scholarly journals Myocardial Injury is More Common than Deep Venous Thrombosis after Vascular Surgery and is Associated with a High One Year Mortality Risk

2018 ◽  
Vol 56 (2) ◽  
pp. 264-270 ◽  
Author(s):  
Jacek Górka ◽  
Kamil Polok ◽  
Jakub Fronczek ◽  
Karolina Górka ◽  
Mateusz Kózka ◽  
...  
Keyword(s):  
Vascular Surgery ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Mortality Risk ◽  
Myocardial Injury ◽  
One Year

Efficacy of compression stockings in preventing post-thrombotic syndrome in patients with deep venous thrombosis: a systematic review and metaanalysis

VASA ◽  
2016 ◽  
Vol 45 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Jakob Martin Burgstaller ◽  
Johann Steurer ◽  
Ulrike Held ◽  
Beatrice Amann-Vesti
Keyword(s):  
Systematic Review ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Cochrane Library ◽  
Compression Stockings ◽  
Post Thrombotic Syndrome ◽  
Study Results ◽  
Preventive Efficacy ◽  
One Year ◽  
The Cochrane Library

Abstract. Background: Here, we update an earlier systematic review on the preventive efficacy of active compression stockings in patients with diagnosed proximal deep venous thrombosis (DVT) by including the results of recently published trials. The aims are to synthesize the results of the original studies, and to identify details to explain heterogeneous results. Methods: We searched the Cochrane Library, PubMed, Scopus, and Medline for original studies that compared the preventive efficacy of active compression stockings with placebo or no compression stockings in patients with diagnosed proximal DVT. Only randomized controlled trials (RCTs) were included. Results: Five eligible RCTs with a total of 1393 patients (sample sizes ranged from 47 to 803 patients) were included. In three RCTs, patients started to wear compression stockings, placebo stockings or no stockings within the first three weeks after the diagnosis of DVT. The results of two RCTs indicate a statistically significant reduction in post-thrombotic syndrome (PTS) of 50% or more after two or more years. The result of one RCT shows no preventive effect of compression stockings at all. Due to the heterogeneity of the study results, we refrained from pooling the results of the RCTs. In a further RCT, randomization to groups with and without compression stockings took place six months after the diagnosis of DVT, and in another RCT, only patients with the absence of PTS one year after the diagnosis of DVT were analyzed. One RCT revealed a significant reduction in symptoms, whereas another RCT failed to show any benefit of using compression stockings. Conclusions: At this time, it does not seem to be justifiable to entirely abandon the recommendations regarding compression stockings to prevent PTS in patients with DVT. There is evidence favoring compression stockings, but there is also evidence showing no benefit of compression stockings.

ID: 47: TESTOSTERONE-HCG THERAPY ASSOCIATED WITH RECURRENT DEEP VENOUS THROMBOSIS-PULMONARY EMBOLISM DESPITE ANTICOAGULATION IN A 55 YEAR OLD MAN WITH THROMBOPHILIA

2016 ◽  
Vol 64 (4) ◽  
pp. 950.3-951
Author(s):  
K Lee ◽  
CJ Glueck
Keyword(s):  
Pulmonary Embolism ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
White Male ◽  
Serum Testosterone ◽  
Normal Serum ◽  
Testosterone Therapy ◽  
Case Presentation ◽  
One Year ◽  
Hcg Therapy

BackgroundWhen exogenous testosterone or treatments to elevate testosterone (human chorionic gonadotropin [HCG] or Clomid) are given to men with underlying familial and/or acquired thrombophilia, deep venous thrombosis and pulmonary embolism often occur, and may recur despite adequate anticoagulation if testosterone therapy is continued.Case PresentationIn a 55 year old white male, referred to us because of 4 thrombotic events, 3 despite adequate anticoagulation over a 5 year period, we assessed interactions between thrombophilia, exogenous testosterone therapy, and recurrent thrombosis. In 2009, despite low-normal serum testosterone 334 ng/dl (lower normal limit [LNL] 300 ng/dl.), he was given testosterone (TT) cypionate (50 mg/week) and HCG (500 units/week) for presumed hypogonadism. Ten months later, with supranormal serum T (1385 ng/dl, UNL 827 ng/dl) and estradiol (E2) 45 pg/ml (UNL 41 pg/ml), he had a pulmonary embolus (PE), and was then anticoagulated for 2 years (enoxaparin, then Coumadin). Four years later, on TT-HCG, he had his first deep venous thrombosis (DVT). TT was stopped, HCG continued; he was anticoagulated (enoxaparin, then Coumadin, then apixaban (Eliquis), then fondaparinux (Arixtra)). One year after his first DVT, on HCG, still on Arixtra, he had a second DVT (5/2015), was anticoagulated (enoxaparin+Coumadin), with a Greenfield filter placed, but 8 days later had a second PE. The Lupus anticoagulant was found to be present. After stopping HCG, and maintained on Coumadin, he has been free of further DVT-PE for 6 months.ConclusionWhen DVT- PE occur on TT or HCG, in the presence of thrombophilia, TT- HCG should be stopped, lest DVT-PE reoccur despite concurrent anticoagulation.

Clinical and anatomical findings of acute iliofemoral deep venous thrombosis

2004 ◽  
Vol 19 (1) ◽  
pp. 42-46 ◽  
Author(s):  
J Saarinen ◽  
M Anturaniemi ◽  
M Heikkinen ◽  
V Suominen ◽  
J-P Salenius
Keyword(s):  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Malignant Disease ◽  
Clinical Findings ◽  
Coagulation Disorder ◽  
Invasive Treatment ◽  
Anatomical Features ◽  
Consecutive Sample ◽  
Post Thrombotic Syndrome ◽  
One Year

Objective: To observe the clinical and anatomical features of acute iliofemoral deep venous thrombosis (DVT). Methods: A consecutive sample of phlebographically confirmed DVT cases during a 25-month period were retrospectively assessed. There were 390 DVT cases, including 73 patients with iliofemoral DVT. The phlebograms of iliofemoral DVTs were reviewed and the location of the thrombus mapped. The patients' files were completely reviewed in all patients with DVT, including concomitant diseases and mortality after the diagnosis of DVT. Results: The average age of the patients with iliofemoral DVT was 63 years compared with 57 years in the cases of infrainguinal DVT ( P<0.005). Left : right-ratio was 2.43 in iliofemoral DVTs, and 1.42 in infrainguinal cases ( P<0.005). Iliofemoral DVT cases were multisegmental (from calf into iliac veins) in 92% of the legs. The aetiology of iliofemoral DVT was idiopathic in 55%, surgery in 14%, malignancy in 14%, immobilization in 10%, trauma in 5%, coagulation disorder in 1% and pregnancy in 1% of the cases. No concomitant diseases were noted in 32% of the patients with iliofemoral DVT, and the corresponding finding in the subgroup of infrainguinal DVTs was 57%. The incidence of death within one-year was 18% and 8% in the subgroups of iliofemoral and infrainguinal DVT. In patients with a combination of iliofemoral DVT and malignancy,the incidence of death within one-year was 80%. Conclusions: According to anatomical findings iliofemoral DVT is typically left-sided and multisegmental. However, clinical findings show that patients with this condition are relatively aged, and the frequency of concomitant diseases is high. The prognosis among the patients with pre-existing malignant disease was very poor. Prevention of post-thrombotic syndrome by using invasive treatment should be considered only in selected cases.

Incidence of Venous Thromboembolism: A Community-based Study in Western France

2000 ◽  
Vol 83 (05) ◽  
pp. 657-660 ◽  
Author(s):  
Emmanuel Oger ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Venous Thromboembolism ◽  
High Risk ◽  
Confidence Interval ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Medical Patients ◽  
Community Based ◽  
Effective Prophylaxis ◽  
One Year

SummaryThe incidence of venous thromboembolism has been studied during one year in a defined population of 342,000 inhabitants. The overall incidence (95% confidence interval) of venous thromboembolism was found to be 1.83 per thousand per year (1.69 to 1.98). The incidences of deep venous thrombosis and pulmonary embolism were 1.24 per thousand per year (1.12 to 1.36) and 0.60 per thousand per year (0.52 to 0.69), respectively. The incidence of venous thromboembolism rose markedly with increasing age for both sexes; over the age of 75, the annual incidence reached 1 per 100. Sixty three percent of the patients were at home when venous thromboembolism occurred. Of these, sixteen percent had been previously hospitalised within three months. These results raise concerns on identification of medical patients at high risk and effective prophylaxis.

scholarly journals Incidence of deep venous thrombosis and stratification of risk groups in a university hospital vascular surgery unit

2015 ◽  
Vol 14 (2) ◽  
pp. 139-144
Author(s):  
Alberto Okuhara ◽  
Túlio Pinho Navarro ◽  
Ricardo Jayme Procópio ◽  
José Oyama Moura de Leite
Keyword(s):  
Deep Vein Thrombosis ◽  
Vascular Surgery ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Risk Groups ◽  
University Hospital ◽  
True Incidence ◽  
Vein Thrombosis ◽  
Deep Vein ◽  
Very High

BACKGROUND: There is a knowledge gap with relation to the true incidence of deep vein thrombosis among patients undergoing vascular surgery procedures in Brazil. This study is designed to support the implementation of a surveillance system to control the quality of venous thromboembolism prophylaxis in our country. Investigations in specific institutions have determined the true incidence of deep vein thrombosis and identified risk groups, to enable measures to be taken to ensure adequate prophylaxis and treatment to prevent the condition.OBJECTIVE: To study the incidence of deep venous thrombosis in patients admitted to hospital for non-venous vascular surgery procedures and stratify them into risk groups.METHOD: This was a cross-sectional observational study that evaluated 202 patients from a university hospital vascular surgery clinic between March 2011 and July 2012. The incidence of deep venous thrombosis was determined using vascular ultrasound examinations and the Caprini scale.RESULTS: The mean incidence of deep venous thrombosis in vascular surgery patients was 8.5%. The frequency distribution of patients by venous thromboembolism risk groups was as follows: 8.4% were considered low risk, 17.3% moderate risk, 29.7% high risk and 44.6% were classified as very high risk.CONCLUSION: The incidence of deep venous thrombosis in vascular surgery patients was 8.5%, which is similar to figures reported in the international literature. Most vascular surgery patients were stratified into the high and very high risk for deep venous thrombosis groups.

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