ERCC3, a new ovarian cancer susceptibility gene?

2020 ◽  
Vol 141 ◽  
pp. 1-8
Author(s):  
Agostina Stradella ◽  
Jesús del Valle ◽  
Paula Rofes ◽  
Gardenia Vargas-Parra ◽  
Mónica Salinas ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Susceptibility ◽  
Susceptibility Gene ◽  
Cancer Susceptibility Gene

BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28

2016 ◽  
Vol 473 (7) ◽  
pp. 949-960 ◽  
Author(s):  
Anne Vincent ◽  
Elise Berthel ◽  
Estelle Dacheux ◽  
Clémence Magnard ◽  
Nicole L. Dalla Venezia
Keyword(s):  
Ovarian Cancer ◽  
Protein Phosphatase ◽  
Cancer Susceptibility ◽  
Susceptibility Gene ◽  
Ankyrin Repeat ◽  
Regulatory Subunit ◽  
Breast And Ovarian Cancer ◽  
Repeat Domain ◽  
Ankyrin Repeat Domain ◽  
Cancer Susceptibility Gene

We report a novel interaction between the tumour suppressor BRCA1 (breast and ovarian cancer-susceptibility gene 1) and the PP6 (protein phosphatase 6) regulatory subunit ANKRD28 (ankyrin repeat domain 28) in the cytoplasm, and further identify BRCA1 as a novel modulator of PP6.

Sign in / Sign up

Export Citation Format

Share Document