scholarly journals Intrinsic medial temporal lobe connectivity relates to individual differences in episodic autobiographical remembering

Cortex ◽  
2016 ◽  
Vol 74 ◽  
pp. 206-216 ◽  
Author(s):  
Signy Sheldon ◽  
Norman Farb ◽  
Daniela J. Palombo ◽  
Brian Levine
Keyword(s):  
Individual Differences ◽  
Temporal Lobe ◽  
Medial Temporal Lobe

scholarly journals Individual differences in neurocognitive aging of the medial temporal lobe

AGE ◽  
2006 ◽  
Vol 28 (3) ◽  
pp. 221-233 ◽  
Author(s):  
Michela Gallagher ◽  
Carlo Colantuoni ◽  
Howard Eichenbaum ◽  
Rebecca P. Haberman ◽  
Peter R. Rapp ◽  
...  
Keyword(s):  
Individual Differences ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Neurocognitive Aging

scholarly journals Medial temporal lobe BOLD activity at rest predicts individual differences in memory ability in healthy young adults

2008 ◽  
Vol 105 (47) ◽  
pp. 18555-18560 ◽  
Author(s):  
G. S. Wig ◽  
S. T. Grafton ◽  
K. E. Demos ◽  
G. L. Wolford ◽  
S. E. Petersen ◽  
...  
Keyword(s):  
Young Adults ◽  
Individual Differences ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Memory Ability

scholarly journals Neural and behavioral correlates of episodic memory are associated with temporal discounting in older adults

2019 ◽  
Author(s):  
Karolina M. Lempert ◽  
Dawn J. Mechanic-Hamilton ◽  
Long Xie ◽  
Laura E.M. Wisse ◽  
Robin de Flores ◽  
...  
Keyword(s):  
Older Adults ◽  
Individual Differences ◽  
Episodic Memory ◽  
Temporal Lobe ◽  
Cortical Thickness ◽  
Medial Temporal Lobe ◽  
Structural Integrity ◽  
Temporal Discounting ◽  
Risk Tolerance ◽  
Trade Offs

AbstractWhen facing decisions involving trade-offs between smaller, sooner and larger, delayed rewards, people tend to discount the value of future rewards. There are substantial individual differences in this tendency toward temporal discounting, however. One neurocognitive system that may underlie these individual differences is episodic memory, given the overlap in the neural circuitry involved in imagining the future and remembering the past. Here we tested this hypothesis in older adults, including both those that were cognitively normal and those with amnestic mild cognitive impairment (MCI). We found that performance on neuropsychological measures of episodic memory retrieval was associated with temporal discounting, such that people with better memory discounted delayed rewards less. This relationship was specific to episodic memory and temporal discounting, since executive function (another cognitive ability) was unrelated to temporal discounting, and episodic memory was unrelated to risk tolerance (another decision-making preference). We also examined cortical thickness and volume in medial temporal lobe regions critical for episodic memory. Entorhinal cortical thickness was associated with reduced temporal discounting, with episodic memory performance partially mediating this association. The inclusion of MCI participants was critical to revealing these associations between episodic memory and entorhinal cortical thickness and temporal discounting. These effects were larger in the MCI group, reduced after controlling for MCI status, and statistically significant only when including MCI participants in analyses. Overall, these findings suggest that individual differences in temporal discounting are driven by episodic memory function, and that a decline in medial temporal lobe structural integrity may impact temporal discounting.

scholarly journals Individual differences in theta-band oscillations in a spatial memory network revealed by electroencephalography predict rapid place learning

2021 ◽  
Vol 5 ◽  
pp. 239821282110027
Author(s):  
Markus Bauer ◽  
Matthew G. Buckley ◽  
Tobias Bast
Keyword(s):  
Individual Differences ◽  
Spatial Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Place Learning ◽  
Theta Band ◽  
Delayed Matching ◽  
Place Task ◽  
The Right ◽  
Encoding And Retrieval

Spatial memory has been closely related to the medial temporal lobe and theta oscillations are thought to play a key role. However, it remains difficult to investigate medial temporal lobe activation related to spatial memory with non-invasive electrophysiological methods in humans. Here, we combined the virtual delayed-matching-to-place task, reverse-translated from the watermaze delayed-matching-to-place task in rats, with high-density electroencephalography recordings. Healthy young volunteers performed this computerised task in a virtual circular arena, which contained a hidden target whose location moved to a new place every four trials, allowing the assessment of rapid memory formation. Using behavioural measures as predictor variables for source reconstructed frequency-specific electroencephalography power, we found that inter-individual differences in ‘search preference’ during ‘probe trials’, a measure of one-trial place learning known from rodent studies to be particularly hippocampus-dependent, correlated predominantly with distinct theta-band oscillations (approximately 7 Hz), particularly in the right temporal lobe, the right striatum and inferior occipital cortex or cerebellum. This pattern was found during both encoding and retrieval/expression, but not in control analyses and could not be explained by motor confounds. Alpha-activity in sensorimotor and parietal cortex contralateral to the hand used for navigation also correlated (inversely) with search preference. This latter finding likely reflects movement-related factors associated with task performance, as well as a frequency difference in (ongoing) alpha-rhythm for high-performers versus low-performers that may contribute to these results indirectly. Relating inter-individual differences in ongoing brain activity to behaviour in a continuous rapid place-learning task that is suitable for a variety of populations, we could demonstrate that memory-related theta-band activity in temporal lobe can be measured with electroencephalography recordings. This approach holds great potential for further studies investigating the interactions within this network during encoding and retrieval, as well as neuromodulatory impacts and age-related changes.

Children show adult-like hippocampal pattern separation for familiar but not novel events

2020 ◽  
Author(s):  
Susan L. Benear ◽  
Elizabeth A. Horwath ◽  
Emily Cowan ◽  
M. Catalina Camacho ◽  
Chi Ngo ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Developmental Change ◽  
Pattern Separation ◽  
Developmental Changes ◽  
Similarity Analysis ◽  
Separation Processes ◽  
Parahippocampal Cortex ◽  
Pattern Similarity

The medial temporal lobe (MTL) undergoes critical developmental change throughout childhood, which aligns with developmental changes in episodic memory. We used representational similarity analysis to compare neural pattern similarity for children and adults in hippocampus and parahippocampal cortex during naturalistic viewing of clips from the same movie or different movies. Some movies were more familiar to participants than others. Neural pattern similarity was generally lower for clips from the same movie, indicating that related content taxes pattern separation-like processes. However, children showed this effect only for movies with which they were familiar, whereas adults showed the effect consistently. These data suggest that children need more exposures to stimuli in order to show mature pattern separation processes.

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