Cardiometabolic traits mediated the relationship from urinary polycyclic aromatic hydrocarbons metabolites to heart rate variability reduction: A community-based study

2018 ◽  
Vol 243 ◽  
pp. 28-36 ◽  
Author(s):  
Yanjun Guo ◽  
Limin Cao ◽  
Yun Zhou ◽  
Lili Xiao ◽  
Xiaomin Zhang ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Community Based ◽  
Polycyclic Aromatic ◽  
The Relationship ◽  
Cardiometabolic Traits

scholarly journals Effects of Personal Exposures to Micro- and Nano-Particulate Matter, Black Carbon, Particle-Bound Polycyclic Aromatic Hydrocarbons, and Carbon Monoxide on Heart Rate Variability in a Panel of Healthy Older Subjects

2019 ◽  
Vol 16 (23) ◽  
pp. 4672 ◽  
Author(s):  
Chin-Sheng Tang ◽  
Kai-Jen Chuang ◽  
Ta-Yuan Chang ◽  
Hsiao-Chi Chuang ◽  
Li-Hsin Chen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Carbon Monoxide ◽  
Heart Rate Variability ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Particulate Matter ◽  
Older People ◽  
Frequency Domain ◽  
Aromatic Hydrocarbons ◽  
Time Domain ◽  
Polycyclic Aromatic

As a non-invasive method, heart rate variability (HRV) has been widely used to study cardiovascular autonomous control. Environmental epidemiological studies indicated that the increase in an average concentration of particulate matter (PM) would result in a decrease in HRV, which was related to the increase of cardiovascular mortality in patients with myocardial infarction and the general population. With rapid economic and social development in Asia, how air pollutants, such as PM of different sizes and their components, affect the cardiovascular health of older people, still need to be further explored. The current study includes a 72 h personal exposure monitoring of seven healthy older people who lived in the Taipei metropolitan area. Mobile equipment, a portable electrocardiogram recorder, and the generalized additive mixed model (GAMM) were adopted to evaluate how HRV indices were affected by size-fractionated PM, particle-bound polycyclic aromatic hydrocarbons (p-PAHs), black carbon (BC), and carbon monoxide (CO). Other related confounding factors, such as age, sex, body mass index (BMI), temperature, relative humidity (RH), time, and monitoring week were controlled by fixed effects of the GAMM. Statistical analyses of multi-pollutant models showed that PM2.5–10, PM1, and nanoparticle (NP) could cause heart rate (HR), time-domain indices, and frequency-domain indices to rise; PM1–2.5 and BC would cause the frequency-domain index to rise; p-PAHs would cause HR to rise, and CO would cause time-domain index and frequency-domain index to decline. In addition, the moving average time all fell after one hour and might appear at 8 h in HRVs’ largest percentage change caused by each pollutant, results of which suggested that size-fractionated PM, p-PAHs, BC, and CO exposures have delayed effects on HRVs. In conclusion, the results of the study showed that the increase in personal pollutant exposure would affect cardiac autonomic control function of healthy older residents in metropolitan areas, and the susceptibility of cardiovascular effects was higher than that of healthy young people. Since the small sample size would limit the generalizability of this study, more studies with larger scale are warranted to better understand the HRV effects of simultaneous PM and other pollution exposures for subpopulation groups.

scholarly journals Exposure to Polycyclic Aromatic Hydrocarbons, Plasma Cytokines and Heart Rate Variability

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Binyao Yang ◽  
Qifei Deng ◽  
Wangzhen Zhang ◽  
Yingying Feng ◽  
Xiayun Dai ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Plasma Cytokines ◽  
Polycyclic Aromatic

scholarly journals Determination of Polycyclic Aromatic Hydrocarbons in Cigarettes and Cigarette Smoke

2016 ◽  
Vol 5 (2) ◽  
pp. 15 ◽  
Author(s):  
Haruki Shimazu
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Cigarette Smoke ◽  
Aromatic Hydrocarbons ◽  
Experimental Room ◽  
Total Pahs ◽  
Suspended Particulate ◽  
Before And After ◽  
Polycyclic Aromatic ◽  
The Relationship

<p>The present study examines the concentrations of polycyclic aromatic hydrocarbons (PAHs) in cigarettes and sidestream cigarette smoke. Nine PAHs were determined in sidestream cigarette smokes for five types of cigarettes. The volume of the experimental room is approximately 66 m<sup>3</sup>. The air samples in the room were collected before and after smoking. The total PAH concentrations were approximately 1.0 ng/m<sup>3</sup> before smoking, but the median concentration and the range of PAHs were 29.1 ng/m<sup>3</sup> and from 7.62 to 57.6 ng/m<sup>3</sup> after smoking. The relationship between suspended particulate matter (SPM) and total PAHs after smoking is significant and proportional. This may indicate that the SPM formation is associated with PAH formation during smoking. Furthermore, nine PAHs were determined in the cigarettes. Median PAH contents in the five brands of cigarettes ranged from 221 to 936 ng per cigarette before smoking and from 66.9 to 266 ng per cigarette after smoking. Mean PAH emissions from cigarettes while smoking ranged from 257 to 1490 ng per cigarette. The results show that PAHs in the cigarettes, and those generated during smoking, were emitted into the air.</p>

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