Corrigendum to “Anti-inflammatory activity of hexane extracts from bones and internal organs of Anguilla japonica suppresses cyclooxygenase-2-dependent prostaglandin D2 generation in mast cells and anaphylaxis in mice” [Food Chem. Toxicol. 57 (2013) 307–313]

2014 ◽  
Vol 67 ◽  
pp. 288
Author(s):  
Yue Lu ◽  
Min Kyun Na ◽  
Seok-Jong Suh ◽  
Xian Li ◽  
Geum Jin Kim ◽  
...  
Keyword(s):  
Mast Cells ◽  
Anguilla Japonica ◽  
Cyclooxygenase 2 ◽  
Inflammatory Activity ◽  
Prostaglandin D2 ◽  
Internal Organs ◽  
Hexane Extracts ◽  
Anti Inflammatory

scholarly journals Mast Cells May Regulate The Anti-Inflammatory Activity of IL-37

2019 ◽  
Vol 20 (15) ◽  
pp. 3701 ◽  
Author(s):  
Theoharis C. Theoharides ◽  
Irene Tsilioni ◽  
Pio Conti
Keyword(s):  
Mast Cells ◽  
Immune Cells ◽  
Therapeutic Agents ◽  
Biologically Active ◽  
Inflammatory Activity ◽  
Allergic Reactions ◽  
Regulatory Cytokine ◽  
Inflammatory Processes ◽  
Anti Inflammatory ◽  
Novel Therapeutic

Mast cells are unique immune cells involved in allergic reactions, but also in immunity and inflammation. Interleukin 37 (IL-37) has emerged as an important regulatory cytokine with ability to inhibit immune and inflammatory processes. IL-37 is made primarily by macrophages upon activation of toll-like receptors (TLR) leading to generation of mature IL-37 via the action of caspase 1. In this review, we advance the premise that mast cells could regulate the anti-inflammatory activity of the IL-37 via their secretion of heparin and tryptase. Extracellular IL-37 could either dimerize in the presence of heparin and lose biological activity, or be acted upon by proteases that can generate even more biologically active IL-37 forms. Molecules that could selectively inhibit the secretion of mast cell mediators may, therefore, be used together with IL-37 as novel therapeutic agents.

Anti-inflammatory activity of fisetin in human mast cells (HMC-1)

2007 ◽  
Vol 55 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Hyo-Hyun Park ◽  
Soyoung Lee ◽  
Jae-Min Oh ◽  
Myeung-Su Lee ◽  
Kwon-Ha Yoon ◽  
...  
Keyword(s):  
Mast Cells ◽  
Inflammatory Activity ◽  
Human Mast Cells ◽  
Anti Inflammatory
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