Amphotericin B ion channel mimetic sensor: A new type of potassium-selective sensor based on electrode-supported hybrid bilayer membranes

2012 ◽  
Vol 73 ◽  
pp. 78-85 ◽  
Author(s):  
Maozeng Yue ◽  
Xin Zhu ◽  
Yanqiong Zheng ◽  
Tao Hu ◽  
Liuming Yang ◽  
...  
Keyword(s):  
Ion Channel ◽  
Amphotericin B ◽  
Bilayer Membranes ◽  
New Type ◽  
Hybrid Bilayer Membranes ◽  
Selective Sensor

Effect of Sterol Side Chain on Ion Channel Formation by Amphotericin B in Lipid Bilayers

Biochemistry ◽  
2014 ◽  
Vol 53 (19) ◽  
pp. 3088-3094 ◽  
Author(s):  
Yasuo Nakagawa ◽  
Yuichi Umegawa ◽  
Tetsuro Takano ◽  
Hiroshi Tsuchikawa ◽  
Nobuaki Matsumori ◽  
...  
Keyword(s):  
Ion Channel ◽  
Amphotericin B ◽  
Lipid Bilayers ◽  
Side Chain ◽  
Channel Formation

Preparation and surface morphology change observation of hybrid bilayer membranes

2006 ◽  
Vol 499 (1-2) ◽  
pp. 40-43 ◽  
Author(s):  
Yasuhiro Nishimura ◽  
Robert Wagner ◽  
Takaaki Manaka ◽  
Mitsumasa Iwamoto
Keyword(s):  
Surface Morphology ◽  
Bilayer Membranes ◽  
Morphology Change ◽  
Hybrid Bilayer Membranes

Planar Phospholipid Membrane Formation in Open Well Thermoplastic Chips

2009 ◽  
Author(s):  
C. Shao ◽  
M. Colombini ◽  
D. L. DeVoe
Keyword(s):  
Ion Channels ◽  
Ion Channel ◽  
Flow Rate ◽  
Channel Measurements ◽  
Phospholipid Membrane ◽  
Membrane Formation ◽  
Bilayer Membranes ◽  
Chamber Volume ◽  
Rapid Perfusion ◽  
Membrane Bound

A key requirement for the effective study of interactions between analytes and ion channels is the ability to dynamically vary analyte type and concentration to a membrane-bound ion channel within a planar phospholipid membrane (PPM). Here an open well microfluidic PPM apparatus supporting dynamic perfusion is presented. The plastic chip supports the manual formation of bilayer membranes that are resistant to pressure disturbances during perfusion with stability on the order of several hours. Using a chamber volume of 20 μL and a flow rate of 0.5 μL/min, the system enables rapid perfusion without breaking the membrane. The perfusion capability is demonstrated through gramicidin ion channel measurements.

Modulation of a gated ion channel admittance in lipid bilayer membranes

1991 ◽  
Vol 6 (5) ◽  
pp. 425-430 ◽  
Author(s):  
David A. Stenger ◽  
David H. Cribbs ◽  
Thomas L. Fare
Keyword(s):  
Ion Channel ◽  
Lipid Bilayer ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes

Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies

2007 ◽  
Vol 48 (19) ◽  
pp. 3393-3396 ◽  
Author(s):  
Yuichi Umegawa ◽  
Nobuaki Matsumori ◽  
Tohru Oishi ◽  
Michio Murata
Keyword(s):  
Ion Channel ◽  
Amphotericin B

Poly(dl-proline), a synthetic polypeptide behaving as an ion channel across bilayer membranes

1985 ◽  
Vol 21 (3-4) ◽  
pp. 211-215 ◽  
Author(s):  
P. De Santis ◽  
A. Palleschi ◽  
M. Savino ◽  
A. Scipioni ◽  
B. Sesta ◽  
...  
Keyword(s):  
Ion Channel ◽  
Bilayer Membranes ◽  
Synthetic Polypeptide
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