scholarly journals The Sweet and Sour Taste of Phosphoinositide Signaling: Protonation of PI4P Modulates Its Function in Response to Cytoplasmic pH Changes

2020 ◽  
Vol 52 (4) ◽  
pp. 395-397 ◽  
Author(s):  
Oliver Schmidt ◽  
Maria Bohnert
Keyword(s):  
Cytoplasmic Ph ◽  
Sour Taste ◽  
Phosphoinositide Signaling ◽  
Ph Changes

Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes

1993 ◽  
Vol 53 (6) ◽  
pp. 673-678 ◽  
Author(s):  
John Bernardo ◽  
Lisa Brennan ◽  
Holly F. Brink ◽  
Maria F. Ortiz ◽  
Peter E. Newburger ◽  
...  
Keyword(s):  
Human Monocytes ◽  
Cytoplasmic Ph ◽  
Chemotactic Peptide ◽  
Ph Changes

NMR study of low subcellular pH during the development of cherry tomato fruit

2000 ◽  
Vol 27 (1) ◽  
pp. 61 ◽  
Author(s):  
Dominique Rolin ◽  
Pierre Baldet ◽  
Daniel Just ◽  
Christian Chevalier ◽  
Marc Biran ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Organic Acids ◽  
Fruit Development ◽  
Tomato Fruit ◽  
31P Nmr Spectroscopy ◽  
Cytoplasmic Ph ◽  
Cherry Tomato ◽  
Ph Changes ◽  
Nmr Study

Changes in metabolites (organic acids, sugars and amino acids) and subcellular pH were studied during fruit development of cherry tomato (Lycopersicon esculentum Mill. var. cerasiformae). Fructose and glucose were the major sugars, whereas citrate and malate the two major organic acids. At different stages of fruit development, vacuolar and cytoplasmic pH changes were followed by in vivo 13C and 31P NMR spectroscopy. Fruit compartments had a cytoplasmic pH around 7.1 as early as the cell-divi-sion and -expansion stages. The vacuolar pH measured by in vivo 13C NMR spectroscopy decreased from 4.5 to 3.6. Concomitantly, strong accumulation of γ-aminobutyric acid (GABA) was observed during the first 15 days after anthesis and glutamate decarboxylase (GAD) activity increased 10-fold during the first 8 days of development. The relationships between organic acid biosynthesis and storage, GABA produc-tion, and subcellular pH changes during development of cherry tomato fruit are discussed.

31P NMR Measurements of Cytoplasmic pH Changes in Maize Root Tips

1985 ◽  
Vol 36 (6) ◽  
pp. 889-897 ◽  
Author(s):  
R. J. REID ◽  
B. C. LOUGHMAN ◽  
R. G. RATCLIFFE
Keyword(s):  
31P Nmr ◽  
Maize Root ◽  
Cytoplasmic Ph ◽  
Root Tips ◽  
Ph Changes

Transient Cytoplasmic pH Changes in Correlation with Opening of Potassium Channels inEremosphaera

1988 ◽  
Vol 39 (1) ◽  
pp. 23-36 ◽  
Author(s):  
W. STEIGNER ◽  
K. KÖHLER ◽  
W. SIMONIS ◽  
W. URBACH
Keyword(s):  
Potassium Channels ◽  
Cytoplasmic Ph ◽  
Ph Changes

A Mechanism for Reversibly Pausing a Self-Immolation Cascade in Response to pH Changes

2019 ◽  
Author(s):  
Derrick Roberts ◽  
Ben S. Pilgrim ◽  
Tristan Dell ◽  
Molly Stevens
Keyword(s):  
Local Environment ◽  
Chemical Signals ◽  
Ph Sensitive ◽  
First Report ◽  
Ph Changes ◽  
Self Immolation

We describe the first report of a self-immolation cascade that can be reversibly paused and reactivated in response to pH changes. This system employs a triazole-based self-immolative linker, which expresses a pH-sensitive intermediate during its elimination sequence. This allows the system to respond to pH cues within its local environment, thus establishing a new way to gate self-immolative release using fluctuating or transient chemical signals.<br>

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