Effect of longitudinal changes of body fat on the incidence and regression of nonalcoholic fatty liver disease

2018 ◽  
Vol 50 (4) ◽  
pp. 389-395 ◽  
Author(s):  
Donghee Kim ◽  
Goh Eun Chung ◽  
Min-Sun Kwak ◽  
Yoon Jun Kim ◽  
Jung-Hwan Yoon
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Longitudinal Changes

Correlation between body fat mass and nonalcoholic fatty liver disease

2011 ◽  
Vol 6 ◽  
pp. 60-67
Author(s):  
Kuat Oshakbayev ◽  
Alexander Nersesov ◽  
Eldos Izatullayev ◽  
Jamilya Kaybullayeva ◽  
Markhaba Nugmanova ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fat Mass ◽  
Fatty Liver Disease ◽  
Body Fat Mass ◽  
Nonalcoholic Fatty Liver

scholarly journals Waist-to-Hip Ratio is Related to Body Fat Content and Distribution Regardless of the Waist Circumference Measurement Protocol in Nonalcoholic Fatty Liver Disease Patients

2016 ◽  
Vol 26 (4) ◽  
pp. 307-314 ◽  
Author(s):  
Nuno M. Pimenta ◽  
Helena Santa-Clara ◽  
Xavier Melo ◽  
Helena Cortez-Pinto ◽  
José Silva-Nunes ◽  
...  
Keyword(s):  
Liver Disease ◽  
Waist Circumference ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Iliac Crest ◽  
Nonalcoholic Fatty Liver ◽  
Waist To Hip Ratio ◽  
Measurement Protocol

Central accumulation and distribution of body fat (BF) is an important cardiometabolic risk factor. Waist-to-hip ratio (WHR), commonly elevated in nonalcoholic fatty liver disease (NAFLD) patients, has been endorsed as a risk related marker of central BF content and distribution, but no standardized waist circumference measurement protocol (WCmp) has been proposed. We aimed to investigate whether using different WCmp affects the strength of association between WHR and BF content and distribution in NAFLD patients. BF was assessed with dual energy X-ray absorptiometry (DXA) in 28 NAFLD patients (19 males, 51 ± 13 years, and 9 females, 47 ± 13 years). Waist circumference (WC) was measured using four different WCmp (WC1: minimal waist; WC2: iliac crest; WC3: mid-distance between iliac crest and lowest rib; WC4: at the umbilicus) and WHR was calculated accordingly (WHR1, WHR2, WHR3 and WHR4, respectively). High WHR was found in up to 84.6% of subjects, depending on the WHR considered. With the exception of WHR1, all WHR correlated well with abdominal BF (r = .47 for WHR1; r = .59 for WHR2 and WHR3; r = .58 for WHR4) and BF distribution (r = .45 for WHR1; r = .56 for WHR2 and WHR3; r = .51 for WHR4), controlling for age, sex and body mass index (BMI). WHR2 and WHR3 diagnosed exactly the same prevalence of high WHR (76.9%). The present study confirms the strong relation between WHR and central BF, regardless of WCmp used, in NAFLD patients. WHR2 and WHR3 seemed preferable for use in clinical practice, interchangeably, for the diagnosis of high WHR in NAFLD patients.

scholarly journals Associations Between Body Fat, Muscle Mass, and Nonalcoholic Fatty Liver Disease: A Population‐Based Study

2019 ◽  
Vol 3 (8) ◽  
pp. 1061-1072 ◽  
Author(s):  
Julianna C. Hsing ◽  
Mindie H. Nguyen ◽  
Baiyu Yang ◽  
Yan Min ◽  
Summer S. Han ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Muscle Mass ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Population Based ◽  
Population Based Study ◽  
Nonalcoholic Fatty Liver

Hypothyroidism and nonalcoholic fatty liver disease – a chance association?

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Simonetta Lugari ◽  
Alessandro Mantovani ◽  
Fabio Nascimbeni ◽  
Amedeo Lonardo
Keyword(s):  
Liver Disease ◽  
Thyroid Hormone ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Overt Hypothyroidism ◽  
Nonalcoholic Fatty Liver ◽  
Pubmed Database ◽  
Increased Risk

AbstractBackgroundNonalcoholic fatty liver disease (NAFLD) defines the clinical-pathological spectrum of hepatic lipotoxicity, which may progress to hepatic fibrosis and its complications. Thyroid hormone is a master regulator of cell metabolism and body fat distribution. Whether hypothyroidism is associated or not with an increased risk of developing NAFLD and its fibrotic progression is both clinically and physiopathologically relevant. Indeed, answering this research question would carry major pathogenic and therapeutic implications.MethodPubMed database was searched using relevant key-words such as hypothyroidism; NAFLD; nonalcoholic steatohepatitis; cirrhosis; hepatocellular carcinoma; epidemiology; pathogenesis; natural history. The epidemiological studies and the meta-analyses published so far were identified as well as those studies addressing the physiopathology underlying this association.ResultsMany observational studies have investigated the association between either subclinical or overt hypothyroidism and NAFLD. Data are conflicting: some original and meta-analytical studies demonstrated that hypothyroidism, (mainly subclinical hypothyroidism), was common, occurring in approximately 25% of individuals with imaging-defined or biopsy-proven NAFLD; other studies, however, failed to identify a significant association between hypothyroidism and NAFLD. Moreover, such an association is biologically plausible based on the specific physiopathological impact of thyroid hormone and thyroid stimulating hormone (TSH) on metabolism of hepatocytes and accumulation and distribution of body fat.ConclusionsThe findings from the present review support a significant association between primary hypothyroidism and risk of development and progression of NAFLD. However, further studies evaluating the relative importance of subclinical versus overt hypothyroidism as well as addressing the mechanisms underlying the association of hypothyroidism with NAFLD are eagerly awaited.

The Correlation Between Body Fat, Visceral Fat, and Nonalcoholic Fatty Liver Disease

2017 ◽  
Vol 15 (6) ◽  
pp. 304-311 ◽  
Author(s):  
Yun-Huei Ko ◽  
Te-Chih Wong ◽  
Ying-Ying Hsu ◽  
Kuan-Liang Kuo ◽  
Shwu Huey Yang
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Visceral Fat ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver

Body Fat Distribution and Risk of Incident and Regressed Nonalcoholic Fatty Liver Disease

2016 ◽  
Vol 14 (1) ◽  
pp. 132-138.e4 ◽  
Author(s):  
Donghee Kim ◽  
Goh Eun Chung ◽  
Min-Sun Kwak ◽  
Hyo Bin Seo ◽  
Jin Hwa Kang ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Nonalcoholic Fatty Liver
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