Evaluation of estrogenic activities of hydroxylated polycyclic aromatic hydrocarbons in cigarette smoke condensate

2005 ◽  
Vol 43 (7) ◽  
pp. 1017-1027 ◽  
Author(s):  
Makiko Kamiya ◽  
Akira Toriba ◽  
Yu Onoda ◽  
Ryoichi Kizu ◽  
Kazuichi Hayakawa
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
Cigarette Smoke Condensate ◽  
Polycyclic Aromatic

scholarly journals Determination of Polycyclic Aromatic Hydrocarbons in Cigarettes and Cigarette Smoke

2016 ◽  
Vol 5 (2) ◽  
pp. 15 ◽  
Author(s):  
Haruki Shimazu
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
Experimental Room ◽  
Total Pahs ◽  
Suspended Particulate ◽  
Before And After ◽  
Polycyclic Aromatic ◽  
The Relationship

<p>The present study examines the concentrations of polycyclic aromatic hydrocarbons (PAHs) in cigarettes and sidestream cigarette smoke. Nine PAHs were determined in sidestream cigarette smokes for five types of cigarettes. The volume of the experimental room is approximately 66 m<sup>3</sup>. The air samples in the room were collected before and after smoking. The total PAH concentrations were approximately 1.0 ng/m<sup>3</sup> before smoking, but the median concentration and the range of PAHs were 29.1 ng/m<sup>3</sup> and from 7.62 to 57.6 ng/m<sup>3</sup> after smoking. The relationship between suspended particulate matter (SPM) and total PAHs after smoking is significant and proportional. This may indicate that the SPM formation is associated with PAH formation during smoking. Furthermore, nine PAHs were determined in the cigarettes. Median PAH contents in the five brands of cigarettes ranged from 221 to 936 ng per cigarette before smoking and from 66.9 to 266 ng per cigarette after smoking. Mean PAH emissions from cigarettes while smoking ranged from 257 to 1490 ng per cigarette. The results show that PAHs in the cigarettes, and those generated during smoking, were emitted into the air.</p>

scholarly journals The Composition of Cigarette Smoke. An Historical Perspective of Several Polycyclic Aromatic Hydrocarbons

2009 ◽  
Vol 23 (6) ◽  
pp. 384-410 ◽  
Author(s):  
A Rodgman ◽  
LC Cook
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Melting Point ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
Tobacco Smoke ◽  
Individual Component ◽  
Complex Mixtures ◽  
Polycyclic Aromatic ◽  
The Individual ◽  
Cigarette Mainstream Smoke

AbstractBecause of the significant advancements in fractionation, analytical, and characterization technologies since the early 1960s, hundreds of components of complex mixtures have been accurately characterized without the necessity of actually isolating the individual component. This has been particularly true in the case of the complex mixtures tobacco and tobacco smoke. Herein, an historical account of a mid-1950 situation concerning polycyclic aromatic hydrocarbons (PAHs) in cigarette smoke is presented. While the number of PAHs identified in tobacco smoke has escalated from the initial PAH, azulene, identified in 1947 to almost 100 PAHs identified by late 1963 to more than 500 PAHs identified by the late 1970s, the number of PAHs isolated individually and characterized by several of the so-called classical chemical means (melting point, mixture melting point, derivative preparation and properties) in the mid-1950s and since is relatively few, 14 in all. They were among 44 PAHs identified in cigarette mainstream smoke and included the following PAHs ranging from bicyclic to pentacyclic: Acenaphthylene, 1,2-dihydroacenaphthylene, anthracene, benz[a]anthracene, benzo[a]pyrene, chrysene, dibenz[a, h]anthracene, fluoranthene, 9H-fluorene, naphthalene, 1-methylnaphthalene, 2-methylnaphthalene, phenanthrene, and pyrene. One of them, benzo[a]pyrene, was similarly characterized in another study in 1959 by Hoffmann.

scholarly journals Quantification of Polycyclic Aromatic Hydrocarbons (PAHs) in Cigarette Smoke Particulates by HPLC with Fluorescence Detection

2014 ◽  
Vol 63 (1) ◽  
pp. 23-29
Author(s):  
Akira TORIBA ◽  
Chiharu HONMA ◽  
Waka UOZAKI ◽  
Thanyarat CHUESAARD ◽  
Ning TANG ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Cigarette Smoke ◽  
Fluorescence Detection ◽  
Aromatic Hydrocarbons ◽  
Polycyclic Aromatic

scholarly journals Determination of Polycyclic Aromatic Hydrocarbons In Exhaled Cigarette Smoke

2008 ◽  
Vol 23 (2) ◽  
pp. 85-97 ◽  
Author(s):  
SC Moldoveanu ◽  
W III Coleman ◽  
JM Wilkins
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
High Efficiency ◽  
Solid Phase ◽  
Human Subjects ◽  
New Technique ◽  
Retention Efficiency ◽  
Polycyclic Aromatic ◽  
A New Technique

AbstractThe retention by humans of 20 polycyclic aromatic hydrocarbons (PAHs) from mainstream cigarette smoke was evaluated. The analysis was done by a new technique using solid phase extraction (SPE) for the cleanup and the concenration of PAHs. The new technique has excellent sensitivity and accuracy, which were necessary for the analysis of the very low levels of PAHs present in the exhaled cigarette smoke. The study was done on a common commercial cigarette with 10.6 mg ‘tar’ by U.S. Federal Trade Commission (FTC) recommendation. The results were obtained from ten human subjects, each smoking three cigarettes. The exhaled smoke was collected using a vacuum assisted procedure that avoids strain in exhaling. The study showed that the PAHs with a molecular weight lower than about 170 Daltons are retained with high efficiency. The heavier molecules are less retained, but even compounds such as indeno[1,2,3-cd]pyrene, dibenz[a, h]anthracene, and benzoperylene are retained with efficiencies around 50%. The dependence of retention efficiency for PAHs (in %) on their octanol-water partition coefficient (LogPow) was found to be nonlinear and showed considerable variability for several compounds that have very close LogPow values. Better correlation was obtained between the retention efficiency and PAHs vapor pressure (Log VP).

scholarly journals Analysis of Polycyclic Hydrocarbons

1965 ◽  
Vol 3 (4) ◽  
Author(s):  
E.W. Robb
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Quantitative Analysis ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
Chromatographic Analysis ◽  
Good Precision ◽  
Fluorescence Measurements ◽  
Polycyclic Aromatic ◽  
Chromatographic Procedure ◽  
Paper Chromatographic Separation

AbstractA gas-chromatographic procedure using the electron-capture detector is presented. By fractionation of cigarette smoke on silica gel, followed by gas-chromatographic analysis of the fractions, fifteen polycyclic aromatic hydrocarbons were identified. Application of this procedure to quantitative analysis was demonstrated in the case of benzo[a]pyrene. An analysis for benzo[a]pyrene in cigarette smoke which utilizes paper-chromatographic separation and fluorescence measurements is also presented. This procedure, which gives good precision with a 20-cigarette sample, represents a great simplification of existing methods.

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