The impacts of elevated autism spectrum disorder traits on clinical and psychosocial features and long-term treatment outcome in adult patients with obsessive-compulsive disorder

2014 ◽  
Vol 55 (7) ◽  
pp. 1526-1533 ◽  
Author(s):  
Hironori Mito ◽  
Naomi Matsuura ◽  
Keiitiro Mukai ◽  
Yoshinobu Yanagisawa ◽  
Akihiro Nakajima ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Treatment Outcome ◽  
Obsessive Compulsive Disorder ◽  
Autism Spectrum ◽  
Term Treatment ◽  
Spectrum Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Long Term Treatment

Weight Gain During Long-Term Treatment of Obsessive-Compulsive Disorder

2004 ◽  
Vol 65 (10) ◽  
pp. 1365-1371 ◽  
Author(s):  
Giuseppe Maina ◽  
Umberto Albert ◽  
Virginio Salvi ◽  
Filippo Bogetto
Keyword(s):  
Weight Gain ◽  
Obsessive Compulsive Disorder ◽  
Term Treatment ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Long Term Treatment

Adapted cognitive behavior therapy for obsessive–compulsive disorder with co-occurring autism spectrum disorder: A clinical effectiveness study

Autism ◽  
2019 ◽  
Vol 24 (1) ◽  
pp. 190-199
Author(s):  
Oskar Flygare ◽  
Erik Andersson ◽  
Helene Ringberg ◽  
Anna-Clara Hellstadius ◽  
Johan Edbacken ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Obsessive–compulsive disorder and autism spectrum disorder commonly co-occur. Adapted cognitive behavior therapy for obsessive–compulsive disorder in adults with autism spectrum disorder has not previously been evaluated outside the United Kingdom. In this study, 19 adults with obsessive–compulsive disorder and autism spectrum disorder were treated using an adapted cognitive behavior therapy protocol that consisted of 20 sessions focused on exposure with response prevention. The primary outcome was the clinician-rated Yale–Brown Obsessive–Compulsive Scale. Participants were assessed up to 3 months after treatment. There were significant reductions on the Yale–Brown Obsessive–Compulsive Scale at post-treatment (d = 1.5), and improvements were sustained at follow-up (d = 1.2). Self-rated obsessive–compulsive disorder and depressive symptoms showed statistically significant reductions. Improvements in general functioning and quality of life were statistically non-significant. Three participants (16%) were responders at post-treatment and four (21%) were in remission from obsessive–compulsive disorder. At follow-up, three participants (16%) were responders and one (5%) was in full remission. Adapted cognitive behavior therapy for obsessive–compulsive disorder in adults with co-occurring autism spectrum disorder is associated with reductions in obsessive–compulsive symptoms and depressive symptoms. However, outcomes are modest; few patients were completely symptom free, and treatment engagement was low with few completed exposures and low adherence to homework assignments. We identify and discuss the need for further treatment refinement for this vulnerable group.

A Case Report of Intensive Exposure-Based Cognitive Behavioral Therapy for a Child With Comorbid Autism Spectrum Disorder and Obsessive-Compulsive Disorder

2017 ◽  
Vol 31 (2) ◽  
pp. 118-123
Author(s):  
Katie L. Merricks ◽  
Joshua M. Nadeau ◽  
Amaya Ramos ◽  
Eric A. Storch
Keyword(s):  
Autism Spectrum Disorder ◽  
Cognitive Behavioral Therapy ◽  
Obsessive Compulsive Disorder ◽  
Treatment Modality ◽  
Behavioral Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Cognitive Behavioral ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Cognitive behavioral therapy (CBT) with exposure and response prevention (ERP) has proven to be an effective treatment modality for children with obsessive-compulsive disorder (OCD). Less research exists demonstrating efficacy for this treatment modality among children with comorbid diagnoses of OCD and autism spectrum disorder (ASD), and virtually, nothing has been reported examining intensive interventions for the most severe cases. As such, this article discusses the treatment of an adolescent male with severe OCD comorbid with ASD, attention deficit hyperactivity disorder (ADHD), generalized anxiety disorder (GAD), and chronic tic disorder using a cognitive behavioral approach and ERP. We conclude with recommendations for continued clinical research to understand approaches to help nonresponders to standard therapeutic approaches with this challenging population.

scholarly journals Co‑occurring Obsessive‑compulsive Disorder, Autism Spectrum Disorder and Intellectual Disability: A Case Report

2021 ◽  
pp. 31-34
Author(s):  
Márcia Rodrigues ◽  
Alexandre Gomes ◽  
Emanuel Santos ◽  
Zélia Figueiredo
Keyword(s):  
Autism Spectrum Disorder ◽  
Intellectual Disability ◽  
Obsessive Compulsive Disorder ◽  
Behavioral Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Integrative Approach ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Wide Range

Autism spectrum disorders encompass a wide range of clinical presentations, including obsessive‑compulsive symptoms. The comorbidity between these disorders is significant, and it has therapeutic and prognostic implications. While there are a few references on the approach of such comorbid presentations, the literature is even scarcer when this co‑occurrence is superimposed on individuals with intellectual disability. We present the case of a 43‑years‑old male patient with comorbid treatment refractory obsessive‑compulsive disorder, autism spectrum disorder and intellectual disability, exhibiting subacute symptomatic recurrence including hetero‑aggressive outbursts and contamination obsessions. The phenomenological features and therapeutic strategies are discussed, highlighting the centrality of a patient‑centered and methodologically pluralistic approach. Symptomatic remission was achieved employing high end doses of fluvoxamine and haloperidol, alongside daily psychotherapy involving both symptom‑directed behavioral therapy and supportive psychodynamic techniques. An integrative approach may be the best option in the stabilization of complex cases as the one presented.

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