Exposure to inorganic arsenic in drinking water and total urinary arsenic concentration in a Chilean population

2005 ◽  
Vol 98 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Dante D. Caceres ◽  
Paulina Pino ◽  
Nestor Montesinos ◽  
Eduardo Atalah ◽  
Hugo Amigo ◽  
...  
Keyword(s):  
Drinking Water ◽  
Arsenic Concentration ◽  
Inorganic Arsenic ◽  
Urinary Arsenic ◽  
Chilean Population

The Arsenic Concentration in Saliva, Urine and Drinking Water in Endemic Arsenicosis Area in Shanyin County of Shanxi Province, China

2011 ◽  
Vol 140 ◽  
pp. 465-468 ◽  
Author(s):  
Da Peng Wang ◽  
San Xiang Wang ◽  
Zheng Hui Wang ◽  
Li Ming Zhang ◽  
Jian Li ◽  
...  
Keyword(s):  
Drinking Water ◽  
Inductively Coupled Plasma ◽  
Arsenic Concentration ◽  
Positive Association ◽  
Shanxi Province ◽  
Atomic Fluorescence Spectrometry ◽  
Arsenic Level ◽  
Significant Positive Association ◽  
Inductively Coupled ◽  
Urinary Arsenic

Biological monitoring for arsenic(As) is usually based upon a determination of urine, blood, nail and hair arsenic concentration, however, saliva has been suggested as a non-invasive biological matrix for assessing exposure. To further evaluate the potential utility of saliva for arsenic biomonitoring, Atomic Fluorescence Spectrometry(AFS-230) and Inductively Coupled Plasma Mass Spectrometer (ICP-MS) were used to evaluate the concentration of arsenic in drinking water, saliva and urine in endemic arsenicosis area in Shanyin County of Shanxi Province. The results showed that the arsenic concentration in drinking water was 0.55-720.0ug/L, and there were 66.67% samples above the arsenic level (50μg/L) of standards for drinking water quality. The median value of arsenic in drinking water was 127.22 μg/L. The salivary and urinary arsenic both can reflect the exposure of arsenic in drinking water. Additionally, there was a significant positive association of salivary arsenic compared with arsenic in drinking water (r=0.674, P<0.05)and urinary arsenic(r=0.794, P<0.05). These results demonstrated that, similar to urinary arsenic, salivary arsenic also can be used as a biomarker for assessing human exposue to arsenic.

Urinary Arsenic Biomonitoring Results In Relation To Inorganic Arsenic In Private Drinking Water Supplies In Cornwall, South West England

2015 ◽  
Vol 2015 (1) ◽  
pp. 3003
Author(s):  
Dan Middleton ◽  
Tony Fletcher ◽  
Michael Watts ◽  
Elliott Hamilton ◽  
Louise Ander ◽  
...  
Keyword(s):  
Drinking Water ◽  
Inorganic Arsenic ◽  
Water Supplies ◽  
Urinary Arsenic ◽  
South West ◽  
South West England

scholarly journals Variation in Arsenic metabolism in schistosomiasis associated bladder pathology in a rural community, Eggua, Ogun State, Nigeria

2021 ◽  
Vol 25 (9) ◽  
pp. 1645-1652
Author(s):  
A.T. Adeboye ◽  
H.O. Awobode ◽  
A.S. Adebayo ◽  
J.R. Djouaka ◽  
R.D. Isokpehi ◽  
...  
Keyword(s):  
Arsenic Concentration ◽  
Arsenic Exposure ◽  
Inorganic Arsenic ◽  
Urogenital Schistosomiasis ◽  
Arsenic Metabolism ◽  
Ogun State ◽  
Specific Pcr ◽  
Urinary Arsenic ◽  
Increased Risk ◽  
Bladder Pathology

Exposure to toxic inorganic Arsenic (iAs) in areas endemic for urogenital schistosomiasis may confer increased risk for bladder cancer. The severity of the adverse effects of iAs however depends on its metabolism, which is highly variable among individuals. Genetic polymorphism in Arsenic (+3) Methyl Transferase enzyme, accounts significantly for these variations. To investigate the relationship of AS3MT gene polymorphisms and Arsenic metabolism to schistosomiasis and/or associated bladder pathology, 119 individualsfrom Eggua in southwest Nigeria were recruited for this study. Screening for schistosomiasis and bladder pathology was done by microscopy and ultrasonography respectively. Wagtech Digital Arsenator was used to assess total urinary arsenic concentrations and thus determine the level of arsenic exposure. The single nucleotide polymorphism AS3MT/Met287Thr T>C (rs11191439) was genotyped using Alelle-Specific PCR. Of the participants who tested positive for schistosomiasis, 33.3% exhibited bladder pathology. Total urinary arsenic concentration in 80% of the participants was above the WHO limit of 0.05mg/L. The Met287Thr allelic distribution conformed to the Hardy-Weinberg equilibrium (X2= 0.161, P> 0.05). Observed allelic frequencies were 0.96 and 0.04 for wild-type T and mutant C alleles respectively. There was no significant relationship between AS3MT SNP, arsenic concentrations and schistosomiasis associated bladder pathology. In conclusion, the community is highly exposed to arsenic, although with a possible genetic advantage of increased AS3MT catalytic activity. However, we see the need for urgent intervention as inter-individual differences in arsenic metabolism may influence the bladder pathology status of individuals in the community. And although urogenital schistosomiasis is waning in Eggua, it is not known what synergy the infection and high arsenic exposure may wield on bladder pathology.

scholarly journals Association between lung cancer risk and inorganic arsenic concentration in drinking water: a dose–response meta-analysis

2018 ◽  
Vol 7 (6) ◽  
pp. 1257-1266 ◽  
Author(s):  
Tanwei Yuan ◽  
Hongbo zhang ◽  
Bin Chen ◽  
Hong Zhang ◽  
Shasha Tao
Keyword(s):  
Lung Cancer ◽  
Drinking Water ◽  
Dose Response ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Arsenic Concentration ◽  
Inorganic Arsenic ◽  
High Dose ◽  
Cancer Risks ◽  
Dose Response Relationship

High dose arsenic in drinking water (≥100 μg L−1) is known to induce lung cancer, but lung cancer risks at low to moderate arsenic levels and its dose–response relationship remains inconclusive.

scholarly journals Effect of Arsenic on Breastfed Baby of Arsenic Affected Lactating Mother

2017 ◽  
Vol 13 (1) ◽  
pp. 99-102
Author(s):  
Ferdousi Hasnat ◽  
Selina Khatun ◽  
Farhana Noman ◽  
Mohammad Ibrahim Khalil ◽  
Nusrat Nahar ◽  
...  
Keyword(s):  
Drinking Water ◽  
Human Milk ◽  
Motor Skills ◽  
Arsenic Concentration ◽  
Armed Forces ◽  
Control Group ◽  
Arsenic Level ◽  
Gross Motor ◽  
Gross Motor Skills ◽  
Urinary Arsenic

Introduction: In the endemic areas of chronic arsenic poisoning of Bangladesh (Cumilla, Noakhali, Laksham, Matlab) drinking water is heavily contaminated with arsenic. An estimated of about 70 million people are at risk from drinking water contaminated with arsenic. There are numerous data on effects of arsenic in adults but a few reports are available on the adverse effect of arsenic on infants and arsenic concentration in human milk, as human milk is the primary source of nutrition during first 6 months of life. Arsenic level found in the urine of infants reflects the intake of arsenic through breast milk. Objective: To find out the effect of arsenic among the breastfed babies of arsenic affected mothers. Materials and Methods: This cross sectional study was conducted in the arsenic exposed area of Bangladesh from January 2007 to July 2008. Thirty exclusively breastfed babies of arsenic affected mothers were enrolled as cases and 30 exclusively breastfed babies from non affected mothers were taken as control. Urinary arsenic concentration was considered for measurement of arsenic status. Mothers with their babies were thoroughly examined for length, weight, occipitofrontal circumference (OFC) and gross motor skills. Results: Arsenic affected mothers excreted high concentration of arsenic (334.68μgm/L±108.02) in their urine than control group (19.17μgm/L±7.92) but the urinary arsenic concentrations from both groups of breast fed babies were found to be low. Growth and development parameters like length, weight, OFC and gross motor skills were also found to be normal in both groups of babies. Conclusion: Exclusive breast feeding should be practiced in arsenic affected area to protect the babies from exposure to arsenic from water sources. Journal of Armed Forces Medical College Bangladesh Vol.13(1) 2017: 99-102

scholarly journals Urinary arsenic profiles reveal exposures to inorganic arsenic from private drinking water supplies in Cornwall, UK

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
D. R. S. Middleton ◽  
M. J. Watts ◽  
E. M. Hamilton ◽  
E. L. Ander ◽  
R. M. Close ◽  
...  
Keyword(s):  
Drinking Water ◽  
Inorganic Arsenic ◽  
Water Supplies ◽  
Urinary Arsenic

Effects of low-level arsenic exposure on urinary N-acetyl-β-D-glucosaminidase activity

2011 ◽  
Vol 30 (12) ◽  
pp. 1885-1891 ◽  
Author(s):  
S-Y Eom ◽  
Y-C Lee ◽  
D-H Yim ◽  
C-H Lee ◽  
Y-D Kim ◽  
...  
Keyword(s):  
Arsenic Concentration ◽  
Arsenic Exposure ◽  
Inorganic Arsenic ◽  
Tubular Damage ◽  
Seafood Consumption ◽  
Arsenic Level ◽  
Urine Sampling ◽  
Low Level ◽  
Urinary Arsenic ◽  
Renal Tubular

This study was aimed to evaluate whether renal tubular function is impaired by exposure to relatively low concentrations of arsenic. Mean urinary arsenic concentrations and N-acetyl-β-d-glucosaminidase (NAG) activities were compared among 365 and 502 Korean men and women, respectively, in relation to gender, smoking, alcohol consumption, and recent seafood consumption. The study subjects were divided into 4 groups according to urinary NAG activity and seafood consumption prior to urine sampling, and the correlation between arsenic concentration and urinary NAG activity was tested for each group. The mean urinary arsenic level was higher in women, non-smokers, and non-drinkers in comparison to men, smokers, and drinkers, respectively. Individuals who consumed seafood within 3 days prior to urine sampling showed a higher mean urinary arsenic level than those who did not. The correlation between urinary arsenic concentration and NAG activity in urine was significant only in subjects who did not consume seafood within 3 days prior to urine sampling and whose urinary NAG activity was 7.44 U/g creatinine (75th percentile) or higher. The urinary arsenic concentration was a significant determinant of urinary NAG activity in subjects with NAG activity higher than 7.44 U/g creatinine and especially in those who had not consumed seafood recently. These facts suggest that a relatively low-level exposure to inorganic arsenic produces renal tubular damage in humans.

scholarly journals Arsenic removal from drinking water using low-pressure nanofiltration under various operating conditions

2018 ◽  
Vol 13 (2) ◽  
pp. 295-302 ◽  
Author(s):  
M. Harfoush ◽  
S. A. Mirbagheri ◽  
M. Ehteshami ◽  
S. Nejati
Keyword(s):  
Drinking Water ◽  
Arsenic Removal ◽  
Arsenic Concentration ◽  
Inorganic Arsenic ◽  
Low Pressure ◽  
Operating Conditions ◽  
Polluted Water ◽  
Initial Concentration ◽  
Wide Range ◽  
Arsenite Removal

Abstract Currently, one of the main environmental concerns is the toxicity caused by arsenic. Arsenic-polluted water can cause many human health problems including various cancerous diseases. In natural water, inorganic arsenic can be found in the forms of arsenite and arsenate, which have been found in several Iranian provinces – e.g., East Azerbaijan, Kurdistan, and the city of Bijar – in high concentrations. Modern nanofiltration (NF) technology enables a wide range of water resource pollutants to be controlled efficiently. In this study, in an attempt to enhance arsenic removal (both arsenite and arsenate) from drinking water using low pressure NF, operating conditions like arsenic concentration, the trans-membrane pressure applied, and a range of different temperatures have all been considered. The highest arsenate removal achieved was 94% with an initial concentration of 500 μg/L, at 7 bar pressure, and 28 °C. The highest arsenite removal was 90%, with an initial concentration of 100 μg/L, at 5 bar pressure, and also at 28 °C. Increasing the pressure had a positive effect on the removal of both species, however, increasing the temperature had negative impacts. It was always found that arsenate removal was better than arsenite removal.

ARSENIC CONCENTRATION VARIABILITY IN NEWLY CONSTRUCTED DRINKING WATER WELLS IN MINNESOTA, USA

2018 ◽  
Author(s):  
Emily Berquist ◽  
◽  
Helen Fitzgerald Malenda ◽  
Melinda L. Erickson
Keyword(s):  
Drinking Water ◽  
Arsenic Concentration ◽  
Water Wells
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