scholarly journals Screening for Asymptomatic Carotid Plaques with Ultrasound

2016 ◽  
Vol 52 (3) ◽  
pp. 309-312 ◽  
Author(s):  
A.D. Giannoukas ◽  
M. Chabok ◽  
K. Spanos ◽  
A. Nicolaides
1993 ◽  
Vol 80 (10) ◽  
pp. 1274-1277 ◽  
Author(s):  
G. Geroulakos ◽  
G. Ramaswami ◽  
A. Nicolaides ◽  
K. James ◽  
N. Labropoulos ◽  
...  

Vascular ◽  
2021 ◽  
pp. 170853812110609
Author(s):  
Guyue Liu ◽  
Qing Xu ◽  
Min Sun ◽  
Rong Xiao

Aims Hypertension is a major risk factor for coronary, cerebrovascular, and the greatest cause of stroke. Half of stroke events are the result of cerebrovascular atherosclerosis, including carotid plaques. It is of major importance to detect which plaques are vulnerable, even though not yet ruptured. Due to the particularity of the Tibetan population, this study evaluated the elasticity of asymptomatic carotid plaques in Tibetan hypertension patients using shear wave elastography (SWE) and explored associated risk factors. Methods A total of 91 Tibetan patients were divided into normotension, grade 1-2, and grade 3 hypertension groups based on the level of blood pressure. All subjects underwent common duplex ultrasonic examination and SWE evaluation for carotid plaques. Elasticity of carotid plaque was assessed by Young’s modulus. Results The final analysis included 126 plaques as representative plaques according to Total Plaque Risk Score. The mean and maximum Young’s modulus in the grade 3 hypertension group were smaller, and more plaques with irregularity surface compared with the other two groups ( p < 0.05). Multivariate regression analysis showed drinking butter tea (β = −0.220, p = 0.009; β = −0.240, p = 0.004, respectively) was the independent factor associated with mean and maximum Young’s modulus. Conclusions SWE is feasible for measurement of Young’s modulus of carotid plaques. Plaques in the grade 3 hypertension group were more likely to become vulnerable ones. In hypertension Tibetan patients, drinking butter tea was an independent factor associated with mean and maximum Young’s modulus of asymptomatic carotid plaque.


2013 ◽  
Vol 57 (3) ◽  
pp. 609-618.e1 ◽  
Author(s):  
Stavros K. Kakkos ◽  
Maura B. Griffin ◽  
Andrew N. Nicolaides ◽  
Efthyvoulos Kyriacou ◽  
Michael M. Sabetai ◽  
...  

2006 ◽  
Vol 19 (1) ◽  
pp. 205873920601900 ◽  
Author(s):  
R. Sessa ◽  
M. DI Pietro ◽  
G. Schiavoni ◽  
M. Galdiero ◽  
P. Cipriani ◽  
...  

We evaluated, in 415 patients with asymptomatic carotid atherosclerosis: (i) the prevalence of C. pneumoniae DNA in atherosclerotic carotid plaques and peripheral blood mononuclear cells (PBMC); (ii) the distribution of C. pneumoniae in atherosclerotic carotid plaques and PBMC from the same patients; (iii) the correlation between circulating anti-chlamydial antibodies and the presence of C. pneumoniae DNA. Overall, 160 atherosclerotic carotid plaques and 174 PBMC specimens from patients with asymptomatic carotid atherosclerosis were examined by ompA nested touchdown PCR for presence of C. pneumoniae. In addition, C. pneumoniae DNA was detected in 81 specimens of atherosclerotic carotid plaque and PBMC obtained from the same patients. C. pneumoniae DNA was found in 36.9% of atherosclerotic carotid plaques and in 40.2% of PBMC specimens examined (P=NS). With regard to 81 patients, C. pneumoniae DNA was detected in 27.2% of atherosclerotic carotid plaques and in 44.4% of PBMC specimens (P=0.05). In 18 patients, the presence of C. pneumoniae DNA in PBMC specimens and atherosclerotic carotid plaques coincided (P=0.005). No statistically significant association was found between anti-C pneumoniae antibodies (IgG and IgA) and positive PCR results. In conclusion, our results suggest that the detection of C. pneumoniae DNA in PBMC specimens seems to be a first-choice method to identify the patients at risk for endovascular chlamydial infection.


2012 ◽  
Vol 16 (5) ◽  
pp. 966-973 ◽  
Author(s):  
E. C. Kyriacou ◽  
S. Petroudi ◽  
C. S. Pattichis ◽  
M. S. Pattichis ◽  
M. Griffin ◽  
...  

Stroke ◽  
2005 ◽  
Vol 36 (3) ◽  
pp. 525-526 ◽  
Author(s):  
Patrizia Ferroni ◽  
Salvatore Novo ◽  
Valentina Davì ◽  
Giuseppina Novo ◽  
Stefania Basili ◽  
...  

2015 ◽  
Vol 36 (6) ◽  
pp. 499-503 ◽  
Author(s):  
R. Quirce ◽  
I. Martínez-Rodríguez ◽  
I. Banzo ◽  
J. Jiménez-Bonilla ◽  
N. Martínez-Amador ◽  
...  

2011 ◽  
Vol 89 (10) ◽  
pp. 1015-1026 ◽  
Author(s):  
Jani Saksi ◽  
Petra Ijäs ◽  
Krista Nuotio ◽  
Riitta Sonninen ◽  
Lauri Soinne ◽  
...  

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