Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels

Soft Matter ◽  
2012 ◽  
Vol 8 (31) ◽  
pp. 8113 ◽  
Author(s):  
Ross A. Marklein ◽  
Danielle E. Soranno ◽  
Jason A. Burdick
Keyword(s):  
Stem Cell ◽  
Adult Stem Cell ◽  
Cell Behavior ◽  
3 Dimensional ◽  
Mechanical Signals

scholarly journals Regulation of adult stem cell behavior by nutrient signaling

Cell Cycle ◽  
2011 ◽  
Vol 10 (16) ◽  
pp. 2628-2634 ◽  
Author(s):  
Lei Wang ◽  
Catherine McLeod ◽  
D. Leanne Jones
Keyword(s):  
Stem Cell ◽  
Adult Stem Cell ◽  
Cell Behavior ◽  
Nutrient Signaling

scholarly journals Lipid Mediated Regulation of Adult Stem Cell Behavior

2020 ◽  
Vol 8 ◽  
Author(s):  
Marie Clémot ◽  
Rafael Sênos Demarco ◽  
D. Leanne Jones
Keyword(s):  
Stem Cell ◽  
Adult Stem Cell ◽  
Cell Behavior

Control of adult stem cell behavior with biomaterials

2014 ◽  
Vol 11 (6) ◽  
pp. 423-430 ◽  
Author(s):  
Soojin Kim ◽  
Byung-Soo Kim
Keyword(s):  
Stem Cell ◽  
Adult Stem Cell ◽  
Cell Behavior

scholarly journals Physicochemical Control of Adult Stem Cell Differentiation: Shedding Light on Potential Molecular Mechanisms

2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Igor Titushkin ◽  
Shan Sun ◽  
Jennifer Shin ◽  
Michael Cho
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Molecular Mechanisms ◽  
Adult Stem Cell ◽  
Stem Cell Differentiation ◽  
Cell Behavior ◽  
Soluble Factors ◽  
Multiple Differentiation ◽  
Exciting Potential ◽  
Physical Forces

Realization of the exciting potential for stem-cell-based biomedical and therapeutic applications, including tissue engineering, requires an understanding of the cell-cell and cell-environment interactions. To this end, recent efforts have been focused on the manipulation of adult stem cell differentiation using inductive soluble factors, designing suitable mechanical environments, and applying noninvasive physical forces. Although each of these different approaches has been successfully applied to regulate stem cell differentiation, it would be of great interest and importance to integrate and optimally combine a few or all of the physicochemical differentiation cues to induce synergistic stem cell differentiation. Furthermore, elucidation of molecular mechanisms that mediate the effects of multiple differentiation cues will enable the researcher to better manipulate stem cell behavior and response.

scholarly journals Controlling Adult Stem Cell Behavior Using Nanodiamond-Reinforced Hydrogel: Implication in Bone Regeneration Therapy

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Settimio Pacelli ◽  
Ryan Maloney ◽  
Aparna R. Chakravarti ◽  
Jonathan Whitlow ◽  
Sayantani Basu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Bone Regeneration ◽  
Adult Stem Cell ◽  
Cell Behavior
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