Effects of Ascophyllum nodosum supplementation on Campylobacter jejuni colonisation, performance and gut health following an experimental challenge in 10day old chicks

2016 ◽  
Vol 37 ◽  
pp. 247-252 ◽  
Author(s):  
T. Sweeney ◽  
H. Meredith ◽  
M.T. Ryan ◽  
V. Gath ◽  
K. Thornton ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Ascophyllum Nodosum ◽  
Gut Health ◽  
Experimental Challenge

scholarly journals Campylobacter jejuni transmission and colonisation in broiler chickens is inhibited by Faecal Microbiota Transplantation

2018 ◽  
Author(s):  
Rachel Gilroy ◽  
Gemma Chaloner ◽  
Amy Wedley ◽  
Lizeth Lacharme-Lora ◽  
Sue Jopson ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Human Infection ◽  
Intestinal Microbiome ◽  
Infection Model ◽  
Rrna Gene ◽  
Broiler Chicks ◽  
Gut Health ◽  
Faecal Microbiota ◽  
Intestinal Colonisation ◽  
Significant Difference

ABSTRACTBACKGROUNDCampylobacter jejuni, the most frequent cause of foodborne bacterial infection, is found on around 70% of retail chicken. As such there is a need for effective controls in chicken production. Microbial-based controls such as probiotics are attractive to the poultry industry, but of limited efficacy. Furthermore, as commercially-produced chickens have no maternal contact, their pioneer microbiome is likely to come from the hatchery environment. Early delivery of microbials that lead to a more ‘natural avian’ microbiome may, therefore, improve bird health and reduce susceptibility to C.jejuni colonisation.A faecal microbiota transplant (FMT) was used to transfer a mature cecal microbiome to newly-hatched broiler chicks and its effects on C.jejuni challenge assessed. We used both a seeder-bird infection model that mimics natural bird-to-bird infection alongside a direct-challenge model. We used a 16S rRNA gene sequencing-based approach to characterize the transplant material itself alongside changes to the chicken microbiome following FMT.RESULTSFMT changes the composition of the chicken intestinal microbiome. We observed little change in species richness following FMT compared to untreated samples, but there is an increase in phylogenetic diversity within those species. The most significant difference in the ceca is an increase in Lactobacilli, although not a major component of the transplant material, suggesting the FMT results in a change in the intestinal milieu as much as a direct change to the microbiome.Upon direct challenge, FMT resulted in lower initial intestinal colonisation with C.jejuni. More significantly, in a seeder-bird challenge of infection transmission, FMT reduced transmission and intestinal colonisation until common UK retail age of slaughter. In a repeat experiment, transmission was completely blocked following FMT treatment. Delayed FMT administration at 7 days of-age had limited effect on colonisation and transmission.CONCLUSIONSWe show that transfer of a whole mature microbiome to newly-hatched chicks reduces transmission and colonisation of C.jejuni. This indicates that modification of the broiler chick microbiome can reduce intestinal colonisation of C.jejuni to levels projected to lead to lower the human infection rate. We believe these findings offer a way to identify key taxa or consortia that are effective in reducing C.jejuni colonisation and improving broiler gut health.

scholarly journals Development of antibiotic resistance and options to replace antimicrobials in animal diets

2001 ◽  
Vol 60 (3) ◽  
pp. 291-299 ◽  
Author(s):  
Knud Erik ◽  
Bach Knudsen
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Infections ◽  
Chemical Properties ◽  
Gut Health ◽  
Growth Promoters ◽  
Eu Member States ◽  
Physico Chemical ◽  
Antimicrobial Growth Promoters ◽  
Experimental Challenge ◽  
The Eu

As there is a risk of developing antibiotic resistance, a number of commonly-used antimicrobial growth promoters have been banned in the EU member states. This decision has put new emphasis on using the diet to control enteric bacterial infections of pigs. Dietary carbohydrates constitute a major proportion of diets for pigs, and the carbohydrate fraction has a diverse composition, with different properties in the gastrointestinal tract, some of which are of importance to gut health. Findings from different studies indicate that dietary carbohydrate composition influences the expression of swine dysentery and infection with nematode worms after experimental challenge withBrachyspira hyodesenteriaeandOesophagostumum dentatumrespectively. In both cases the type, amount and physico-chemical properties of the carbohydrates entering the large intestine played an important role in the infection, and emerging data suggest a synergism between different porcine pathogens. There is also increasing evidence that the feed structure, which relates to the type of plant material in the diet and the way it is processed, can be used to reduceSalmonellaprevalence at the herd level. However, it should be stressed that using the diet to manage gut health is not straightforward, since the expression of a pathogen in many cases requires the presence of other components of the commensal biota.

Ultrastructure of periplasmic bodies in gram-negative bacteria

1990 ◽  
Vol 48 (3) ◽  
pp. 640-641
Author(s):  
Xie Nianming ◽  
Ding Shaoqing ◽  
Wang Luping ◽  
Yuan Zenglin ◽  
Zhan Guolai ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Campylobacter Jejuni ◽  
Proteus Mirabilis ◽  
Shigella Flexneri ◽  
Morphological Description ◽  
Gram Negative Bacteria ◽  
Periplasmic Space ◽  
Clostridium Tetani ◽  
Gram Negative ◽  
Brucella Canis

Perhaps the data about periplasmic enzymes are obtained through biochemical methods but lack of morphological description. We have proved the existence of periplasmic bodies by electron microscope and described their ultrastructures. We hope this report may draw the attention of biochemists and mrophologists to collaborate on researches in periplasmic enzymes or periplasmic bodies with each other.One or more independent bodies may be seen in the periplasmic space between outer and inner membranes of Gram-negative bacteria, which we called periplasmic bodies. The periplasmic bodies have been found in seven species of bacteria at least, including the Pseudomonas aeroginosa. Shigella flexneri, Echerichia coli. Yersinia pestis, Campylobacter jejuni, Proteus mirabilis, Clostridium tetani. Vibrio cholerae and Brucella canis.

Investigations into the antibacterial activities of herbal medicines against Helicobacter pylori and Campylobacter jejuni

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
C Cwikla ◽  
K Schmidt ◽  
A Matthias ◽  
KM Bone ◽  
RP Lehmann ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Campylobacter Jejuni ◽  
Herbal Medicines ◽  
Antibacterial Activities

Anti-adhesive activity of herbal extracts against Campylobacter jejuni

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
K Bensch ◽  
J Tiralongo ◽  
A Matthias ◽  
K Bone ◽  
R Lehmann ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Herbal Extracts

Anti-adhesive activity of extracts from edible and medicinal mushrooms against Campylobacter jejuni

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Chamiolo ◽  
D Oehrke ◽  
K Schmidt ◽  
K Bensch ◽  
J Tiralongo ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Medicinal Mushrooms ◽  
Edible And Medicinal Mushrooms
Sign in / Sign up

Export Citation Format

Share Document