The determination of possible genetic damage to women undergoing in vitro fertilization due to infertility caused by the male factor

2014 ◽  
Vol 74 ◽  
pp. 294-300 ◽  
Author(s):  
S. Özden ◽  
D. Yüzbaşıoğlu ◽  
F. Ünal ◽  
M. Özel
Keyword(s):  
In Vitro Fertilization ◽  
Genetic Damage ◽  
Male Factor ◽  
Vitro Fertilization

scholarly journals Results and experiences after 1000 IVF cycles at the Clinic for gynecology and obstetrics in Novi Sad

2011 ◽  
Vol 64 (11-12) ◽  
pp. 565-569
Author(s):  
Vesna Kopitovic ◽  
Stevan Milatovic ◽  
Aleksandra Trninic-Pjevic ◽  
Artur Bjelica ◽  
Irena Bujas ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Intracytoplasmic Sperm Injection ◽  
Clinical Pregnancy ◽  
Reproductive Age ◽  
Male Factor ◽  
Fertilization Program ◽  
Vitro Fertilization ◽  
Gynecology And Obstetrics ◽  
Novi Sad

Introduction. Infertility affects 15-17% of reproductive age couples in our country, and 10-15% of couples worldwide. The aim of this paper was to present results and experience gained after the first 1000 cycles of the national In Vitro Fertilization (IVF) program, to offer professional standard of work in our country and to compare it with results obtained in Europe and worldwide. Material and methods. The study prospectively included 1000 women who had undergone national In Vitro Fertilization program from October 2006 until November 2009 at the Department of Gynecology and Obstetrics, Clinical Center of Vojvodina, Novi Sad. Results. The analysis included 1000 in vitro fertilization cycles. Male factor infertility was the leading cause (56.9%) followed by tubal factor (45.9%). The classic method of in vitro fertilization constituted 72.3% of all cycles, while intracytoplasmic sperm injection (ICSI) method was used in 27.7% of all cycles. The average number of embryos transferred was 2.67. The cycle cancellation rate was 14.10% and the aspiration rate was 94.40%. The clinical pregnancy and live birth rate were 33.41% and 26.78% per embryo transfer, respectively. Discussion and conclusion. The results in our study showed that in our setting there are far less intracytoplasmic sperm injection cycles compared with the European average of 66.5% of all fresh cycles, and that we transferred more embryos on average. Our success rates are comparable with those in other European countries where the clinical pregnancy rates per aspiration and per transfer for in vitro fertilization were 29 and 32.4%, respectively in the period of observation. For intracytoplasmic sperm injection, the corresponding rates were 29.9 and 33%.

Kinetic immunonephelometric determination of protein concentrations in follicular fluid.

1987 ◽  
Vol 33 (7) ◽  
pp. 1185-1189 ◽  
Author(s):  
F Gulamali-Majid ◽  
S Ackerman ◽  
L Veeck ◽  
A Acosta ◽  
P Pleban
Keyword(s):  
In Vitro Fertilization ◽  
Follicular Fluid ◽  
Antithrombin Iii ◽  
Oocyte Maturity ◽  
Vitro Fertilization ◽  
Analytical Recovery ◽  
Alpha 1 Antitrypsin ◽  
Respective Protein

Abstract Nonsteroidal biochemical markers of oocyte maturity could presumably aid in oocyte selection and in the timing of insemination for in vitro fertilization. We assessed the usefulness of six potential markers found in follicular fluid. We used kinetic immunonephelometry to measure concentrations of alpha 1-antitrypsin, alpha 2-macroglobulin, antithrombin III, ceruloplasmin, fibrinogen, and plasminogen in 53 fluids and the corresponding plasma from 20 women undergoing in vitro fertilization. Specimens were obtained from both mature and immature follicles from each woman. The respective protein concentrations in follicular fluid could be assayed with a between-assay CV of 1.5% to 3.2%. Analytical-recovery studies indicated that only fibrinogen and antithrombin III concentrations were altered (by 120% and 75%, respectively) during aspiration of the follicle into saline. All protein concentrations were significantly increased in mature follicles, as were the follicular fluid:plasma concentration ratios for alpha 1-antitrypsin, antithrombin III, and ceruloplasmin.

Failure of fertilization in in vitro fertilization: The ?Occult? male factor

1988 ◽  
Vol 5 (4) ◽  
pp. 181-187 ◽  
Author(s):  
Sergio Oehninger ◽  
Anibal A. Acosta ◽  
Thinus Kruger ◽  
Lucinda L. Veeck ◽  
Jill Flood ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Male Factor ◽  
Vitro Fertilization
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