scholarly journals The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers

2006 ◽  
Vol 31 (3) ◽  
pp. 306-310 ◽  
Author(s):  
B. Mwaura ◽  
B. Mahendran ◽  
N. Hynes ◽  
D. Defreitas ◽  
G. Avalos ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Differential Expression ◽  
Matrix Metalloproteinase 2 ◽  
Leg Ulcers ◽  
Tissue Inhibitor ◽  
Extracellular Matrix Metalloproteinase Inducer ◽  
Venous Leg Ulcers ◽  
The Impact

scholarly journals Differential Expression of Extracellular Matrix Metalloproteinase Inducer (CD147) in Normal and Ulcerated Corneas

2005 ◽  
Vol 166 (1) ◽  
pp. 209-219 ◽  
Author(s):  
Eric E. Gabison ◽  
Samia Mourah ◽  
Emanuelle Steinfels ◽  
Li Yan ◽  
Thanh Hoang-Xuan ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Differential Expression ◽  
Extracellular Matrix Metalloproteinase Inducer

Mitogenic bovine whey extract modulates matrix metalloproteinase-2, -9, and tissue inhibitor of matrix metalloproteinase-2 levels in chronic leg ulcers

2006 ◽  
Vol 14 (1) ◽  
pp. 28-37 ◽  
Author(s):  
Antiopi Varelias ◽  
Allison J. Cowin ◽  
Damian Adams ◽  
Richard H. C. Harries ◽  
Rodney D. Cooter ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Matrix Metalloproteinase 2 ◽  
Leg Ulcers ◽  
Tissue Inhibitor ◽  
Chronic Leg Ulcers

Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer

Tumor Biology ◽  
2007 ◽  
Vol 28 (5) ◽  
pp. 280-289 ◽  
Author(s):  
S. Sillanpää ◽  
M. Anttila ◽  
K. Suhonen ◽  
K. Hämäläinen ◽  
T. Turpeenniemi-Hujanen ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Epithelial Ovarian Cancer ◽  
Prognostic Significance ◽  
Matrix Metalloproteinase 2 ◽  
Extracellular Matrix Metalloproteinase Inducer

scholarly journals Expression of cellular adherent and invasive molecules in recurrent ovarian endometriosis

2020 ◽  
Vol 48 (11) ◽  
pp. 030006052097199
Author(s):  
Tingting Wu ◽  
Rongyan Zhang ◽  
Qiaoying Jiang ◽  
Zhi Li ◽  
Ruijin Wu
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Vascular Endothelial Cells ◽  
Cellular Adhesion ◽  
Matrix Metalloproteinase 2 ◽  
Control Group ◽  
Tissue Inhibitor ◽  
Ovarian Endometriosis ◽  
Recurrent Group ◽  
E Cadherin

Objective This study aimed to examine expression of cellular adhesion molecules and metalloproteinases of the extracellular matrix in ectopic endometrium for evaluating their roles in recurrence of endometriosis. Methods This study retrospectively analyzed 49 female patients (mean age: 30.1±5.5 years) with endometriomas who had undergone two separate operations. After a maximum follow-up of 80 months, all participants were divided into the recurrent group or nonrecurrent (control) group. Samples were immunostained for epithelial cadherin (E-cadherin), β-catenin, urokinase plasminogen activator (uPA), matrix metalloproteinase-9 (MMP-9), tissue inhibitor of matrix metalloproteinase-2, and extracellular matrix metalloproteinase inducer (EMMPRIN). Results In the recurrent group, E-cadherin concentrations in the membrane and cytoplasm of ectopic endometrial glandular cells were significantly reduced, while those of MMP-9 and EMMPRIN were higher than those in the control group. Additionally, uPA concentrations in the membrane and cytoplasm of ectopic endometrial glandular, stromal, and vascular endothelial cells were significantly higher in the recurrent group than in the control group. Tissue inhibitor of matrix metalloproteinase-2 and β-catenin concentrations were similar between the groups. Conclusion E-cadherin, MMP-9, and associated factors may contribute to development of endometriosis. E-cadherin, MMP-9, and uPA may act as potential markers for detection of recurrence of endometriosis.

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