Stressful life events and relationships are associated with mental health symptoms and substance use in young adolescents

2011 ◽  
Vol 52 (6) ◽  
pp. e10
Author(s):  
N.C. Low ◽  
E. Dugas ◽  
D. Rodriguez ◽  
G. Contreras ◽  
E. O'Loughlin ◽  
...  
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Young Adolescents ◽  
Mental Health Symptoms ◽  
Health Symptoms

scholarly journals Common stressful life events and difficulties are associated with mental health symptoms and substance use in young adolescents

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Nancy CP Low ◽  
Erika Dugas ◽  
Erin O’Loughlin ◽  
Daniel Rodriguez ◽  
Gisele Contreras ◽  
...  
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Young Adolescents ◽  
Mental Health Symptoms ◽  
Health Symptoms

scholarly journals Substance use, stressful life events and mental health: A longitudinal study among homeless women in Madrid (Spain)

2020 ◽  
Vol 103 ◽  
pp. 106246 ◽  
Author(s):  
Ana I. Guillén ◽  
Carolina Marín ◽  
Sonia Panadero ◽  
José Juan Vázquez
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Longitudinal Study ◽  
Life Events ◽  
Stressful Life Events ◽  
Homeless Women ◽  
Stressful Life

scholarly journals A learning algorithm for predicting mental health symptoms and substance use

2021 ◽  
Vol 134 ◽  
pp. 22-29
Author(s):  
Anthony T. Fojo ◽  
Catherine R. Lesko ◽  
Kelly S. Benke ◽  
Geetanjali Chander ◽  
Bryan Lau ◽  
...  
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Learning Algorithm ◽  
Mental Health Symptoms ◽  
Health Symptoms

The relations between discrimination, stressful life events, and substance use among adults experiencing homelessness

2021 ◽  
Author(s):  
Adam C. Alexander ◽  
Joseph J.C. Waring ◽  
Oluwakemi Olurotimi ◽  
Jasmin Kurien ◽  
Bishop Noble ◽  
...  
Keyword(s):  
Substance Use ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life

PP21  Perceptions and experiences of employee mental health support: a cross-sectional survey of UK ambulance service staff

2020 ◽  
Vol 37 (10) ◽  
pp. e10.2-e10
Author(s):  
Sasha Johnston ◽  
Jennifer Wild ◽  
Kristy Sanderson ◽  
Bridie Kent
Keyword(s):  
Mental Health ◽  
Sickness Absence ◽  
Life Events ◽  
Symptom Severity ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Event Scale ◽  
Work Related ◽  
Organisational Support ◽  
Service Staff

BackgroundMental ill health among ambulance staff is widespread. Evidence suggests that, with the right support, staff experiencing mental ill health can continue to work, symptom severity can be reduced and suicide prevented. To identify whether organisational support meets staff needs, this research explored the perceptions and experiences of staff working in a large ambulance trust covering the south west of England.MethodsBetween September and October 2018, ambulance staff were invited to complete an online questionnaire, which assessed demographics, work-related stressful life events, related psychological impact assessed by the avoidant subscale of Weiss and Marmar’s Impact of Event Scale-Revised, mental ill health sickness absence during the previous 12 months, perceptions and experiences of organisational support and acceptability of a proposed wellbeing intervention offering mandatory time-to-talk at work.ResultsOver 11% (N=540) of the workforce responded. The majority reported experiencing work-related stressful life events (n=444; 82%), that were associated with subsequent avoidant symptoms. Avoidant symptom severity peaked between six-months to five-years after an event (F (5,438) = 2.4, p=0.03), was associated with repeated exposure (F (4,439) = 2.9, p=0.01) and to sickness absence. A fifth of participants reported mental ill health sickness absence (21.6%), a third of which was not disclosed as related to mental health. Content analysis identified stigma, fear, as well as embarrassment, as barriers to disclosure and help-seeking. Perceptions and experiences of organisational support were significantly correlated (r (195) =0.46, p<0.001) and positive.ConclusionsSymptoms associated with work-related stressful life events can persist for years among ambulance staff. Given the association between organisational support and mental wellbeing, it is possible that an intervention, such as mandatory time-to-talk, supported at an organisation level could improve wellbeing among ambulance staff. Such an intervention needs to be evaluated in future research.

scholarly journals Infant birthweight in the US: the role of preconception stressful life events and substance use

2016 ◽  
Vol 19 (3) ◽  
pp. 529-542 ◽  
Author(s):  
Whitney P. Witt ◽  
Kara C. Mandell ◽  
Lauren E. Wisk ◽  
Erika R. Cheng ◽  
Debanjana Chatterjee ◽  
...  
Keyword(s):  
Substance Use ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
The Us

A functional neuregulin-1 gene variant and stressful life events: Effect on drug use in a longitudinal population-representative cohort study

2016 ◽  
Vol 31 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Mariliis Vaht ◽  
Kariina Laas ◽  
Evelyn Kiive ◽  
Jüri Parik ◽  
Toomas Veidebaum ◽  
...  
Keyword(s):  
Substance Use ◽  
Drug Use ◽  
Life Events ◽  
Illicit Drugs ◽  
Substance Dependence ◽  
Stressful Life Events ◽  
Susceptibility Gene ◽  
Stressful Life ◽  
Health Study ◽  
Neuregulin 1

Background: The neuregulin 1 gene is a susceptibility gene for substance dependence. A functional polymorphism (SNP8NRG243177/rs6994992; C/T) in the promoter region of the brain-specific type IV neuregulin-1 gene ( NRG1) has been associated with psychiatric disorders (e.g. schizophrenia and bipolar disorder) that often present higher odds of smoking, alcohol and illicit drug use. This study assessed the association of the NRG1 genotype with drug use and possible interaction with stressful life events (SLEs). Methods: The database of the Estonian Children Personality Behaviour and Health Study (beginning in 1998) was used. Cohorts of children initially 9 years old ( n=583; followed up at 15 and 18 years) and 15 years old ( n=593; followed up at 18 and 25 years) provided self-reports on alcohol, tobacco and illicit substance use and SLEs. Psychiatric assessment based on DSM-IV was carried out on the older birth cohort at age 25 to assess the lifetime presence of substance use disorders. NRG1 rs6994992 was genotyped in all participants by TaqMan® Pre-Designed SNP Genotyping Assay on the Applied Biosystems ViiA™ 7 Real-Time PCR System. The minor (T) allele frequency was 0.37. Results: NRG1 rs6994992 C/C homozygotes, especially those who had experienced more SLEs, were more likely to develop alcohol use disorders by young adulthood, were generally more active consumers of tobacco products, and had more likely used illicit drugs. In T allele carriers, SLEs had a negligible effect on substance use. Conclusions: In humans, NRG1 genotype is associated with substance use, and this relationship is moderated by adverse life events, with a gain-of-function allele being protective.

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