Molecular imaging of small animals with fluorescent proteins: From projection to multimodality

2012 ◽  
Vol 36 (4) ◽  
pp. 259-263 ◽  
Author(s):  
Xiaoquan Yang ◽  
Hui Gong ◽  
Jianwei Fu ◽  
Guotao Quan ◽  
Chuan Huang ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Fluorescent Proteins ◽  
Small Animals

scholarly journals Normalized Transillumination of Fluorescent Proteins in Small Animals

2006 ◽  
Vol 5 (3) ◽  
pp. 7290.2006.00018 ◽  
Author(s):  
Giannis Zacharakis ◽  
Helen Shih ◽  
Jorge Ripoll ◽  
Ralph Weissleder ◽  
Vasilis Ntziachristos
Keyword(s):  
Fluorescent Proteins ◽  
Small Animals

scholarly journals Photoacoustic reporter genes for noninvasive molecular imaging and theranostics

2020 ◽  
Vol 13 (03) ◽  
pp. 2030005
Author(s):  
Zhao Lei ◽  
Yun Zeng ◽  
Xiaofen Zhang ◽  
Xiaoyong Wang ◽  
Gang Liu
Keyword(s):  
Molecular Imaging ◽  
Fluorescent Proteins ◽  
Photoacoustic Imaging ◽  
High Sensitivity ◽  
Reporter Genes ◽  
Biological Processes ◽  
Deep Tissue ◽  
Potential Applications ◽  
Improved Performance

Noninvasive molecular imaging makes the observation and comprehensive understanding of complex biological processes possible. Photoacoustic imaging (PAI) is a fast evolving hybrid imaging technology enabling in vivo imaging with high sensitivity and spatial resolution in deep tissue. Among the various probes developed for PAI, genetically encoded reporters attracted increasing attention of researchers, which provide improved performance by acquiring images of a PAI reporter gene’s expression driven by disease-specific enhancers/promoters. Here, we present a brief overview of recent studies about the existing photoacoustic reporter genes (RGs) for noninvasive molecular imaging, such as the pigment enzyme reporters, fluorescent proteins and chromoproteins, photoswitchable proteins, including their properties and potential applications in theranostics. Furthermore, the challenges that PAI RGs face when applied to the clinical studies are also examined.

Dual-Modality Molecular Imaging for Small Animals Using Fluorescence and X-Ray Computed Tomography

2009 ◽  
Author(s):  
Yuting Lin ◽  
William C. Barber ◽  
Jan S. Iwanczk ◽  
Einar Nygard ◽  
Nail Malakov ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Molecular Imaging ◽  
Small Animals ◽  
X Ray ◽  
Dual Modality ◽  
X Ray Computed

scholarly journals Dosimetry for spectral molecular imaging of small animals with MARS-CT

2015 ◽  
Author(s):  
Noémie Ganet ◽  
Nigel Anderson ◽  
Stephen Bell ◽  
Anthony Butler ◽  
Phil Butler ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Small Animals
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