scholarly journals Multiple introductions of MERS-CoV in a 2014 hospital outbreak in Riyadh, Saudi Arabia

2016 ◽  
Vol 45 ◽  
pp. 21
Author(s):  
S. Fagbo ◽  
L. Skakni ◽  
D.K. Chu ◽  
M. Garbati ◽  
M. Peiris ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Multiple Introductions ◽  
Hospital Outbreak

scholarly journals The Phylogeography of MERS-CoV in Hospital Outbreak-Associated Cases Compared to Sporadic Cases in Saudi Arabia

Viruses ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 540
Author(s):  
Xin Chen ◽  
Dillon Charles Adam ◽  
Abrar Ahmad Chughtai ◽  
Sacha Stelzer-Braid ◽  
Matthew Scotch ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Time Frame ◽  
Genome Sequences ◽  
Multiple Introductions ◽  
Multiple Risk Factors ◽  
Hospital Outbreak ◽  
Phylogenetic Methods ◽  
Sporadic Cases ◽  
Evolutionary Speed ◽  
The Impact

This study compared the phylogeography of MERS-CoV between hospital outbreak-associated cases and sporadic cases in Saudi Arabia. We collected complete genome sequences from human samples in Saudi Arabia and data on the multiple risk factors of human MERS-CoV in Saudi Arabia reported from 2012 to 2018. By matching each sequence to human cases, we identified isolates as hospital outbreak-associated cases or sporadic cases. We used Bayesian phylogenetic methods including temporal, discrete trait analysis and phylogeography to uncover transmission routes of MERS-CoV isolates between hospital outbreaks and sporadic cases. Of the 120 sequences collected between 19 June 2012 and 23 January 2017, there were 64 isolates from hospital outbreak-associated cases and 56 from sporadic cases. Overall, MERS-CoV is fast evolving at 7.43 × 10−4 substitutions per site per year. Isolates from hospital outbreaks showed unusually fast evolutionary speed in a shorter time-frame than sporadic cases. Multiple introductions of different MERS-CoV strains occurred in three separate hospital outbreaks. MERS-CoV appears to be mutating in humans. The impact of mutations on viruses transmissibility in humans is unknown.

scholarly journals Molecular Epidemiology of Hospital Outbreak of Middle East Respiratory Syndrome, Riyadh, Saudi Arabia, 2014

2015 ◽  
Vol 21 (11) ◽  
pp. 1981-1988 ◽  
Author(s):  
Shamsudeen F. Fagbo ◽  
Leila Skakni ◽  
Daniel K.W. Chu ◽  
Musa A. Garbati ◽  
Mercy Joseph ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Middle East ◽  
Molecular Epidemiology ◽  
Middle East Respiratory Syndrome ◽  
Hospital Outbreak

scholarly journals Increase in Middle East Respiratory Syndrome-Coronavirus Cases in Saudi Arabia Linked to Hospital Outbreak With Continued Circulation of Recombinant Virus, July 1–August 31, 2015

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
Abdullah M. Assiri ◽  
Holly M. Biggs ◽  
Glen R. Abedi ◽  
Xiaoyan Lu ◽  
Abdulaziz Bin Saeed ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Middle East ◽  
Recombinant Virus ◽  
Healthcare Facility ◽  
Middle East Respiratory Syndrome ◽  
Open Reading Frame ◽  
Viral Sequence ◽  
Reading Frame ◽  
Hospital Outbreak ◽  
Frameshift Deletion

Abstract During July–August 2015, the number of cases of Middle East respiratory syndrome (MERS) reported from Saudi Arabia increased dramatically. We reviewed the 143 confirmed cases from this period and classified each based upon likely transmission source. We found that the surge in cases resulted predominantly (90%) from secondary transmission largely attributable to an outbreak at a single healthcare facility in Riyadh. Genome sequencing of MERS coronavirus from 6 cases demonstrated continued circulation of the recently described recombinant virus. A single unique frameshift deletion in open reading frame 5 was detected in the viral sequence from 1 case.

scholarly journals Multiple Introductions of Dengue 2 Virus Strains into Saudi Arabia from 1992 to 2014

2016 ◽  
Vol 16 (6) ◽  
pp. 391-399 ◽  
Author(s):  
Sherif A. El-Kafrawy ◽  
Sayed S. Sohrab ◽  
Said Abol Ela ◽  
Adly M.M. Abd-Alla ◽  
Rowa Alhabbab ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Multiple Introductions ◽  
Virus Strains

scholarly journals Managing Oncology Services During a Major Coronavirus Outbreak: Lessons From the Saudi Arabia Experience

2020 ◽  
pp. 518-524 ◽  
Author(s):  
Abdul-Rahman Jazieh ◽  
Abdulrahman Al Hadab ◽  
Ashwaq Al Olayan ◽  
Ayman AlHejazi ◽  
Faisal Al Safi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Large Scale ◽  
Health Care Organizations ◽  
Treatment Interruption ◽  
Patients With Cancer ◽  
Hospital Outbreak ◽  
Life Threatening ◽  
Novel Virus ◽  
High Risk Situation ◽  
Life Threatening Event

Outbreaks of infectious etiology, particularly those caused by a novel virus that has no known treatment or vaccine, may result in the interruption of medical care provided to patients with cancer and put them at risk for undertreatment in addition to the risk of being exposed to infection, a life-threatening event among patients with cancer. This article describes the approach used to manage patients with cancer during a large-scale Middle East respiratory syndrome–coronavirus hospital outbreak in Saudi Arabia to ensure continuity of care and minimize harm from treatment interruption or acquiring infection. The approach taken toward managing this high-risk situation (COVID-19) could be easily adopted by health care organizations and would be helpful to ensure readiness for the occurrence of future outbreaks of different infectious etiologies like those recent episodes of new coronavirus.

Confidence toward vaccination as reported by parents of children admitted to a tertiary care hospital in Riyadh, Saudi Arabia: A cross sectional study

Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Abstract #955: Sheehan Syndrome in a Jizan Region of Saudi Arabia.

2016 ◽  
Vol 22 ◽  
pp. 224
Author(s):  
Subodh Banzal ◽  
Sonal Banzal ◽  
Sadhana Banzal ◽  
Ayobenji Ayoola
Keyword(s):  
Saudi Arabia ◽  
Sheehan Syndrome
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