Acute effects of air pollution on pediatric asthma exacerbation: Evidence of association and effect modification

2011 ◽  
Vol 111 (3) ◽  
pp. 418-424 ◽  
Author(s):  
E. Samoli ◽  
P.T. Nastos ◽  
A.G. Paliatsos ◽  
K. Katsouyanni ◽  
K.N. Priftis
2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Evangelia Samoli ◽  
Panagiotis Nastos ◽  
Athanasios Paliatsios ◽  
Klea Katsouyanni ◽  
Konstantinos Priftis

Author(s):  
Kari A. Weber ◽  
Wei Yang ◽  
Evan Lyons ◽  
David K. Stevenson ◽  
Amy M. Padula ◽  
...  

To investigate preeclampsia etiologies, we examined relationships between greenspace, air pollution, and neighborhood factors. Data were from hospital records and geocoded residences of 77,406 women in San Joaquin Valley, California from 2000 to 2006. Preeclampsia was divided into mild, severe, or superimposed onto pre-existing hypertension. Greenspace within 100 and 500 m residential buffers was estimated from satellite data using normalized difference vegetation index (NDVI). Air quality data were averaged over pregnancy from daily 24-h averages of nitrogen dioxide, particulate matter <10 µm (PM10) and <2.5 µm (PM2.5), and carbon monoxide. Neighborhood socioeconomic (SES) factors included living below the federal poverty level and median annual income using 2000 US Census data. Odds of preeclampsia were estimated using logistic regression. Effect modification was assessed using Wald tests. More greenspace (500 m) was inversely associated with superimposed preeclampsia (OR = 0.57). High PM2.5 and low SES were associated with mild and severe preeclampsia. We observed differences in associations between greenspace (500 m) and superimposed preeclampsia by neighborhood income and between greenspace (500 m) and severe preeclampsia by PM10, overall and among those living in higher SES neighborhoods. Less greenspace, high particulate matter, and high-poverty/low-income neighborhoods were associated with preeclampsia, and effect modification was observed between these exposures. Further research into exposure combinations and preeclampsia is warranted.


2014 ◽  
Vol 191 ◽  
pp. 139-144 ◽  
Author(s):  
Jing Cai ◽  
Ang Zhao ◽  
Jinzhuo Zhao ◽  
Renjie Chen ◽  
Weibing Wang ◽  
...  

2016 ◽  
Vol 47 (5) ◽  
pp. 1348-1356 ◽  
Author(s):  
Sandrah P. Eckel ◽  
Zilu Zhang ◽  
Rima Habre ◽  
Edward B. Rappaport ◽  
William S. Linn ◽  
...  

Mechanisms for the adverse respiratory effects of traffic-related air pollution (TRAP) have yet to be established. We evaluated the acute effects of TRAP exposure on proximal and distal airway inflammation by relating indoor nitric oxide (NO), a marker of TRAP exposure in the indoor microenvironment, to airway and alveolar sources of exhaled nitric oxide (FeNO).FeNO was collected online at four flow rates in 1635 schoolchildren (aged 12–15 years) in southern California (USA) breathing NO-free air. Indoor NO was sampled hourly and linearly interpolated to the time of the FeNO test. Estimated parameters quantifying airway wall diffusivity (DawNO) and flux (J′awNO) and alveolar concentration (CANO) sources of FeNO were related to exposure using linear regression to adjust for potential confounders.We found that TRAP exposure indoors was associated with elevated alveolar NO. A 10 ppb higher indoor NO concentration at the time of the FeNO test was associated with 0.10 ppb higher average CANO (95% CI 0.04–0.16) (equivalent to a 7.1% increase from the mean), 4.0% higher J′awNO (95% CI −2.8–11.3) and 0.2% lower DawNO (95% CI −4.8–4.6).These findings are consistent with an airway response to TRAP exposure that was most marked in the distal airways.


Author(s):  
Peirong Zhong ◽  
Shichun Huang ◽  
Xiaotong Zhang ◽  
Simin Wu ◽  
Yaohui Zhu ◽  
...  

2021 ◽  
Vol 3 (45) ◽  
pp. 943-947
Author(s):  
Hongtao Niu ◽  
◽  
Tao Yu ◽  
Xuexin Li ◽  
Hanna Wu ◽  
...  

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