Inhibition of sulfur compounds and antioxidants on MMP-2 and -9 at the activity level found during neonatal hypoxia–reoxygenation

2006 ◽  
Vol 544 (1-3) ◽  
pp. 168-173 ◽  
Author(s):  
Marwan Emara ◽  
Po-Yin Cheung
Keyword(s):  
Sulfur Compounds ◽  
Activity Level ◽  
Neonatal Hypoxia ◽  
Hypoxia Reoxygenation

scholarly journals PS-159 Beta-amyloid And S100b Could Be Valuable Biomarkers After Neonatal Hypoxia-reoxygenation. A Study In Newborn Pigs

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A168.2-A168
Author(s):  
T Benterud ◽  
L Pankratov ◽  
R Solberg ◽  
OD Saugstad ◽  
A Skinningsrud ◽  
...  
Keyword(s):  
Beta Amyloid ◽  
Neonatal Hypoxia ◽  
Newborn Pigs ◽  
Hypoxia Reoxygenation

Doxycycline Attenuates Renal Injury In A Swine Model Of Neonatal Hypoxia-Reoxygenation

Shock ◽  
2015 ◽  
Vol 43 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Joseph R. Labossiere ◽  
Jean-Sebastian Pelletier ◽  
Aducio Thiesen ◽  
Richard Schulz ◽  
David L. Bigam ◽  
...  
Keyword(s):  
Renal Injury ◽  
Swine Model ◽  
Neonatal Hypoxia ◽  
Hypoxia Reoxygenation

Differential Hemodynamic Effects of Levosimendan in a Porcine Model of Neonatal Hypoxia-Reoxygenation

Neonatology ◽  
2012 ◽  
Vol 101 (3) ◽  
pp. 192-200 ◽  
Author(s):  
J. Esch ◽  
C. Joynt ◽  
N. Manouchehri ◽  
T.F. Lee ◽  
Y.-Q. Li ◽  
...  
Keyword(s):  
Porcine Model ◽  
Hemodynamic Effects ◽  
Neonatal Hypoxia ◽  
Hypoxia Reoxygenation

scholarly journals 86 Low-Dose Vasopressin is Cardioprotective in an Acute Swine Model of Neonatal Hypoxia-Reoxygenation

2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A24-A24
Author(s):  
J. Pelletier ◽  
J. LaBossiere ◽  
R. Gill ◽  
C. Sergi ◽  
D. Bigam ◽  
...  
Keyword(s):  
Low Dose ◽  
Swine Model ◽  
Neonatal Hypoxia ◽  
Hypoxia Reoxygenation

Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

2020 ◽  
Vol 64 (2) ◽  
pp. 325-336 ◽  
Author(s):  
Dimitriya H. Garvanska ◽  
Jakob Nilsson
Keyword(s):  
Spindle Assembly Checkpoint ◽  
Activity Level ◽  
Phosphorylation Sites ◽  
Binding Affinities ◽  
Mitotic Kinases ◽  
Anaphase Onset ◽  
Phosphoprotein Phosphatases ◽  
Linear Motifs ◽  
Temporal And Spatial ◽  
Kinetochore Function

Abstract Kinetochores are instrumental for accurate chromosome segregation by binding to microtubules in order to move chromosomes and by delaying anaphase onset through the spindle assembly checkpoint (SAC). Dynamic phosphorylation of kinetochore components is key to control these activities and is tightly regulated by temporal and spatial recruitment of kinases and phosphoprotein phosphatases (PPPs). Here we focus on PP1, PP2A-B56 and PP2A-B55, three PPPs that are important regulators of mitosis. Despite the fact that these PPPs share a very similar active site, they target unique ser/thr phosphorylation sites to control kinetochore function. Specificity is in part achieved by PPPs binding to short linear motifs (SLiMs) that guide their substrate specificity. SLiMs bind to conserved pockets on PPPs and are degenerate in nature, giving rise to a range of binding affinities. These SLiMs control the assembly of numerous substrate specifying complexes and their position and binding strength allow PPPs to target specific phosphorylation sites. In addition, the activity of PPPs is regulated by mitotic kinases and inhibitors, either directly at the activity level or through affecting PPP–SLiM interactions. Here, we discuss recent progress in understanding the regulation of PPP specificity and activity and how this controls kinetochore biology.

Hypoxia/Reoxygenation on human myometrial and decidual cells: A molecular mechanism involved in preterra labor

1998 ◽  
Vol 5 (1) ◽  
pp. 187A-187A
Author(s):  
J CARVAJAL ◽  
S KATO ◽  
J SAEZ ◽  
F LEIGHTON ◽  
G VALENZUELA ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Decidual Cells ◽  
Hypoxia Reoxygenation

Self-Referent Thoughts in Exercise: The Self-Perception in Exercise Questionnaire

1997 ◽  
Vol 13 (3) ◽  
pp. 195-205 ◽  
Author(s):  
Marit Sorensen
Keyword(s):  
Physical Activity ◽  
Pilot Study ◽  
Physical Activity Level ◽  
Convergent Validity ◽  
English Language ◽  
Lifestyle Changes ◽  
Activity Level ◽  
Language Version ◽  
Social Comfort ◽  
And Gender

Adherence to lifestyle changes - beginning to exercise, for example - is assumed to be mediated by self-referent thoughts. This paper describes a pilot study and three studies conducted to develop and validate a questionnaire for adults to determine their self-perceptions related to health-oriented exercise. The pilot study identified items pertinent to the domains considered important in this context, and began the process of selecting items. Study 2 examined the factor structure, reduced the number of items, determined the internal consistency of the factors, and explored the discriminative validity of the questionnaire as to physical activity level and gender. Four factors with a total of 24 items were accepted, measuring mastery of exercise, body perception, social comfort/discomfort in the exercise setting, and perception of fitness. All subscales had acceptable internal consistencies. Preliminary validity was demonstrated by confirming hypothesized differences in scores as to gender, age, and physical activity level. The third study examined and demonstrated convergent validity with similar existing subscales. The fourth study examined an English-language version of the questionnaire, confirming the existence of the factors and providing preliminary psychometric evidence of the viability of the questionnaire.

Sign in / Sign up

Export Citation Format

Share Document