scholarly journals Systematic review and meta-analysis of radiotherapy in various head and neck cancers: Comparing photons, carbon-ions and protons

2011 ◽  
Vol 37 (3) ◽  
pp. 185-201 ◽  
Author(s):  
Bram L.T. Ramaekers ◽  
Madelon Pijls-Johannesma ◽  
Manuela A. Joore ◽  
Piet van den Ende ◽  
Johannes A. Langendijk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Meta Analysis ◽  
Head And Neck Cancers ◽  
Carbon Ions

SBRT for Primary Head and Neck Cancers: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 108 (3) ◽  
pp. e834
Author(s):  
N. Malik ◽  
M. Kim ◽  
H. Chen ◽  
I. Poon ◽  
Z.A. Husain ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Meta Analysis ◽  
Head And Neck Cancers

scholarly journals Hyperthermia and radiotherapy in the management of head and neck cancers: A systematic review and meta-analysis

2015 ◽  
Vol 32 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Niloy R. Datta ◽  
Susanne Rogers ◽  
Silvia Gómez Ordóñez ◽  
Emsad Puric ◽  
Stephan Bodis
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Meta Analysis ◽  
Head And Neck Cancers

scholarly journals Prognostic Utility of Platelet–Lymphocyte Ratio, Neutrophil–Lymphocyte Ratio and Monocyte–Lymphocyte Ratio in Head and Neck Cancers: A Detailed PRISMA Compliant Systematic Review and Meta-Analysis

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4166
Author(s):  
Chellan Kumarasamy ◽  
Vaibhav Tiwary ◽  
Krishnan Sunil ◽  
Deepa Suresh ◽  
Sameep Shetty ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Large Scale ◽  
Prognostic Markers ◽  
Meta Analysis ◽  
Head And Neck Cancers ◽  
Bibliographic Databases ◽  
Neutrophil Lymphocyte Ratio ◽  
Clinical Method ◽  
Lymphocyte Ratio

Inflammation plays a major role in cancer development and progression and has the potential to be used as a prognostic marker in cancer. Previous studies have attempted to evaluate Platelet-to-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) as indicators of inflammation/prognostic markers in cancer, but there is no common consensus on their application in clinical practice. The aim of this systematic review and meta-analysis is to (a) assess the prognostic efficacy of all three prognostic markers in comparison to each other and (b) investigate the prognostic potential of these three markers in HNC. The study followed PRISMA guidelines, with the literature being collated from multiple bibliographic databases. Preliminary and secondary screening were carried out using stringent inclusion/exclusion criteria. Meta-analysis was carried out on selected studies using CMA software and HR as the pooled effect size metric. A total of 49 studies were included in the study. The pooled HR values of PLR, NLR and MLR indicated that they were significantly correlated with poorer OS. The pooled effect estimates for PLR, NLR and MLR were 1.461 (95% CI 1.329–1.674), 1.639 (95% CI 1.429–1.880) and 1.002 (95% CI 0.720–1.396), respectively. Significant between-study heterogeneity was observed in the meta-analysis of all three. The results of this study suggest that PLR, NLR and MLR ratios can be powerful prognostic markers in head and neck cancers that can guide treatment. Further evidence from large-scale clinical studies on patient cohorts are required before they can be incorporated as a part of the clinical method. PROSPERO Registration ID: CRD42019121008

scholarly journals 76Past dental visits and incidence of head and neck cancers: a systematic review and meta-analysis

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Bhawna Gupta
Keyword(s):  
Systematic Review ◽  
Oral Cavity ◽  
Head And Neck ◽  
Meta Analysis ◽  
Population Based ◽  
Head And Neck Cancers ◽  
Public Health Burden ◽  
Dental Visits ◽  
Oral Cancers ◽  
Incident Cases

Abstract Background The aim of this study was to conduct a quantitative assessment of any independent association between past dental visits/check-ups and incidence of cancers of HN/upper aero-digestive tract (UADT) and oral cavity worldwide. Methods PubMed, CINAHL, and Cochrane databases were searched for all observational studies published until August 2017 that assessed an association of past dental visits/dental check-ups among the incident cases of HNC/UADT cancers. Three different meta-analyses were conducted: two based on the incident cancer reported in the studies (HNCs/cancers of UADT and oral cavity); another included all studies irrespective of the type of cancer reported with the frequency of past dental visits as subgroups. Results Sixty-two articles were reviewed in full, but only 38 were eligible for inclusion. Under the random effects model, odds of past never/irregular/ not frequent dental visits were greater in HNC cases and oral cancer cases as compared to the hospital based/ population-based controls [HNCs-unadjusted odds ratio (OR) 2.24; 95% confidence interval (CI) 1.89 to 2.65) and (oral cancers—OR 1.93; 95% CI 1.47 to 2.52]. There was no publication bias in our study. Conclusion This systematic review and meta-analysis indicates that individuals with never/irregular/not frequent dental visits are more likely to be incident cases of HNCs/UADT cancers. Key message Regular/frequent dental visits, at least annually, can aid in reducing the public health burden of head and neck cancers (HNCs) by facilitating earlier detection of the disease.

HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis

2014 ◽  
Vol 15 (12) ◽  
pp. 1319-1331 ◽  
Author(s):  
Cathy Ndiaye ◽  
Marisa Mena ◽  
Laia Alemany ◽  
Marc Arbyn ◽  
Xavier Castellsagué ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Meta Analysis ◽  
Head And Neck Cancers ◽  
Hpv Dna
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