scholarly journals Linearity analysis and comparison study on the epoc® point-of-care blood analysis system in cardiopulmonary bypass patients

Data in Brief ◽  
2016 ◽  
Vol 6 ◽  
pp. 847-852 ◽  
Author(s):  
Jianing Chen ◽  
Monique Gorman ◽  
Bill O’Reilly ◽  
Yu Chen
2015 ◽  
Vol 48 (15) ◽  
pp. 1013
Author(s):  
Yu Chen ◽  
Monique Gorman ◽  
Bill O'Reilly

Perfusion ◽  
1997 ◽  
Vol 12 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Kelly D Hedlund ◽  
Scott Oen ◽  
Leo LaFauce ◽  
D Michael Sanford

The Immediate Response Mobile Analysis (IRMA) blood analysis system (Diametrics Medical Incorporated, St Paul, MN, USA) is a new point-of-care testing device that uses technology similar to the Gem Premier (Mallinckrodt Sensor Systems Incorporated, Ann Arbor, MI, USA), which are ion-specific electrodes. We compared these two analysers using both patient blood samples ( n = 50) and aqueous quality control solutions ( n = 45). Linear regression (Pearson product-moment correlation coefficient) was performed to quantify the strength of the association between results. In addition, bias and precision were determined in accordance with the method described by Bland and Altman.1 The results demonstrated excellent correlation between the IRMA and the Gem Premier, and bias and precision were acceptable for both patient and quality control samples. Reproducibility of results was also assessed using one level of aqueous quality control solution ( n = 50). The IRMA demonstrated very little variance in parameter readings over a five-day study period.


2018 ◽  
Author(s):  
Chiao-Hsun Yang ◽  
Yu-Ling Hsieh ◽  
Ping-Hsien Tsou ◽  
Bor-Ran Li

AbstractBlood tests provide crucial diagnostic information regarding several diseases. A key factor that affects the precision and accuracy of blood tests is the interference of red blood cells; however, the conventional methods of blood separation are often complicated and time consuming. In this study, we devised a simple but high-efficiency blood separation system on a self-strained microfluidic device that separates 99.7% of the plasma in only 6 min. Parameters, such as flow rate, design of the filter trench, and the relative positions of the filter trench and channel, were optimized through microscopic monitoring. Moreover, this air-difference-driven device uses a cost-effective and easy-to-use heater strip that creates a low-pressure environment in the microchannel within minutes. With the aforementioned advantages, this blood separation device could be another platform choice for point-of-care testing.


1994 ◽  
Vol 40 (1) ◽  
pp. 124-129 ◽  
Author(s):  
R J Wong ◽  
J J Mahoney ◽  
J A Harvey ◽  
A L Van Kessel

Abstract We evaluated a new portable instrument, the PPG StatPal II pH and Blood Gas Analysis System, designed for "point-of-care" measurements of blood gases and pH. Inaccuracy (% of target value) and imprecision (CV%) were assessed by blood tonometry and comparison with a Corning 178. Within-day results for PCO2 inaccuracy and imprecision ranged from 98.2% to 102.9% and 3.3% to 3.9%, respectively; for PO2, these were 95.5% to 102.3% and 2.3% to 3.0%, respectively. Between-day results for PCO2 inaccuracy and imprecision ranged from 99.2% to 99.3% and from 2.9% to 3.2%, respectively; for PO2, the ranges were 96.2% to 98.2% and 2.6% to 3.0%, respectively. Two PCO2 outliers (in 645 samples = 0.3%) were observed. In general, tonometry recovery, measurement stability, and pH bias results for the StatPal II and Corning 178 were comparable. We conclude that the StatPal II performs within acceptable ranges of inaccuracy and imprecision.


Author(s):  
Hadar Ben-Yoav ◽  
Sheryl E. Chocron ◽  
Thomas E. Winkler ◽  
Eunkyoung Kim ◽  
Gregory F. Payne ◽  
...  

Perfusion ◽  
2019 ◽  
Vol 35 (2) ◽  
pp. 138-144
Author(s):  
Helena Argiriadou ◽  
Polychronis Antonitsis ◽  
Anna Gkiouliava ◽  
Evangelia Papapostolou ◽  
Apostolos Deliopoulos ◽  
...  

Introduction: Cardiac surgery on conventional cardiopulmonary bypass induces a combination of thrombocytopenia and platelet dysfunction which is strongly related to postoperative bleeding. Minimal invasive extracorporeal circulation has been shown to preserve coagulation integrity, though effect on platelet function remains unclear. We aimed to prospectively investigate perioperative platelet function in a series of patients undergoing cardiac surgery on minimal invasive extracorporeal circulation using point-of-care testing. Methods: A total of 57 patients undergoing elective cardiac surgery on minimal invasive extracorporeal circulation were prospectively recruited. Anticoagulation strategy was based on individualized heparin management and heparin level–guided protamine titration performed in all patients with a specialized point-of-care device (Hemostasis Management System – HMS Plus; Medtronic, Minneapolis, MN, USA). Platelet function was evaluated with impedance aggregometry using the ROTEM platelet (TEM International GmbH, Munich, Germany). ADPtest and TRAPtest values were assessed before surgery and after cardiopulmonary bypass. Results: ADPtest value was preserved during surgery on minimal invasive extracorporeal circulation (58.2 ± 20 U vs. 53.6 ± 21 U; p = 0.1), while TRAPtest was found significantly increased (90 ± 27 U vs. 103 ± 38 U; p = 0.03). Postoperative ADPtest and TRAPtest values were inversely related to postoperative bleeding (correlation coefficient: −0.29; p = 0.03 for ADPtest and correlation coefficient: −0.28; p = 0.04 for TRAPtest). The preoperative use of P2Y12 inhibitors was identified as the only independent predictor of a low postoperative ADPtest value (OR = 15.3; p = 0.02). Conclusion: Cardiac surgery on minimal invasive extracorporeal circulation is a platelet preservation strategy, which contributes to the beneficial effect of minimal invasive extracorporeal circulation in coagulation integrity.


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