scholarly journals Uptake kinetics of paralytic shellfish toxins from the dinoflagellate Alexandrium fundyense in the mussel Mytilus edulis

1990 ◽  
Vol 63 ◽  
pp. 177-188 ◽  
Author(s):  
VM Bricelj ◽  
JH Lee ◽  
AD Cembella ◽  
DM Anderson
Keyword(s):  
Mytilus Edulis ◽  
Uptake Kinetics ◽  
Alexandrium Fundyense ◽  
Shellfish Toxins ◽  
Paralytic Shellfish Toxins ◽  
Paralytic Shellfish ◽  
Kinetics Of

Uptake, transfer and elimination kinetics of paralytic shellfish toxins in common octopus (Octopus vulgaris)

2014 ◽  
Vol 146 ◽  
pp. 205-211 ◽  
Author(s):  
Vanessa M. Lopes ◽  
Miguel Baptista ◽  
Tiago Repolho ◽  
Rui Rosa ◽  
Pedro Reis Costa
Keyword(s):  
Octopus Vulgaris ◽  
Elimination Kinetics ◽  
Shellfish Toxins ◽  
Paralytic Shellfish Toxins ◽  
Paralytic Shellfish ◽  
Common Octopus ◽  
Kinetics Of

Uptake, transformation, and elimination kinetics of paralytic shellfish toxins in white seabream (Diplodus sargus)

2011 ◽  
Vol 158 (12) ◽  
pp. 2805-2811 ◽  
Author(s):  
Pedro Reis Costa ◽  
Sandra Lage ◽  
Marisa Barata ◽  
Pedro Pousão-Ferreira
Keyword(s):  
Elimination Kinetics ◽  
Shellfish Toxins ◽  
Paralytic Shellfish Toxins ◽  
Paralytic Shellfish ◽  
Diplodus Sargus ◽  
Kinetics Of

scholarly journals In Vitro Effects of Paralytic Shellfish Toxins and Lytic Extracellular Compounds Produced by Alexandrium Strains on Hemocyte Integrity and Function in Mytilus edulis

Toxins ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 544
Author(s):  
Virginia Angélica Bianchi ◽  
Ulf Bickmeyer ◽  
Urban Tillmann ◽  
Bernd Krock ◽  
Annegret Müller ◽  
...  
Keyword(s):  
Mytilus Edulis ◽  
Phagocytic Activity ◽  
In Vitro Assays ◽  
Shellfish Toxins ◽  
Paralytic Shellfish Toxins ◽  
Paralytic Shellfish ◽  
In Vitro Effects ◽  
Dose Dependent

Harmful effects caused by the exposure to paralytic shellfish toxins (PSTs) and bioactive extracellular compounds (BECs) on bivalves are frequently difficult to attribute to one or the other compound group. We evaluate and compare the distinct effects of PSTs extracted from Alexandrium catenella (Alex5) cells and extracellular lytic compounds (LCs) produced by A. tamarense (NX-57-08) on Mytilus edulis hemocytes. We used a 4 h dose–response in vitro approach and analyzed how these effects correlate with those observed in a previous in vivo feeding assay. Both bioactive compounds caused moderated cell death (10–15%), being dose-dependent for PST-exposed hemocytes. PSTs stimulated phagocytic activity at low doses, with a moderate incidence in lysosomal damage (30–50%) at all tested doses. LCs caused a dose-dependent impairment of phagocytic activity (up to 80%) and damage to lysosomal membranes (up to 90%). PSTs and LCs suppressed cellular ROS production and scavenged H2O2 in in vitro assays. Neither PSTs nor LCs affected the mitochondrial membrane potential in hemocytes. In vitro effects of PST extracts on M. edulis hemocytes were consistent with our previous study on in vivo exposure to PST-producing algae, while for LCs, in vivo and in vitro results were not as consistent.

Bacterial degradation of paralytic shellfish toxins

Toxicon ◽  
2008 ◽  
Vol 52 (1) ◽  
pp. 91-100 ◽  
Author(s):  
Carrie J. Donovan ◽  
John C. Ku ◽  
Michael A. Quilliam ◽  
Tom A. Gill
Keyword(s):  
Bacterial Degradation ◽  
Shellfish Toxins ◽  
Paralytic Shellfish Toxins ◽  
Paralytic Shellfish
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