Establishment of monoclonal antibodies against a novel eosinophil-specific cell surface molecule, major facilitator super family domain containing 10

2012 ◽  
Vol 147 (1-2) ◽  
pp. 80-84 ◽  
Author(s):  
Yuji Motoi ◽  
Mayumi Saeki ◽  
Tomoe Nishimura ◽  
Kazufumi Katayama ◽  
Noriko Kitamura ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Specific Cell ◽  
Surface Molecule ◽  
Cell Surface Molecule ◽  
Major Facilitator ◽  
Specific Cell Surface

Monoclonal antibodies to tissue-specific cell surface antigens

1984 ◽  
Vol 33 (2) ◽  
pp. 268-281 ◽  
Author(s):  
Ann M. Carroll ◽  
Michael Zalutsky ◽  
Sam Schatten ◽  
Atul Bhan ◽  
Linda L. Perry ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Surface Antigens ◽  
Specific Cell ◽  
Cell Surface Antigens ◽  
Tissue Specific ◽  
Specific Cell Surface

scholarly journals Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor.

1982 ◽  
Vol 156 (4) ◽  
pp. 1000-1009 ◽  
Author(s):  
D I Beller ◽  
T A Springer ◽  
R D Schreiber
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Polymorphonuclear Leukocytes ◽  
Specific Cell ◽  
Complement Receptor ◽  
Murine Macrophage ◽  
Differentiation Antigen ◽  
Human Macrophages ◽  
Specific Cell Surface

Anti-Mac-1 (M1/70), a rat monoclonal antibody that reacts with mouse and human macrophages, polymorphonuclear leukocytes (PMNL), and natural killer cells, selectively inhibited complement receptor-mediated rosetting by murine macrophages and human PMNL. Preincubation of macrophages with anti-Mac-1 inhibited formation of rosettes with sheep erythrocytes bearing IgM antibody and murine C3 fragments. No inhibition was observed when other monoclonal antibodies that react with macrophages (such as anti-Ly5, anti-H-2, or anti-pan-leukocyte) were tested at 10-fold higher concentrations. Anti-Mac-1 did not affect macrophage Fc receptor-mediated rosetting. Erythrocytes bearing homogeneous human C3 fragments C3b (EC3b) or C3bi (EC3bi) were used to test the specificity of the murine macrophage and human PMNL complement receptor inhibited by anti-Mac-1. In both cases, anti-Mac-1 inhibited CR3-mediated rosetting of EC3bi but not CR1-dependent rosetting of EC3b. The results show that Mac-1 is either identical to CR3 or closely associated with CR3 function. This is one of the first cases in which a monoclonal antibody-defined differentiation antigen has been associated with a specific cell surface function.

Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies

1987 ◽  
Vol 122 (1) ◽  
pp. 90-100 ◽  
Author(s):  
Shin Takagi ◽  
Toshiaki Tsuji ◽  
Takashi Amagai ◽  
Tetsuro Takamatsu ◽  
Hajime Fujisawa
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Xenopus Laevis ◽  
Specific Cell ◽  
Specific Cell Surface ◽  
Xenopus Laevis Tadpole
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