scholarly journals Wolbachia Control Stem Cell Behavior and Stimulate Germline Proliferation in Filarial Nematodes

2018 ◽  
Vol 45 (2) ◽  
pp. 198-211.e3 ◽  
Author(s):  
Vincent Foray ◽  
Mercedes M. Pérez-Jiménez ◽  
Nour Fattouh ◽  
Frédéric Landmann
Keyword(s):  
Stem Cell ◽  
Cell Behavior ◽  
Filarial Nematodes ◽  
Germline Proliferation

scholarly journals Wolbachia control stem cell behavior and stimulate germline proliferation in filarial nematodes

2018 ◽  
Author(s):  
Foray Vincent ◽  
Pérez-Jiménez Mercedes M. ◽  
Fattouh Nour ◽  
Landmann Frédéric
Keyword(s):  
Stem Cell ◽  
Germline Stem Cell ◽  
Cell Behavior ◽  
Germline Stem Cells ◽  
Developmental Program ◽  
Symbiotic Interactions ◽  
Filarial Nematodes ◽  
A Cell ◽  
Germline Proliferation

SUMMARYAlthough symbiotic interactions are ubiquitous in the living world, examples of developmental symbioses are still scarce. We show here the crucial role of Wolbachia in the oogenesis of filarial nematodes, a class of parasites of biomedical and veterinary relevance. While the Wolbachia-depleted nematodes produce faulty embryos, we identified thanks to newly generated techniques the earliest requirements of Wolbachia in the germline. They stimulate its proliferation in a cell-autonomous manner, in parallel of the known key controllers, and not through nucleotide supplementation as previously hypothesized. We also found Wolbachia to maintain the quiescence of a pool of germline stem cells ensuring for many years a constant delivery of about 1400 eggs per day. The loss of quiescence upon Wolbachia depletion, as well as the disorganization of the distal germline suggest that Wolbachia are required to execute the proper germline stem cell developmental program in order to produce viable eggs and embryos.

Mechanical loading and the control of stem cell behavior

2021 ◽  
Vol 125 ◽  
pp. 105092
Author(s):  
Jeeranan Manokawinchoke ◽  
Prasit Pavasant ◽  
Chalida Nakalekha Limjeerajarus ◽  
Nuttapol Limjeerajarus ◽  
Thanaphum Osathanon ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mechanical Loading ◽  
Cell Behavior

Three-Dimensional Melt-Electrowritten Polycaprolactone/Chitosan Scaffolds Enhance Mesenchymal Stem Cell Behavior

2021 ◽  
Vol 4 (2) ◽  
pp. 1319-1329
Author(s):  
Minami Yoshida ◽  
Paul R. Turner ◽  
M. Azam Ali ◽  
Jaydee D. Cabral
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Three Dimensional ◽  
Cell Behavior ◽  
Chitosan Scaffolds

Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels

Soft Matter ◽  
2012 ◽  
Vol 8 (31) ◽  
pp. 8113 ◽  
Author(s):  
Ross A. Marklein ◽  
Danielle E. Soranno ◽  
Jason A. Burdick
Keyword(s):  
Stem Cell ◽  
Adult Stem Cell ◽  
Cell Behavior ◽  
3 Dimensional ◽  
Mechanical Signals

Chemical interaction of polyphosphoric acid with titanium and its effect on human bone marrow derived mesenchymal stem cell behavior

2007 ◽  
Vol 82A (1) ◽  
pp. 195-200 ◽  
Author(s):  
Kenji Maekawa ◽  
Yasuhiro Yoshida ◽  
Atsushi Mine ◽  
Takuo Fujisawa ◽  
Bart Van Meerbeek ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Polyphosphoric Acid ◽  
Chemical Interaction ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Cell Behavior

scholarly journals Mobilizing Endogenous Repair Through Understanding Immune Reaction With Biomaterials

2021 ◽  
Vol 9 ◽  
Author(s):  
Maria Karkanitsa ◽  
Parinaz Fathi ◽  
Tran Ngo ◽  
Kaitlyn Sadtler
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Immune System ◽  
Regenerative Medicine ◽  
Tissue Repair ◽  
Immune Reaction ◽  
Cell Behavior ◽  
Physical Trauma ◽  
Injured Tissue ◽  
Natural Healing

With few exceptions, humans are incapable of fully recovering from severe physical trauma. Due to these limitations, the field of regenerative medicine seeks to find clinically viable ways to repair permanently damaged tissue. There are two main approaches to regenerative medicine: promoting endogenous repair of the wound, or transplanting a material to replace the injured tissue. In recent years, these two methods have fused with the development of biomaterials that act as a scaffold and mobilize the body’s natural healing capabilities. This process involves not only promoting stem cell behavior, but by also inducing activity of the immune system. Through understanding the immune interactions with biomaterials, we can understand how the immune system participates in regeneration and wound healing. In this review, we will focus on biomaterials that promote endogenous tissue repair, with discussion on their interactions with the immune system.

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