The Correlation Between Body Fat, Visceral Fat, and Nonalcoholic Fatty Liver Disease

2017 ◽  
Vol 15 (6) ◽  
pp. 304-311 ◽  
Author(s):  
Yun-Huei Ko ◽  
Te-Chih Wong ◽  
Ying-Ying Hsu ◽  
Kuan-Liang Kuo ◽  
Shwu Huey Yang
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Visceral Fat ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver

Correlation between body fat mass and nonalcoholic fatty liver disease

2011 ◽  
Vol 6 ◽  
pp. 60-67
Author(s):  
Kuat Oshakbayev ◽  
Alexander Nersesov ◽  
Eldos Izatullayev ◽  
Jamilya Kaybullayeva ◽  
Markhaba Nugmanova ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fat Mass ◽  
Fatty Liver Disease ◽  
Body Fat Mass ◽  
Nonalcoholic Fatty Liver

scholarly journals Waist-to-Hip Ratio is Related to Body Fat Content and Distribution Regardless of the Waist Circumference Measurement Protocol in Nonalcoholic Fatty Liver Disease Patients

2016 ◽  
Vol 26 (4) ◽  
pp. 307-314 ◽  
Author(s):  
Nuno M. Pimenta ◽  
Helena Santa-Clara ◽  
Xavier Melo ◽  
Helena Cortez-Pinto ◽  
José Silva-Nunes ◽  
...  
Keyword(s):  
Liver Disease ◽  
Waist Circumference ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Iliac Crest ◽  
Nonalcoholic Fatty Liver ◽  
Waist To Hip Ratio ◽  
Measurement Protocol

Central accumulation and distribution of body fat (BF) is an important cardiometabolic risk factor. Waist-to-hip ratio (WHR), commonly elevated in nonalcoholic fatty liver disease (NAFLD) patients, has been endorsed as a risk related marker of central BF content and distribution, but no standardized waist circumference measurement protocol (WCmp) has been proposed. We aimed to investigate whether using different WCmp affects the strength of association between WHR and BF content and distribution in NAFLD patients. BF was assessed with dual energy X-ray absorptiometry (DXA) in 28 NAFLD patients (19 males, 51 ± 13 years, and 9 females, 47 ± 13 years). Waist circumference (WC) was measured using four different WCmp (WC1: minimal waist; WC2: iliac crest; WC3: mid-distance between iliac crest and lowest rib; WC4: at the umbilicus) and WHR was calculated accordingly (WHR1, WHR2, WHR3 and WHR4, respectively). High WHR was found in up to 84.6% of subjects, depending on the WHR considered. With the exception of WHR1, all WHR correlated well with abdominal BF (r = .47 for WHR1; r = .59 for WHR2 and WHR3; r = .58 for WHR4) and BF distribution (r = .45 for WHR1; r = .56 for WHR2 and WHR3; r = .51 for WHR4), controlling for age, sex and body mass index (BMI). WHR2 and WHR3 diagnosed exactly the same prevalence of high WHR (76.9%). The present study confirms the strong relation between WHR and central BF, regardless of WCmp used, in NAFLD patients. WHR2 and WHR3 seemed preferable for use in clinical practice, interchangeably, for the diagnosis of high WHR in NAFLD patients.

scholarly journals Clinical Predictors of Liver Fibrosis Presence and Progression in Human Immunodeficiency Virus–Associated Nonalcoholic Fatty Liver Disease

2020 ◽  
Author(s):  
Lindsay T Fourman ◽  
Takara L Stanley ◽  
Isabel Zheng ◽  
Chelsea S Pan ◽  
Meghan N Feldpausch ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Hepatic Fibrosis ◽  
Visceral Fat ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Fibrosis Progression ◽  
Immunodeficiency Virus

Abstract Background Nonalcoholic fatty liver disease (NAFLD) affects more than one-third of people living with human immunodeficiency virus (HIV). Nonetheless, its natural history is poorly understood, including which patients are most likely to have a progressive disease course. Methods We leveraged a randomized trial of the growth hormone–releasing hormone analogue tesamorelin to treat NAFLD in HIV. Sixty-one participants with HIV-associated NAFLD were randomized to tesamorelin or placebo for 12 months with serial biopsies. Results In all participants with baseline biopsies (n = 58), 43% had hepatic fibrosis. Individuals with fibrosis had higher NAFLD Activity Score (NAS) (mean ± standard deviation [SD], 3.6 ± 2.0 vs 2.0 ± 0.8; P < .0001) and visceral fat content (mean ± SD, 284 ± 91 cm2 vs 212 ± 95 cm2; P = .005), but no difference in hepatic fat or body mass index. Among placebo-treated participants with paired biopsies (n = 24), 38% had hepatic fibrosis progression over 12 months. For each 25 cm2 higher visceral fat at baseline, odds of fibrosis progression increased by 37% (odds ratio, 1.37 [95% confidence interval, 1.03–2.07]). There was no difference in baseline NAS between fibrosis progressors and nonprogressors, though NAS rose over time in the progressor group (mean ± SD, 1.1 ± 0.8 vs −0.5 ± 0.6; P < .0001). Conclusions In this longitudinal study of HIV-associated NAFLD, high rates of hepatic fibrosis and progression were observed. Visceral adiposity was identified as a novel predictor of worsening fibrosis. In contrast, baseline histologic characteristics did not relate to fibrosis progression.

scholarly journals Associations Between Body Fat, Muscle Mass, and Nonalcoholic Fatty Liver Disease: A Population‐Based Study

2019 ◽  
Vol 3 (8) ◽  
pp. 1061-1072 ◽  
Author(s):  
Julianna C. Hsing ◽  
Mindie H. Nguyen ◽  
Baiyu Yang ◽  
Yan Min ◽  
Summer S. Han ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Muscle Mass ◽  
Body Fat ◽  
Fatty Liver Disease ◽  
Population Based ◽  
Population Based Study ◽  
Nonalcoholic Fatty Liver
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