Permeability of the reconstructed human epidermis model Episkin® in comparison to various human skin preparations☆

2007 ◽  
Vol 66 (1) ◽  
pp. 127-134 ◽  
Author(s):  
Frank Netzlaff ◽  
Monika Kaca ◽  
Udo Bock ◽  
Eleonore Haltner-Ukomadu ◽  
Peter Meiers ◽  
...  
Author(s):  
A. P. Lupulescu ◽  
H. Pinkus ◽  
D. J. Birmingham

Our laboratory is engaged in the study of the effect of different chemical agents on human skin, using electron microscopy. Previous investigations revealed that topical use of a strong alkali (NaOH 1N) or acid (HCl 1N), induces ultrastructural changes in the upper layers of human epidermis. In the current experiments, acetone and kerosene, which are primarily lipid solvents, were topically used on the volar surface of the forearm of Caucasian and Negro volunteers. Skin specimens were bioptically removed after 90 min. exposure and 72. hours later, fixed in 3% buffered glutaraldehyde, postfixed in 1% phosphate osmium tetroxide, then flat embedded in Epon.


2018 ◽  
Vol 6 (1) ◽  
pp. 64 ◽  
Author(s):  
Rodrigo De Vecchi ◽  
Vanja Dakic ◽  
Guilherme Mattos ◽  
Anne-Sophie Rigaudeau ◽  
Veronica Oliveira ◽  
...  

Mycoses ◽  
2019 ◽  
Vol 62 (12) ◽  
pp. 1194-1201 ◽  
Author(s):  
Ana Filipa Pedrosa ◽  
Carmen Lisboa ◽  
Joana Branco ◽  
Ana C. Almeida ◽  
Claudia Mendes ◽  
...  

2013 ◽  
Vol 65 ◽  
pp. S128
Author(s):  
Jeremie Soeur ◽  
Laurent Marrot ◽  
Joan Eilstein ◽  
Christophe Jones ◽  
Guillaume Lereaux ◽  
...  

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