Generating psychotropic drug exposure data from computer-based medical records

2006 ◽  
Vol 83 (2) ◽  
pp. 120-124 ◽  
Author(s):  
Chiara Bonetto ◽  
Michela Nosè ◽  
Corrado Barbui
Keyword(s):  
Psychotropic Drug ◽  
Medical Records ◽  
Drug Exposure ◽  
Exposure Data ◽  
Computer Based

Fetal Minoxidil Exposure

PEDIATRICS ◽  
1987 ◽  
Vol 80 (1) ◽  
pp. 120-120
Author(s):  
FRANZ W. ROSA ◽  
JUHANA IDANPAAN-HEIKKILA ◽  
RITA ASANTI
Keyword(s):  
Case Report ◽  
Drug Administration ◽  
Birth Defects ◽  
Drug Safety ◽  
Congenital Anomalies ◽  
Drug Exposure ◽  
Spontaneous Abortions ◽  
Multiple Congenital Anomalies ◽  
Exposure Data ◽  
National Drug

To the Editor.— Kaler et al (Pediatrics 1987;79:434-436) provided a case report of hypertrichosis and multiple congenital anomalies with maternal minoxidil use. Reports such as this contribute to alerting national drug safety offices of possible teratologic questions. Maternal drug exposure data, since 1979 when minoxidil was marketed, is available to the Food and Drug Administration (FDA) from 73,000 pregnancies (15,600 birth defects, 4,400 spontaneous abortions, and 53,000 normal outcomes). This yields, in addition to the report by Kaler et al, only two other births with maternal minoxidil exposures:

Comparison of Prescription and Medical Records in Reflecting Patient Antihypertensive Drug Therapy

1994 ◽  
Vol 28 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Dale B. Christensen ◽  
Barbara Williams ◽  
Harold I. Goldberg ◽  
Diane P. Martin ◽  
Ruth Engelberg ◽  
...  
Keyword(s):  
Medical Record ◽  
Medical Records ◽  
Health Maintenance Organizations ◽  
Antihypertensive Drug Therapy ◽  
Antihypertensive Medications ◽  
Pharmacy Records ◽  
Health Maintenance ◽  
Computer Based ◽  
High Level ◽  
Level Of Agreement

OBJECTIVE: To determine the completeness of prescription records, and the extent to which they agreed with medical record drug entries for antihypertensive medications. SETTING: Three clinics affiliated with two staff model health maintenance organizations (HMOs). PARTICIPANTS: Randomly selected HMO enrollees (n=982) with diagnosed hypertension. METHODS: Computer-based prescription records for antihypertensive medications were reviewed at each location using an algorithm to convert the directions-for-use codes into an amount to be consumed per day (prescribed daily dosage). The medical record was analyzed similarly for the presence of drug notations and directions for use. RESULTS: There was a high level of agreement between the medical record and prescription file with respect to identifying the drug prescribed by drug name. Between 5 and 14 percent of medical record drug entries did not have corresponding prescription records, probably reflecting patient decisions not to have prescriptions filled at HMO-affiliated pharmacies or at all. Further, 5–8 percent of dispensed prescription records did not have corresponding medical record drug entry notations, probably reflecting incomplete recording of drug information on the medical record. The percentage of agreement of medical records on dosage ranged from 68 to 70 percent across two sites. Approximately 14 percent of drug records at one location and 21 percent of records at the other had nonmatching dosage information, probably reflecting dosage changes noted on the medical record but not reflected on pharmacy records. CONCLUSIONS: In the sites studied, dispensed prescription records reasonably reflect chart drug entries for drug name, but not necessarily dosage.

scholarly journals Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies

2018 ◽  
Vol 27 (7) ◽  
pp. 781-788 ◽  
Author(s):  
Stephen R. Pye ◽  
Thérèse Sheppard ◽  
Rebecca M. Joseph ◽  
Mark Lunt ◽  
Nadyne Girard ◽  
...  
Keyword(s):  
Drug Exposure ◽  
Exposure Data

scholarly journals Illegible Handwriting in Medical Records

2002 ◽  
Vol 95 (11) ◽  
pp. 545-546 ◽  
Author(s):  
F Javier Rodríguez-Vera ◽  
Y Marín ◽  
A Sánchez ◽  
C Borrachero ◽  
E Pujol
Keyword(s):  
General Hospital ◽  
Medical Records ◽  
Representative Sample ◽  
Computer Based ◽  
Clinical Records

In clinical records many items are handwritten and difficult to read. We examined clinical histories in a representative sample of case notes from a Spanish general hospital. Two independent observers assigned legibility scores, and a third adjudicated in case of disagreement. Defects of legibility such that the whole was unclear were present in 18 (15%) of 117 reports, and were particularly frequent in records from surgical departments. Through poor handwriting, much information in medical records is inaccessible to auditors, to researchers, and to other clinicians involved in the patient's care. If clinicians cannot be persuaded to write legibly, the solution must be an accelerated switch to computer-based systems.

Evaluating the introduction of a computerized prior-authorization system on the completeness of drug exposure data

2013 ◽  
Vol 22 (5) ◽  
pp. 551-555 ◽  
Author(s):  
John-Michael Gamble ◽  
Jeffrey A. Johnson ◽  
Sumit R. Majumdar ◽  
Finlay A. McAlister ◽  
Scot H. Simpson ◽  
...  
Keyword(s):  
Drug Exposure ◽  
Prior Authorization ◽  
Exposure Data

scholarly journals The Risk of Osteonecrosis of the Jaws in Taiwanese Osteoporotic Patients Treated With Oral Alendronate or Raloxifene

2014 ◽  
Vol 99 (8) ◽  
pp. 2729-2735 ◽  
Author(s):  
Wei-Yih Chiu ◽  
Jung-Yien Chien ◽  
Wei-Shiung Yang ◽  
Jyh-Ming Jimmy Juang ◽  
Jang-Jaer Lee ◽  
...  
Keyword(s):  
Electronic Medical Records ◽  
Medical Records ◽  
Drug Exposure ◽  
Independent Predictor ◽  
Contributing Factors ◽  
Taiwanese Population ◽  
Duration Of Treatment ◽  
Osteonecrosis Of The Jaws ◽  
Prevention Of Osteoporosis ◽  
Medical Records System

Background: This study aimed to explore the possible association between osteonecrosis of the jaws (ONJ) and oral alendronate or raloxifene used for osteoporosis and to estimate its absolute and attributable risks in the Taiwanese population. Methods: Using an electronic medical records system and manual confirmation of ONJ, we identified patients who began taking alendronate or raloxifene for osteoporosis and developed ONJ between January 2000 and April 2012. Results: The incidence of ONJ associated with oral alendronate for the management of osteoporosis began after 1 year of drug exposure and progressively increased with longer durations of therapy, specifically from 0.23% to 0.92% as the duration of treatment went from 2 years to 10 years. The overall frequency of ONJ related to oral alendronate over a 12-year period was 0.55%. The incidence rate of ONJ attributed to alendronate exposure was 283 per 100 000 persons per year. On multivariate Cox proportional analysis, adjusting for the potential confounders, alendronate remains an independent predictor for ONJ occurrence [hazard ratio 7.42 (1.02–54.09)] compared with raloxifene. Advanced age, drug duration, and coexisting diabetes and rheumatoid arthritis are contributing factors to the development of oral alendronate-related ONJ. Conclusion: We provided the evidence to support the association of ONJ with oral alendronate used in the treatment or prevention of osteoporosis.

Surveillance of Occupational Risks Using Job-Exposure Matrices

1991 ◽  
Vol 30 (02) ◽  
pp. 132-137 ◽  
Author(s):  
A. Mouaddib ◽  
C. Huy-Simon ◽  
P. Robaux ◽  
J. M. Martin
Keyword(s):  
Medical Records ◽  
Simple Structure ◽  
Health Data ◽  
Computer Assisted ◽  
Job Exposure Matrix ◽  
Occupational Risks ◽  
Exposure Data ◽  
Rectangular Arrays ◽  
Types Of Information ◽  
A Company

AbstractThis article deals with the problem of surveillance of occupational risks of workers. Computer-assisted elaboration of the job history (JH) for each worker was achieved by means of a job-exposure matrix (JEM) for each company. The final aim of the project is to find correlations between the exposure data of JHs and the health data of corresponding medical records.As a first experiment, some JEMs were computed using rectangular arrays even though it was realized that this simple structure was not really adequate. Later on, the structure of the computerized JEM included the following questions: (1) what types of information are involved; (2) how can the job-exposure correspondence be represented in the computer; (3) what characteristics of a company should be used for the elaboration of a JEM; (4) who is to construct each JEM, and how? This article shows the inadequacy of some occupational names for evoking the appropriate risks, a drawback which can be surmounted if the company organization is included in the JEM. Based on our analysis, several specifications useful for JEM computerization have been suggested.

A comparison of patient attitudes towards the use of computerised medical records and unique identifiers in Australia and Sweden

2004 ◽  
Vol 10 (2) ◽  
pp. 36
Author(s):  
David Bomba ◽  
Kurt Svardsudd ◽  
Per Kristiansson
Keyword(s):  
Health Care ◽  
Medical Records ◽  
Medical Information ◽  
Information Privacy ◽  
Patient Attitudes ◽  
Australian Study ◽  
Privacy And Security ◽  
Computer Based ◽  
Patient Consultation ◽  
Central Database

This article compares the attitudes of Australian and Swedish patients towards the use of computerised medical records and unique identifiers in medical practices in Australia and Sweden. A Swedish translation of an Australian survey was conducted and results were compared. Surveys were distributed to patients at a medical practice in Sweden in 2003 and compared to the results of an Australian study by Bomba and Land (2003). Results: Based on the survey samples (Australia N=271 and Sweden N=55), 91% of Swedish respondents and 78% of Australian respondents gave a positive appraisal of the use of computers in health care. Of the Swedish respondents, 93% agreed that the computer-based patient record is an essential technology for health care in the future, while 86% of the Australian respondents agreed. Overwhelmingly, 95% of Swedish respondents and 91% of Australian respondents stated that the use of computers did not interfere with the doctor-patient consultation. Both groups preferred biometric identification as the method for uniquely identifying patients but differed in their preferred method to store medical information - a combination of central database and smart card for Australian respondents and central database for Swedish respondents. This analysis indicates that patient attitudes towards the use of computerised medical records and unique identifiers in Australia and Sweden are positive; however, there are concerns over information privacy and security. These concerns need to be taken into account in any future development of a national computer health network.

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