Thermosensitive silica-pluronic-starch model coating dispersion-part I: The effect of Pluronic block copolymer adsorption on the colloidal stability and rheology

Author(s):  
Yana Petkova-Olsson ◽  
Henrik Ullsten ◽  
Lars Järnström
2009 ◽  
Vol 329 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Gemma E. Newby ◽  
Ian W. Hamley ◽  
Stephen M. King ◽  
Christopher M. Martin ◽  
Nicholas J. Terrill

Langmuir ◽  
2010 ◽  
Vol 26 (7) ◽  
pp. 5153-5159 ◽  
Author(s):  
Timur I. Abdullin ◽  
Oxana V. Bondar ◽  
Yu. G. Shtyrlin ◽  
Mehmet Kahraman ◽  
Mustafa Culha

Soft Matter ◽  
2013 ◽  
Vol 9 (11) ◽  
pp. 3050 ◽  
Author(s):  
Hyung-Sik Jang ◽  
Tae-Hwan Kim ◽  
Changwoo Do ◽  
Min-Jae Lee ◽  
Sung-Min Choi

Author(s):  
Rashmi Seneviratne ◽  
Lars J.C. Jeuken ◽  
Michael Rappolt ◽  
Paul A. Beales

Sterilisation and preservation of vesicle formulations are an important consideration for their viable manufacture for industry applications, particular those intended for medicinal use. Here we undertake an initial investigation of the stability of hybrid lipid – block copolymer vesicles to common sterilisation and preservation processes, with particular interest in how the block copolymer component might tune vesicle stability. We investigate two sizes of polybutadiene-block-poly(ethylene oxide) polymers (PBd12-PEO11 and PBd22-PEO14) mixed with the phospholipid POPC considering the encapsulation stability of a fluorescent cargo and the colloidal stability of vesicle size distributions. We find that autoclaving and lyophilisation cause complete loss of encapsulation stability under the conditions studied here. Filtering through 200 nm pores appears to be viable for sterilisation for all vesicle compositions with comparatively low release of encapsulated cargo, even for vesicle size distributions which extend beyond the 200 nm filter pore size. Freeze-thaw of vesicles also shows promise for preservation of hybrid vesicles with high block copolymer content. We discuss the process stability of hybrid vesicles in terms of the complex mechanical interplay between bending resistance, stretching elasticity and lysis strain of these membranes and propose strategies for future work to further enhance the process stability of these vesicle formulations.


2017 ◽  
Vol 8 (31) ◽  
pp. 4528-4537 ◽  
Author(s):  
Eunyong Seo ◽  
Sang-Ho Lee ◽  
Sangho Lee ◽  
Soo-Hyung Choi ◽  
Craig J. Hawker ◽  
...  

We herein report a facile synthetic method for preparing gold nanoparticles (Au NPs) with superior colloidal stability using a series of double hydrophilic block copolymers (DHBC), poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA), as a template (Au@DHBC NPs).


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