Myocardial Strain and Strain Rate from Speckle-Tracking Echocardiography are Unable to Differentiate Asymptomatic Biopsy-Proven Cellular Rejection in the First Year after Cardiac Transplantation

2015 ◽  
Vol 28 (4) ◽  
pp. 478-485 ◽  
Author(s):  
Amrut V. Ambardekar ◽  
Nitya Alluri ◽  
Amit C. Patel ◽  
JoAnn Lindenfeld ◽  
Jennifer L. Dorosz
Keyword(s):  
Strain Rate ◽  
Speckle Tracking ◽  
Cardiac Transplantation ◽  
Speckle Tracking Echocardiography ◽  
Myocardial Strain ◽  
First Year ◽  
Strain And Strain Rate ◽  
Cellular Rejection

scholarly journals Transverse Right Ventricle Strain and Strain Rate Assessed by 2-Dimensional Speckle Tracking Echocardiography in Dogs with Pulmonary Hypertension

2020 ◽  
Vol 7 (1) ◽  
pp. 19 ◽  
Author(s):  
Domenico Caivano ◽  
Mark Rishniw ◽  
Francesco Birettoni ◽  
Vasilica-Flory Petrescu ◽  
Francesco Porciello
Keyword(s):  
Pulmonary Hypertension ◽  
Right Ventricle ◽  
Strain Rate ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Radial Strain ◽  
Transverse Strain ◽  
Strain Component ◽  
Strain And Strain Rate ◽  
Healthy Dogs

Right ventricular (RV) strain analysis using 2-dimensional speckle tracking echocardiography (2D STE) permits practitioners to assess regional and global deformation of the myocardium. Recently, assessment of the longitudinal right ventricle (RV) strain and strain rate using 2D STE has been reported in dogs. Although longitudinal deformation is the dominant component of the RV systole, RV myocardial fibers of the superficial layer are oriented circumferentially and these contribute to the RV pump function (radial deformation). Because this strain component has not been investigated in dogs, we have assessed radial RV strain and strain rate using 2D STE in healthy dogs and dogs with pulmonary hypertension (PH). We have recruited 74 dogs (40 healthy dogs and 34 dogs with PH) in which we have analyzed radial RV free wall strain and strain rate using XstrainTM software. We have used the left apical 4-chamber view optimized for the RV for analysis of the radial strain and strain rate variables (XstrainTM software denoted radial strain as “transverse”). Seven dogs were excluded during the analysis for low quality images. Transverse strain and strain rate obtained in healthy dogs showed no relationship with heart rate, body weight or age (r2 < 0.09 and p > 0.05 for all variables). Moreover, no relationship between transverse strain/strain rate variables and left atrial-to-aortic ratios was observed (r2 < 0.06 and p = 0.2, for both). Transverse strain and strain rate obtained in dogs with PH, showed weak negative relationships with tricuspid regurgitation velocity (r2 < 0.25 and p = 0.006, for both). Transverse RV strain and strain rate using 2D STE is feasible in most dogs and decrease with worsening of the PH, but these advanced echocardiographic indices do not help in identifying dogs with PH.

scholarly journals Myocardial Strain Imaging Using Two and Three-Dimensional Speckle Tracking Echocardiography: Clinical Applications

2019 ◽  
Vol 11 (2) ◽  
pp. 167-182
Author(s):  
Tuhin Haque
Keyword(s):  
Strain Rate ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Function Analysis ◽  
Myocardial Strain ◽  
Three Dimensional ◽  
Severe Heart Failure ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
2D Strain

Cardiac function analysis is the main focus of echocardiography. Myocardial strain & strain rate imaging have emerged as a quantitative technique to accurately estimate myocardial function. In the last decade, two dimensional speckle tracking echocardiography (2DSTE) has gained popularity as a novel technique for strain & strain rate measurement. This technique has been found clinically useful in the assessment of cardiac systolic & diastolic function. 2D strain could potentially be used to differentiate disease from nondisease segments, for identifying early subclinical changes in various pathologies and to learn more about the various strain patterns indicative of specific disease types. A large number of studies have evaluated the role of 2DSTE in predicting the response to cardiac resynchronization therapy in patients with severe heart failure. Emerging areas of applications of 2DSTE include prediction of rejection in heart transplant patients, early detection of cardiotoxicity in patients receiving chemotherapy for cancer and effect of intracoronary injection of bone marrow stem cells on left ventricular function in patients with acute myocardial infarction. However, 2D imaging methods have limitations in assessing three dimensional (3D) cardiac motion. Experimental studies and clinical investigations revealed the reliability and feasibility of 3DSTE-derived data. In this review, the methodology, validation, and clinical application of both 2D &3DSTE have been discussed. Cardiovasc. j. 2019; 11(2): 167-182

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