Antibody Cross-Linking of the Thymocyte-Specific Cell Surface Molecule CTX Causes Abnormal Mitosis and Multinucleation of Tumor Cells

1997 ◽  
Vol 235 (1) ◽  
pp. 227-237 ◽  
Author(s):  
Jacques Robert ◽  
Deborah M. Brown ◽  
Louis Du Pasquier ◽  
Nicholas Cohen
2012 ◽  
Vol 147 (1-2) ◽  
pp. 80-84 ◽  
Author(s):  
Yuji Motoi ◽  
Mayumi Saeki ◽  
Tomoe Nishimura ◽  
Kazufumi Katayama ◽  
Noriko Kitamura ◽  
...  

1985 ◽  
Vol 5 (10-11) ◽  
pp. 999-1005 ◽  
Author(s):  
Alan F. Williams ◽  
Albert G.-D. Tse

The Thy-1 glycoprotein is a very abundant cell surface molecule of rat thymocytes and neuronal cells with the properties of a molecule that inserts into the lipid bilayer. The hydrophobicity is due to a glycophospholipid component covalently attached to the carboxy group of the C-terminal cysteine residue. The mature glycoprotein does not contain a stretch of hydrophobic amino acids that could traverse the membrane bilayer. These findings present a new mode of membrane attachment for a cell surface molecule that can mediate lymphokine release and cell division after cross-linking by antibodies.


1992 ◽  
Vol 17 ◽  
pp. 165
Author(s):  
Akihito Mizutani ◽  
Kunimasa Ohta ◽  
Hajime Fujisawa

Nature ◽  
1986 ◽  
Vol 321 (6070) ◽  
pp. 616-618 ◽  
Author(s):  
Max D. Cooper ◽  
David Mulvaney ◽  
Antonio Coutinho ◽  
Pierre-André Cazenave

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