Temporal coupling due to illusory movements in bimanual actions: Evidence from anosognosia for hemiplegia

Cortex ◽  
2013 ◽  
Vol 49 (6) ◽  
pp. 1694-1703 ◽  
Author(s):  
Lorenzo Pia ◽  
Lucia Spinazzola ◽  
Marco Rabuffetti ◽  
Maurizio Ferrarin ◽  
Francesca Garbarini ◽  
...  
2010 ◽  
Vol 48 (12) ◽  
pp. 3443-3450 ◽  
Author(s):  
Catherine Preston ◽  
Paul M. Jenkinson ◽  
Roger Newport

1993 ◽  
Vol 264 (5) ◽  
pp. E776-E781 ◽  
Author(s):  
A. D. Genazzani ◽  
F. Petraglia ◽  
C. Volpogni ◽  
G. D'Ambrogio ◽  
F. Facchinetti ◽  
...  

Pulsatile secretion of gonadotropin was investigated in amenorrheic patients and in fertile and postmenopausal women to assess both follicle-stimulating hormone (FSH) episodic secretion and its temporal coupling with luteinizing hormone (LH). Three groups of amenorrheic patients were studied: hyperandrogenic (n = 20), hypogonadotropic (n = 51), and normogonadotropic (n = 31). Nineteen fertile women (during the follicular and luteal phases of the cycle) and sixteen postmenopausal women were investigated as reference groups. All subjects demonstrated the presence of a distinct pulsatile pattern with LH and FSH pulses/4 h as follows: hyperandrogenic 3.95 +/- 0.26 and 3.85 +/- 0.2, hypogonadotropic 3.76 +/- 0.26 and 3.9 +/- 0.16, normogonadotropic 3.5 +/- 0.2 and 3.9 +/- 0.17 LH and FSH pulses/4 h, respectively (means +/- SE). Normal controls showed 4.1 +/- 0.2 and 3.1 +/- 0.2 pulses/4 h for LH (P < 0.05) and 3.2 +/- 0.1 and 3.6 +/- 0.3 pulses/4 h for FSH, during follicular and luteal phases, respectively. Postmenopausal women showed 3.6 +/- 0.2 and 3.0 +/- 0.3 pulses/4 h for LH and FSH, respectively. Specific concordance (SC) index demonstrated that LH and FSH were significantly and simultaneously secreted in all groups. Conversely, LH and FSH were not temporally related during the luteal phase. In conclusion, we report a distinct FSH episodic secretion and its temporal linkage with LH pulses irrespective of plasma concentrations of gonadal steroids in secondary amenorrhea.


Author(s):  
Zhi Yao ◽  
Revathi Jambunathan ◽  
Yadong Zeng ◽  
Andrew Nonaka

We present a high-performance coupled electrodynamics–micromagnetics solver for full physical modeling of signals in microelectronic circuitry. The overall strategy couples a finite-difference time-domain approach for Maxwell’s equations to a magnetization model described by the Landau–Lifshitz–Gilbert equation. The algorithm is implemented in the Exascale Computing Project software framework, AMReX, which provides effective scalability on manycore and GPU-based supercomputing architectures. Furthermore, the code leverages ongoing developments of the Exascale Application Code, WarpX, which is primarily being developed for plasma wakefield accelerator modeling. Our temporal coupling scheme provides second-order accuracy in space and time by combining the integration steps for the magnetic field and magnetization into an iterative sub-step that includes a trapezoidal temporal discretization for the magnetization. The performance of the algorithm is demonstrated by the excellent scaling results on NERSC multicore and GPU systems, with a significant (59×) speedup on the GPU using a node-by-node comparison. We demonstrate the utility of our code by performing simulations of an electromagnetic waveguide and a magnetically tunable filter.


2021 ◽  
Author(s):  
Sahba Besharati ◽  
Paul Jenkinson ◽  
Michael Kopelman ◽  
Mark Solms ◽  
Valentina Moro ◽  
...  

In recent decades, the research traditions of (first-person) embodied cognition and of (third-person) social cognition have approached the study of self-awareness with relative independence. However, neurological disorders of self-awareness offer a unifying perspective to empirically investigate the contribution of embodiment and social cognition to self-awareness. This study focused on a neuropsychological disorder of bodily self-awareness following right-hemisphere damage, namely anosognosia for hemiplegia (AHP). A previous neuropsychological study has shown AHP patients, relative to neurological controls, to have a specific deficit in third-person, allocentric inferences in a story-based, mentalisation task. However, no study has tested directly whether verbal awareness of motor deficits is influenced by either perspective-taking or centrism, and if these deficits in social cognition are correlated with damage to anatomical areas previously linked to mentalising, including the supramarginal and superior temporal gyri and related limbic white matter connections. Accordingly, two novel experiments were conducted with right-hemisphere stroke patients with (n = 17) and without AHP (n = 17) that targeted either their own (egocentric, experiment 1) or another stooge patient’s (experiment 2) motor abilities from a first-or-third person (allocentric in Experiment 2) perspective. In both experiments, neurological controls showed no significant difference between perspectives, suggesting that perspective-taking deficits are not a general consequence of right-hemisphere damage. More specifically, experiment 1 found AHP patients were more aware of their own motor paralysis when asked from a third compared to a first-person perspective, using both group level and individual level analysis. In experiment 2, AHP patients were less accurate than controls in making allocentric, third-person perspective judgements about the stooge patient, but with only a trend towards significance and with no within-group, difference between perspectives. Deficits in egocentric and allocentric third-person perspective taking were associated with lesions in the middle frontal gyrus, superior temporal and supramarginal gyri, with white matter disconnections more predominate in deficits in allocentricity. This study confirms previous clinical and empirical investigations on the selectivity of first-person motor awareness deficits in anosognosia for hemiplegia and experimentally demonstrates for the first time that verbal egocentric 3PP-taking can positively influence 1PP body awareness.


IDEA JOURNAL ◽  
2020 ◽  
Vol 17 (02) ◽  
pp. 289-325
Author(s):  
Elly Clarke

At the 2019 Body of Knowledge Conference at Deakin University, I presented the third episode of performance-lecture series ‘Is My Body Out of Date?’ in collaboration with Melbourne-based artists Bon Mott and Sean Miles. Punctuated by quotes and phrases from a range of theorists, writers and artists including Karen Barad, Caroline Bassett, Laboria Cuboniks, Ian McEwan, Oscar Wilde, Yon Heong Tung, ETA Hoffman, Gilbert Simondon, and my drag character #Sergina, the performance (struck) poses (around) the question of whether, in a world that is increasingly managed and experienced online, our bodies, as our primary mode of interaction, may be beginning to feel out of date. Is our desire for sweaty, messy, fleshy physical co-presence out of whack with the agility, efficiency and value of our algorithms? Performed live at a laptop with Mott and Miles as physical #BackupBodies for my own body that didn’t fly from London for ecological reasons, this physical/digital screenshare performance wove in video documentation from previous #Sergina performances in order to confuse and conflate what was happening now, and what already happened, what was live and what was pre-recorded. Here we played with issues of perception, presence, liveness and the fantasy of the (ex)changeability of identity and ‘drag’ (performance) of physicality within an ever-shifting media present. What follows is a visual essay constructed out of the digital remnants of the performance: a (trans)script, a screen recording, screenshots and links to media located beyond the template of the text. The visual essay touches on key conference themes such as virtual embodiment, human/computer interaction, temporal coupling and time consciousness, knowledge-transfer and how technology affects the way we move, think and desire. Furthermore, the templates of Zoom video communications, of the laptop screen, of Chrome and the wider digital/physical conference model that hosted, directed (and dictated) the boundaries of our presentation reflect on the influence of design, layout and digit/al choreographies on the shaping and ordering of thought, knowledge and embodiment.


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