Indicating ◽

Related Impurities ◽

Method Development And Validation ◽

Development And Validation

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Decision letter for "Application of online liquid chromatography/quadrupole time‐of‐flight electrospray ionization tandem mass spectrometry for structural characterization of Linagliptin degradation products and related impurities"

10.1002/rcm.8874/v2/decision1 ◽

2020 ◽

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Electrospray Ionization ◽

Structural Characterization ◽

Degradation Products ◽

Time Of Flight ◽

Tandem Mass ◽

Ionization Tandem Mass Spectrometry

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Decision letter for "Application of online liquid chromatography/quadrupole time‐of‐flight electrospray ionization tandem mass spectrometry for structural characterization of Linagliptin degradation products and related impurities"

10.1002/rcm.8874/v1/decision1 ◽

2020 ◽

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Electrospray Ionization ◽

Structural Characterization ◽

Degradation Products ◽

Time Of Flight ◽

Tandem Mass ◽

Ionization Tandem Mass Spectrometry

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Glycoblotting-based high throughput protocol for the structural characterization of hyaluronan degradation products during enzymatic fragmentation

Glycoconjugate Journal ◽

10.1007/s10719-012-9395-0 ◽

2012 ◽

Vol 30 (2) ◽

pp. 171-182 ◽

Cited By ~ 5

Author(s):

Takayuki Furukawa ◽

Misaki Arai ◽

Fayna Garcia-Martin ◽

Maho Amano ◽

Hiroshi Hinou ◽

...

Keyword(s):

High Throughput ◽

Structural Characterization ◽

Degradation Products ◽

Enzymatic Fragmentation

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Review for "Application of online liquid chromatography/quadrupole time‐of‐flight electrospray ionization tandem mass spectrometry for structural characterization of Linagliptin degradation products and related impurities"

10.1002/rcm.8874/v1/review1 ◽

2020 ◽

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Electrospray Ionization ◽

Structural Characterization ◽

Degradation Products ◽

Time Of Flight ◽

Tandem Mass ◽

Ionization Tandem Mass Spectrometry

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Identification and structural characterization of four novel degradation products and a process impurity of isavuconazonium sulfate for injection formulation bulk by LC-ESI-QTOF-MS/MS

European Journal of Mass Spectrometry ◽

10.1177/1469066719884402 ◽

2019 ◽

Vol 26 (2) ◽

pp. 144-152

Author(s):

Venkata Rama Prabhakara Sastry Regella ◽

Venkatesan Chidambaram Subramanian ◽

Sarveswara Sastry Bhetanabhotla

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Structural Characterization ◽

Alkaline Hydrolysis ◽

Degradation Products ◽

Water Soluble ◽

Tandem Mass ◽

Light Conditions

Isavuconazonium sulfate is a highly water-soluble pro-drug of active triazole isavuconazole. The degradation profile of isavuconazonium sulfate for injection formulation bulk under acid hydrolysis, alkaline hydrolysis, oxidation, heat, and light conditions was studied using LC-PDA/MS technique. Four degradation products (DP1 to DP4) and one process impurity (PI1) were identified in isavuconazonium sulfate formulation bulk and characterized the identified impurities by liquid chromatography-electron spray ionization-quadruple-time of flight tandem mass spectrometry. Isavuconazole (DP1) was found to be one of the major degradation products of isavuconazonium sulfate.

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