Influence of Verapamil and Cyclosporin A on bile acid metabolism and transport in rat liver slices

2006 ◽  
Vol 58 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Astrid Barth ◽  
Jerome Braun ◽  
Dieter Müller
Keyword(s):  
Bile Acid ◽  
Cyclosporin A ◽  
Rat Liver ◽  
Acid Metabolism ◽  
Bile Acid Metabolism ◽  
Liver Slices

scholarly journals Identification of bile acid-CoA: amino acid N-acyltransferase in rat kidney

1991 ◽  
Vol 280 (3) ◽  
pp. 821-824 ◽  
Author(s):  
J B Kwakye ◽  
M R Johnson ◽  
S Barnes ◽  
W E Grizzle ◽  
R B Diasio
Keyword(s):  
Bile Acid ◽  
Amino Acid ◽  
Molecular Mass ◽  
Rat Liver ◽  
Polyclonal Antibody ◽  
Human Liver ◽  
Acid Metabolism ◽  
Rat Kidney ◽  
Immunoblot Analysis ◽  
Bile Acid Metabolism

A novel location of the bile-acid-conjugating enzyme bile acid-CoA:amino acid N-acyltransferase (BAT) has been discovered in the cytosolic fraction of rat kidney. Both taurine and glycine were utilized as substrates. Formation of bile acid N-acyl amidates was verified by h.p.l.c. by comparison with authentic standards and by specific hydrolysis using cholylglycine hydrolase. Immunoblot analysis using a human liver anti-BAT polyclonal antibody indicated that rat kidney BAT has the same molecular mass as rat liver BAT. These findings suggest that the kidney has a role in bile acid metabolism and physiology.

T cell mediated cholangitis alters bile acid metabolism

2018 ◽  
Vol 56 (01) ◽  
pp. E2-E89
Author(s):  
F Glaser ◽  
C John ◽  
B Engel ◽  
B Höh ◽  
S Weidemann ◽  
...  
Keyword(s):  
Bile Acid ◽  
T Cell ◽  
Acid Metabolism ◽  
Bile Acid Metabolism

Combined use of epigallocatechin-3-gallate (EGCG) and caffeine in low doses exhibits marked anti-obesity synergy through regulation of gut microbiota and bile acid metabolism

2021 ◽  
Author(s):  
Ming-zhi Zhu ◽  
Fang Zhou ◽  
Jian Ouyang ◽  
Qi-ye Wang ◽  
Yi-long Li ◽  
...  
Keyword(s):  
Bile Acid ◽  
Synergistic Effect ◽  
Gut Microbiota ◽  
Acid Metabolism ◽  
Bile Acid Metabolism ◽  
Low Doses ◽  
Combined Use

Combined use of epigallocatechin-3-gallate (EGCG) and caffeine in low doses exhibits marked anti-obesity synergy. The synergistic effect may be attributed to regulation of gut microbiota and BA metabolism.

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