Strain and strain rate echocardiography variables in adult Wilson's disease patients: A speckle tracking echocardiography study

2020 ◽  
Vol 48 (6) ◽  
pp. 324-329
Author(s):  
Süleyman Cagan EFE ◽  
Ahmet Seyfettin Gurbuz ◽  
Semi Ozturk ◽  
Kadir Demir
Keyword(s):  
Strain Rate ◽  
Speckle Tracking ◽  
Wilson’S Disease ◽  
Speckle Tracking Echocardiography ◽  
Wilson's Disease ◽  
Strain And Strain Rate

scholarly journals Transverse Right Ventricle Strain and Strain Rate Assessed by 2-Dimensional Speckle Tracking Echocardiography in Dogs with Pulmonary Hypertension

2020 ◽  
Vol 7 (1) ◽  
pp. 19 ◽  
Author(s):  
Domenico Caivano ◽  
Mark Rishniw ◽  
Francesco Birettoni ◽  
Vasilica-Flory Petrescu ◽  
Francesco Porciello
Keyword(s):  
Pulmonary Hypertension ◽  
Right Ventricle ◽  
Strain Rate ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Radial Strain ◽  
Transverse Strain ◽  
Strain Component ◽  
Strain And Strain Rate ◽  
Healthy Dogs

Right ventricular (RV) strain analysis using 2-dimensional speckle tracking echocardiography (2D STE) permits practitioners to assess regional and global deformation of the myocardium. Recently, assessment of the longitudinal right ventricle (RV) strain and strain rate using 2D STE has been reported in dogs. Although longitudinal deformation is the dominant component of the RV systole, RV myocardial fibers of the superficial layer are oriented circumferentially and these contribute to the RV pump function (radial deformation). Because this strain component has not been investigated in dogs, we have assessed radial RV strain and strain rate using 2D STE in healthy dogs and dogs with pulmonary hypertension (PH). We have recruited 74 dogs (40 healthy dogs and 34 dogs with PH) in which we have analyzed radial RV free wall strain and strain rate using XstrainTM software. We have used the left apical 4-chamber view optimized for the RV for analysis of the radial strain and strain rate variables (XstrainTM software denoted radial strain as “transverse”). Seven dogs were excluded during the analysis for low quality images. Transverse strain and strain rate obtained in healthy dogs showed no relationship with heart rate, body weight or age (r2 < 0.09 and p > 0.05 for all variables). Moreover, no relationship between transverse strain/strain rate variables and left atrial-to-aortic ratios was observed (r2 < 0.06 and p = 0.2, for both). Transverse strain and strain rate obtained in dogs with PH, showed weak negative relationships with tricuspid regurgitation velocity (r2 < 0.25 and p = 0.006, for both). Transverse RV strain and strain rate using 2D STE is feasible in most dogs and decrease with worsening of the PH, but these advanced echocardiographic indices do not help in identifying dogs with PH.

scholarly journals High-frequency speckle tracking echocardiography in the assessment of left ventricular function and remodeling after murine myocardial infarction

2014 ◽  
Vol 306 (9) ◽  
pp. H1371-H1383 ◽  
Author(s):  
Amit Bhan ◽  
Alexander Sirker ◽  
Juqian Zhang ◽  
Andrea Protti ◽  
Norman Catibog ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Infarct Size ◽  
Strain Rate ◽  
High Frequency ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Radial Strain ◽  
Left Ventricular ◽  
Intraobserver Variability ◽  
Strain And Strain Rate

The objectives of this study were to assess the feasibility and accuracy of high-frequency speckle tracking echocardiography (STE) in a murine model of myocardial infarction (MI). STE is used clinically to quantify global and regional cardiac function, but its application in mice is challenging because of the small cardiac size and rapid heart rates. A high-frequency microultrasound system with STE (Visualsonics Vevo 2100) was compared against magnetic resonance imaging (MRI) for the assessment of global left ventricular (LV) size and function after murine MI. Animals subjected to coronary ligation ( n = 46) or sham ligation ( n = 27) were studied 4 wk postoperatively. Regional and global deformation were also assessed. STE-derived LV ejection fraction (EF) and mass correlated well with MRI indexes ( r = 0.93, 0.77, respectively; P < 0.001), as did STE-derived mass with postmortem values ( r = 0.80, P < 0.001). Higher STE-derived volumes correlated positively with MRI-derived infarct size ( P < 0.01). Global strain parameters were significantly reduced after MI (all P < 0.001) and strongly correlated with LV mass and MRI-derived infarct size as promising surrogates for the extent of remodeling and infarction, respectively (both P < 0.05). Regional strain analyses showed that radial strain and strain rate were relatively preserved in anterior basal segments after MI compared with more apical segments ( P < 0.001); however, longitudinal strain and strain rate were significantly impaired both basally and distally ( P < 0.001). Strain-derived parameters of dyssynchrony were significantly increased in the MI group ( P < 0.01). Analysis time for STE was 210 ± 45 s with acceptable inter- and intraobserver variability. In conclusion, high-frequency STE enables quantitative assessment of regional and global function in the remodeling murine LV after MI.

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