scholarly journals Anatomical predictors of successful prism adaptation in chronic visual neglect

Cortex ◽  
2019 ◽  
Vol 120 ◽  
pp. 629-641 ◽  
Author(s):  
Marine Lunven ◽  
Gilles Rode ◽  
Clémence Bourlon ◽  
Christophe Duret ◽  
Raffaella Migliaccio ◽  
...  
Keyword(s):  
Prism Adaptation ◽  
Visual Neglect

scholarly journals Anatomical predictors of recovery from visual neglect after prism adaptation therapy

2015 ◽  
Vol 58 ◽  
pp. e29 ◽  
Author(s):  
M. Lunven ◽  
M. Thiebaut De Schotten ◽  
C. Bourlon ◽  
R. Migliaccio ◽  
K. Moreau ◽  
...  
Keyword(s):  
Prism Adaptation ◽  
Visual Neglect

Long-term effects of prism adaptation in chronic visual neglect: A single case study

2006 ◽  
Vol 23 (3) ◽  
pp. 463-478 ◽  
Author(s):  
Glyn W. Humphreys ◽  
Alexia Watelet ◽  
M. Jane Riddoch
Keyword(s):  
Single Case ◽  
Prism Adaptation ◽  
Single Case Study ◽  
Long Term Effects ◽  
Visual Neglect

Implications of prism adaptation asymmetry for unilateral visual neglect: Theoretical note

Cortex ◽  
2010 ◽  
Vol 46 (3) ◽  
pp. 390-396 ◽  
Author(s):  
Gordon M. Redding ◽  
Benjamin Wallace
Keyword(s):  
Prism Adaptation ◽  
Visual Neglect

scholarly journals Anatomical predictors of successful prism adaptation in chronic visual neglect

2017 ◽  
Author(s):  
Marine Lunven ◽  
Gilles Rode ◽  
Clémence Bourlon ◽  
Christophe Duret ◽  
Raffaella Migliaccio ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
The Body ◽  
Prism Adaptation ◽  
Visual Neglect ◽  
Non Invasive ◽  
Right Hemisphere Damage ◽  
Probable Role ◽  
Convenient Technique ◽  
The Relationship

AbstractVisual neglect is a frequent and disabling consequence of right hemisphere damage. Previous work demonstrated a probable role of posterior callosal dysfunction in the chronic persistence of neglect signs. Prism adaptation is a non-invasive and convenient technique to rehabilitate chronic visual neglect, but it is not effective in all patients. Here we aimed to assess the hypothesis that prism adaptation improves left neglect by facilitating compensation through the contribution of the left, undamaged hemisphere. We assessed the relationship between prism adaptation effects, cortical thickness and white matter integrity in a group of 14 patients with unilateral right-hemisphere strokes and chronic visual neglect. Results showed that patients who benefitted from prism adaptation had thicker cortex in temporo-parietal, prefrontal and cingulate areas of the left, undamaged hemisphere. Additionally, these patients had a higher fractional anisotropy value in the body and genu of the corpus callosum. Results from normal controls show that these callosal regions connect temporo-parietal, sensorimotor and prefrontal areas. Finally, shorter time intervals from the stroke tended to improve patients’ response to prism adaptation. We concluded that prism adaptation may improve left visual neglect by promoting the contribution of the left hemisphere to neglect compensation. These results support current hypotheses on the role of the healthy hemisphere in the compensation for stroke-induced, chronic neuropsychological deficits, and suggest that prism adaptation can foster this role by exploiting sensorimotor/prefrontal circuits, especially when applied at early stages post-stroke.

scholarly journals Induced sensorimotor cortex plasticity remediates chronic treatment-resistant visual neglect

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Jacinta O'Shea ◽  
Patrice Revol ◽  
Helena Cousijn ◽  
Jamie Near ◽  
Pierre Petitet ◽  
...  
Keyword(s):  
Brain Injury ◽  
Case Series ◽  
Treatment Resistance ◽  
Prism Adaptation ◽  
Cognitive State ◽  
Visual Neglect ◽  
After Effects ◽  
Plastic Potential ◽  
Injury Causes

Right brain injury causes visual neglect - lost awareness of left space. During prism adaptation therapy, patients adapt to a rightward optical shift by recalibrating right arm movements leftward. This can improve left neglect, but the benefit of a single session is transient (~1 day). Here we show that tonic disinhibition of left motor cortex during prism adaptation enhances consolidation, stabilizing both sensorimotor and cognitive prism after-effects. In three longitudinal patient case series, just 20 min of combined stimulation/adaptation caused persistent cognitive after-effects (neglect improvement) that lasted throughout follow-up (18–46 days). Moreover, adaptation without stimulation was ineffective. Thus stimulation reversed treatment resistance in chronic visual neglect. These findings challenge consensus that because the left hemisphere in neglect is pathologically over-excited it ought to be suppressed. Excitation of left sensorimotor circuits, during an adaptive cognitive state, can unmask latent plastic potential that durably improves resistant visual attention deficits after brain injury.

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