Self-assembled nanoparticles based on chondroitin sulfate-deoxycholic acid conjugates for docetaxel delivery: Effect of degree of substitution of deoxycholic acid

2016 ◽  
Vol 146 ◽  
pp. 235-244 ◽  
Author(s):  
Mengrui Liu ◽  
Hongliang Du ◽  
Guangxi Zhai
Keyword(s):  
Chondroitin Sulfate ◽  
Deoxycholic Acid ◽  
Degree Of Substitution ◽  
Self Assembled

Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel

Biomaterials ◽  
2012 ◽  
Vol 33 (7) ◽  
pp. 2310-2320 ◽  
Author(s):  
Jing Li ◽  
Meirong Huo ◽  
Jing Wang ◽  
Jianping Zhou ◽  
Jumah M. Mohammad ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Deoxycholic Acid ◽  
Intracellular Delivery ◽  
Self Assembled

Self-Assembled Networks of Ribbons in Molecular Hydrogels of Cationic Deoxycholic Acid Analogues

2005 ◽  
Vol 109 (25) ◽  
pp. 12270-12276 ◽  
Author(s):  
Pierre Terech ◽  
Neralagatta M. Sangeetha ◽  
Bruno Demé ◽  
Uday Maitra
Keyword(s):  
Deoxycholic Acid ◽  
Self Assembled

Effect of sophorolipid on the curcumin-loaded ternary composite nanoparticles self-assembled from zein and chondroitin sulfate

2021 ◽  
Vol 113 ◽  
pp. 106493
Author(s):  
Yongkai Yuan ◽  
Mengjie Ma ◽  
Shuaizhong Zhang ◽  
Chengzhen Liu ◽  
Peng Chen ◽  
...  
Keyword(s):  
Chondroitin Sulfate ◽  
Composite Nanoparticles ◽  
Ternary Composite ◽  
Self Assembled

scholarly journals Preparation and Characterization of Self-Assembled Nanoparticles of Hyaluronic Acid-Deoxycholic Acid Conjugates

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Xuemeng Dong ◽  
Chenguang Liu
Keyword(s):  
Hyaluronic Acid ◽  
Deoxycholic Acid ◽  
Structural Characteristics ◽  
Cetylpyridinium Chloride ◽  
Coupling Reaction ◽  
Critical Aggregation Concentration ◽  
Transmission Electron ◽  
Fluorescence Quenching Method ◽  
Self Assembled ◽  
Quenching Method

Novel amphiphilic biopolymers were synthesized using hyaluronic acid (HA) as a hydrophilic segment and deoxycholic acid (DOCA) as a hydrophobic segment by a 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide mediated coupling reaction. The structural characteristics of the HA-DOCA conjugates were investigated usingH1NMR. Self-assembled nanoparticles were prepared based on HA-DOCA conjugates, and its characteristics were investigated using dynamic laser light scattering, transmission electron microscopy (TEM), and fluorescence spectroscopy. The mean diameter was about 293.5 nm with unimodal size distribution in distilled water. The TEM images revealed that the shape of HA-DOCA self-aggregates was spherical. The critical aggregation concentration (CAC) was in the range of 0.025–0.056 mg/mL. The partition equilibrium constant (Kv) of pyrene in self-aggregates solution was from1.45×104to3.64×104. The aggregation number of DOCA groups per hydrophobic microdomain, estimated by the fluorescence quenching method using cetylpyridinium chloride, increased with increasing degree of substitution.

Novel self-assembled amphiphilic mPEGylated starch-deoxycholic acid polymeric micelles with pH-response for anticancer drug delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (98) ◽  
pp. 55139-55149 ◽  
Author(s):  
Jinlong Yang ◽  
Chunmei Gao ◽  
Shaoyu Lü ◽  
Xinggang Wang ◽  
Mingjia Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Deoxycholic Acid ◽  
Polymeric Micelles ◽  
Anticancer Drug Delivery ◽  
Ph Response ◽  
Self Assembled
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