The presence of 12β-deoxydecarbamoylsaxitoxin in the Japanese toxic dinoflagellate Alexandrium determined by simultaneous analysis for paralytic shellfish toxins using HILIC-LC–MS/MS

Harmful Algae ◽  
2015 ◽  
Vol 49 ◽  
pp. 58-67 ◽  
Author(s):  
Yuko Cho ◽  
Shigeki Tsuchiya ◽  
Renpei Yoshioka ◽  
Takuo Omura ◽  
Keiichi Konoki ◽  
...  
1979 ◽  
Vol 36 (1) ◽  
pp. 32-36 ◽  
Author(s):  
C. P. Hsu ◽  
A. Marchand ◽  
Y. Shimizu ◽  
G. G. Sims

The paralytic shellfish poison of the giant sea scallop, Placopecten magellanicus (Gmelin), from the Bay of Fundy has been analyzed. Of eight toxins isolated, seven were identified with those previously recognized in various sources including the Atlantic toxic dinoflagellate, Gonyaulax tamarensis cells. The major components were gonyautoxin-I, gonyautoxin-II, and neosaxitoxin; saxitoxin was responsible for only a very small portion of the total toxicity. A minor toxin that was eluted between neosaxitoxin and saxitoxin in the chromatography system was found to be new and designated as gonyautoxin-VII. Key words: paralytic shellfish poisons, gonyautoxins, neosaxitoxin, Gonyaulax tamarensis


Toxicon ◽  
2008 ◽  
Vol 52 (1) ◽  
pp. 91-100 ◽  
Author(s):  
Carrie J. Donovan ◽  
John C. Ku ◽  
Michael A. Quilliam ◽  
Tom A. Gill

Toxins ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 442
Author(s):  
Seung Ho Baek ◽  
Jung Min Choi ◽  
Minji Lee ◽  
Bum Soo Park ◽  
Yuchengmin Zhang ◽  
...  

Paralytic shellfish toxins (PSTs) produced by Alexandrium catenella (formerly A. tamarense) in Korean coastal waters caused the deaths of four people (in 1986 and 1996) who consumed contaminated mussels (Mytilus edulis). This led to more detailed consideration of the risks of PST outbreaks and incidents in Korea, including the introduction of shellfish collection bans. In this study, we investigated the relationships between A. catenella population dynamics and PST accumulation in the mussel M. galloprovincialis. Discharges from the Nakdong River affect the environmental conditions along the Geoje coast, resulting in low salinity and high nutrient levels that trigger blooms of A. catenella. At the toxin peak on 24 April 2017, the toxins detected in A. catenella cells were C1, gonyautoxin (GTX)1 and GTX2, whereas the concentrations of PSTs in M. galloprovincialis were high and in the order of GTX4 > GTX1 > GTX3 > saxitoxin (STX) > GTX2 > neoSTX > decarbamoylgonyautoxin (dcGTX)2 > dc GTX3. The PST level in mussels was also high. At 15 °C, the PSTs are constantly found to be higher (10-fold higher in 2017 and 30-fold higher in 2018) than safe levels for human consumption (80 μg STX diHCl equivalents 100 g−1).


Toxicon ◽  
1990 ◽  
Vol 28 (6) ◽  
pp. 707-714 ◽  
Author(s):  
Masaaki Kodama ◽  
Takehiko Ogata ◽  
Setsuko Sakamoto ◽  
Shigeru Sato ◽  
Takeshi Honda ◽  
...  

2014 ◽  
Vol 146 ◽  
pp. 205-211 ◽  
Author(s):  
Vanessa M. Lopes ◽  
Miguel Baptista ◽  
Tiago Repolho ◽  
Rui Rosa ◽  
Pedro Reis Costa

Sign in / Sign up

Export Citation Format

Share Document