Inducing sex reversal of the urogenital system of marsupials

2014 ◽  
Vol 87 (1-2) ◽  
pp. 23-31 ◽  
Author(s):  
Marilyn B. Renfree ◽  
Keng Yih Chew ◽  
Geoff Shaw
Keyword(s):  
Sex Reversal ◽  
Urogenital System

The Region on 9p Associated with 46,XY Sex Reversal Contains Several Transcripts Expressed in the Urogenital System and a Novel Doublesex-Related Domain

Genomics ◽  
2000 ◽  
Vol 64 (2) ◽  
pp. 170-178 ◽  
Author(s):  
Chris Ottolenghi ◽  
Reiner Veitia ◽  
Lluis Quintana-Murci ◽  
Delphine Torchard ◽  
Luca Scapoli ◽  
...  
Keyword(s):  
Sex Reversal ◽  
Urogenital System ◽  
Xy Sex Reversal

Iron Metabolism in the Human Body and Setting its Hygienic Limits for Drinking Water. Review. Part 2

2020 ◽  
Vol 99 (5) ◽  
pp. 504-508
Author(s):  
Natalija A. Egorova ◽  
N. V. Kanatnikova
Keyword(s):  
Oxidative Stress ◽  
Drinking Water ◽  
Iron Overload ◽  
Iron Metabolism ◽  
Subcutaneous Tissue ◽  
Allergic Diseases ◽  
The Body ◽  
Urogenital System ◽  
High Iron Content ◽  
Labile Iron Pool

Iron is an assential element for the growth, division, differentiation and functioning of any cell in the body. Iron is virtually important for human and danger at the same time, because with excessive accumulation it causes oxidative stress with formation of highly active oxygen radicals and reactive form of nitrogen that can destroy cell membranes, proteins, nucleic acids, reduce cell viability, with, according to modern concepts, can contribute to the development of many diseases (cardiovascular, rheumatic, gastrointestinal, neurodegenerative, oncological, metabolic and others), and also accelerate the aging process. Part 1 of this review discussed the issues of iron metabolism in human, including its regulation at the cellular and systemic levels, the intake, transport, use, accumulation and export of iron in cells, the role of the labile iron pool in the cytoplasm of cells and plasma non-transferrin bound iron. Data are provided on the causes, frequency and significance of iron overload in the formation of free radicals and the development of oxidative stress. Part 2 of the review provides information on diseases associated with iron overload as well as information on ferroptosis - a new type of iron-dependent regulated cell death. Attention is paid to the works of domestic authors, where it was found that prolonged use of drinking water with a high iron content is unfavorable for the population and leads to an increase in the overall incidence, the development of the diseases of the blood, skin and subcutaneous tissue, musculoskeletal system, digestive system, urogenital system, and allergic diseases. Separate publications are cited on the possibility of a negative effect of iron at concentrations in water of 0.3 mg/l and lower. The material of the review emphasizes the preventive significance of caution attitude to regulating iron in the water in the Russian Federation, where 1/3 of the population uses iron-containing water for drinking, and substantiate the feasibility of establishing a hygienic limit for iron in water not higher than 0.3 mg/l.

scholarly journals Association of neural tube defects with congenital abnormalities of the urogenital system in a Chinese cohort

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhi-Hua Hong ◽  
Dong-Hui Jin ◽  
Xiao-Jian Yuan ◽  
Yang Zhao ◽  
Hou-Wei Lin ◽  
...  
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Congenital Abnormality ◽  
Congenital Abnormalities ◽  
Urogenital System ◽  
Urinary System ◽  
Intravenous Pyelography ◽  
Abdominal Organs ◽  
Chinese Cohort ◽  
Urogenital Malformation

Abstract Background This study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs). Methods A total of 190 children with congenital NTDs, who were admitted to a hospital from May 2013 to May 2018, were included into the present study. All admitted children with congenital NTDs were carried out routine abdominal B-ultrasound examinations to determine the malformations of the abdominal organs, including the urinary system. Children with a B-ultrasound result of suspected and unsure malformation underwent intravenous pyelography (IVP) and voiding cysto-urethrography (VCU), and this was further confirmed by the CT results. Results The incidence of urogenital malformation was 12.1% (23/190) in children with congenital NTDs. For the 23 children with urogenital malformations, most of these children had no definite urinary system symptoms, while some of these children had multiple incidences of urinary system infections. Conclusions Congenital NTDs are often combined with urogenital malformations, if not specifically searched these may be overlooked. The early detection of these malformations is beneficial to reduce the risk of operation and improve the prognosis.

Effects of Different Stocking Densities on Growth, Serum Steroid Hormone Concentrations, Gonadosomatic Index and Sex Reversal in the Rice Field Eel, Monopterus albus (Zuiew)

2011 ◽  
Vol 142 ◽  
pp. 233-237
Author(s):  
Han Wen Yuan ◽  
Fang Chen ◽  
Qiao Qing Xu ◽  
Shi Yuan Gong ◽  
Zhang Jie Chu ◽  
...  
Keyword(s):  
Rice Field ◽  
Steroid Hormone ◽  
Gonadosomatic Index ◽  
Stocking Density ◽  
Sex Reversal ◽  
The Other ◽  
Daily Weight Gain ◽  
Monopterus Albus ◽  
Rice Field Eel ◽  
Significant Difference

The effects of stocking density on various growth parameters and sex reversal in the rice field eel (Monopterus albus) were investigated by evaluating steroid hormone, the gonadosomatic index (GSI) and sex ratio. Fish (mean initial weight of 9.88 ± 0.70 g) were stocked to densities of 4, 20, 36, 52, 68, 84 or 100 fish/m2 in cages (2 m × 1 m × 1.5 m) in a pond, with five replicate cages for each density. Fish were fed for 420 days on a formulated isocaloric diet containing 40.22% crude protein and 12.86 MJ/kg. Serum E2 and T concentrations were determined by radioimmunoassays. There were no significant differences in final bodyweight (FBW) and daily weight gain (DWG) for fish in the groups containing less than 52 fish/m2, while FBW and DWG were significant lower in groups at 68 fish/m2 or more. Specific growth rate (SGR) differed significantly between the 84 and 100 fish/m2 groups compared with the 4, 20 and 36 fish/m2 groups. There was no significant difference in SGR in groups containing less than 84 fish/m2. There were no significant difference between the 4 and 20 fish/m2 groups in net yield (NY), but these groups did differ significantly from the other groups. The final condition factors of fish stocked at 84 or 100 fish/m2 were significantly lower than fish stocked at the other densities. E2 and T hormone concentrations declined as stocking density increased, while GSI values increased initially but then reduced with increasing stocking density. Female ratio and survival decreased with increasing stocking density. The proportion of male fish was significantly greater in the three highest stocking density groups. Therefore, high stocking density may promote sex change from female to male in M. albus.

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