Arginine exposure alters ectonucleotidase activities and morphology of zebrafish larvae ( Danio rerio )

2012 ◽  
Vol 31 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Katiucia Marques Capiotti ◽  
Lidiane Fazenda ◽  
Luiza Reali Nazario ◽  
Fabiano Peres Menezes ◽  
Luiza Wilges Kist ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Zebrafish Larvae

Neurobehavioral effects of bisphenol S exposure in early life stages of zebrafish larvae (Danio rerio)

Chemosphere ◽  
2019 ◽  
Vol 217 ◽  
pp. 629-635 ◽  
Author(s):  
Jie Gu ◽  
Jiayao Zhang ◽  
Yaoyao Chen ◽  
Hongye Wang ◽  
Min Guo ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Early Life ◽  
Life Stages ◽  
Early Life Stages ◽  
Bisphenol S ◽  
Zebrafish Larvae ◽  
Neurobehavioral Effects

Bisphenol F exposure impairs neurodevelopment in zebrafish larvae (Danio rerio)

2020 ◽  
Vol 188 ◽  
pp. 109870 ◽  
Author(s):  
Jie Gu ◽  
Jiang Wu ◽  
Shuqin Xu ◽  
Liye Zhang ◽  
Deling Fan ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Bisphenol F ◽  
Zebrafish Larvae

Toxic effects of indoxacarb enantiomers on the embryonic development and induction of apoptosis in zebrafish larvae (Danio rerio)

2015 ◽  
Vol 32 (1) ◽  
pp. 7-16 ◽  
Author(s):  
Yongmei Fan ◽  
Qing Feng ◽  
Kehua Lai ◽  
Weikang Huang ◽  
Chenghui Zhang ◽  
...  
Keyword(s):  
Embryonic Development ◽  
Danio Rerio ◽  
Toxic Effects ◽  
Zebrafish Larvae ◽  
Induction Of Apoptosis

scholarly journals Fumonisin B1 Production by Fusarium Species and Mycotoxigenic Effect on Larval Zebrafish

2020 ◽  
Vol 31 (3) ◽  
pp. 91-107 ◽  
Author(s):  
Najihah Azman ◽  
Nur Ain Izzati Mohd Zainudin ◽  
Wan Norhamidah Wan Ibrahim
Keyword(s):  
Liquid Chromatography ◽  
Danio Rerio ◽  
Morphological Changes ◽  
Fusarium Species ◽  
Fumonisin B1 ◽  
Larval Zebrafish ◽  
Zebrafish Larvae ◽  
Significant Difference ◽  
Successful Amplification ◽  
Fast Liquid Chromatography

Fumonisin B1 (FB1) is a common mycotoxin produced by Fusarium species particularly F. proliferatum and F. verticillioides. The toxin produced can cause adverse effects on humans and animals. The objectives of this study were to detect the production of FB1 based on the amplification of FUM1 gene, to quantify FB1 produced by the isolates using Ultra-fast Liquid Chromatography (UFLC) analysis, to examine the embryotoxicity effect of FB1 and to determine EC50 toward the larvae of zebrafish (Danio rerio). Fifty isolates of Fusarium species were isolated from different hosts throughout Malaysia. Successful amplification of the FUM1 gene showed the presence of this gene (800 bp) in the genome of 48 out of 50 isolates. The highest level of FB1 produced by F. proliferatum isolate B2433 was 6677.32 ppm meanwhile F. verticillioides isolate J1363 was 954.01 ppm. From the assessment of embryotoxicity test of FB1 on larvae of zebrafish, five concentrations of FB1 (0.43 ppm, 0.58 ppm, 0.72 ppm, 0.87 ppm and 1.00 ppm) were tested. Morphological changes of the FB1 exposed-larvae were observed at 24 to 168 hpf. The mortality rate and abnormality of zebrafish larvae were significantly increased at 144 hpf exposure. Meanwhile, the spontaneous tail coiling showed a significant difference. There were no significant differences in the heartbeat rate. As a conclusion, the presence of FUM1 in every isolate can be detected by FUM1 gene analysis and both of the species produced different concentrations of FB1. This is the first report of FB1 produced by Fusarium species gave a significant effect on zebrafish development.

Recovery Effect of a Rutin-Enriched Fraction Prepared From Forsythia koreana Flowers on Alloxan-Induced Pancreatic Islets in Zebrafish Larvae (Danio rerio)

2021 ◽  
Vol 16 (10) ◽  
pp. 1934578X2110437
Author(s):  
Yeong-Geun Lee ◽  
Youn Hee Nam ◽  
Jung Eun Gwag ◽  
Jung-Hwan Ko ◽  
Kyeong-Hwa Seo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Pancreatic Islets ◽  
Danio Rerio ◽  
Spectroscopic Data ◽  
Recovery Effect ◽  
Meoh Extract ◽  
Simple Method ◽  
Zebrafish Larvae ◽  
Forsythia Koreana ◽  
First Time

A simple method to prepare a high-content rutin fraction from Forsythia koreana flowers (HRFK) is described. Rutin, isolated for the first time from the flowers, was identified from spectroscopic data including nuclear magnetic resonance, mass spectrometry, and infrared. As a result of HPLC quantitative analysis, the content of rutin was found to be 80.0 ± 0.02% in HRFK. Our previous study reported that F koreana MeOH extract (FK) significantly recovered alloxan-induced pancreatic islets in zebrafish. However, HRFK as well as rutin exhibited an enhanced anti-diabetic effect compared to FK in our latest experiments. In conclusion, HRFK, as well as rutin and FK, have potential as anti-diabetic agents.

scholarly journals Influence of Kinship and MHC Class II Genotype on Visual Traits in Zebrafish Larvae (Danio rerio)

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51182 ◽  
Author(s):  
Cornelia Hinz ◽  
Katharina Gebhardt ◽  
Alexander K. Hartmann ◽  
Lauren Sigman ◽  
Gabriele Gerlach
Keyword(s):  
Mhc Class Ii ◽  
Danio Rerio ◽  
Class Ii ◽  
Zebrafish Larvae

scholarly journals Comparison the Effect of Ferutinin and 17β-Estradiol on Bone Mineralization of Developing Zebrafish (Danio rerio) Larvae

2019 ◽  
Vol 20 (6) ◽  
pp. 1507 ◽  
Author(s):  
Hoda Zare Mirakabad ◽  
Mohammad Farsi ◽  
Saeed Malekzadeh Shafaroudi ◽  
Abdolreza Bagheri ◽  
Mehrdad Iranshahi ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Bone Mineralization ◽  
Rt Pcr ◽  
High Concentration ◽  
Treatment Groups ◽  
Time Points ◽  
Zebrafish Larvae ◽  
Similar Expression Pattern ◽  
Novel Drugs ◽  
17Β Estradiol

There is an urgent need to develop novel drugs for osteoporosis which occurs due to estrogen deficiency. Phytoestrogens derived from medicinal plants would be the best alternative to chemical drugs with harmful side effects. The main purpose of the present study was to investigate the effect of ferutinin compared to 17β-estradiol (E2) on bone mineralization of zebrafish larvae. Regarding the lack of publications, the histology analysis was performed after exposure to E2 to find effective treatment on bone mineralization of developing zebrafish larvae. Then, the larvae were exposed to four concentrations of ferutinin at three time points to assess the mortality, the expression of some related genes and histology of the ceratohyal and hyomandibular of treated larvae. The RT-PCR result of the treatment groups demonstrated the similar expression pattern in the larvae which were exposed to 1.25 μg/mL of ferutinin and 2 µM of E2 at 2 dpf, which confirmed the result of histology analysis. In addition, RT-qPCR of high concentration of ferutinin and E2 demonstrated that bmp2a/b and esr1 were downregulated and upregulated when the larvae were exposed to 5 μg/mL of ferutinin and 10 µM of E2, respectively.

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