Essential trace element status and clinical outcomes in long-term dialysis patients: A two-year prospective observational cohort study

2012 ◽  
Vol 31 (5) ◽  
pp. 630-636 ◽  
Author(s):  
Chih-Yu Yang ◽  
Ming-Ling Wu ◽  
Yea-Yun Chou ◽  
Szu-Yuan Li ◽  
Jou-Fang Deng ◽  
...  
Keyword(s):  
Cohort Study ◽  
Trace Element ◽  
Clinical Outcomes ◽  
Observational Cohort Study ◽  
Prospective Observational Cohort Study ◽  
Essential Trace Element ◽  
Dialysis Patients ◽  
Trace Element Status ◽  
Observational Cohort

scholarly journals Roxadustat in treating anemia in dialysis patients (ROAD): protocol and rationale of a multicenter prospective observational cohort study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yaling Zhang ◽  
Song Ren ◽  
Hen Xue ◽  
Amanda Y Wang ◽  
Yang Zou ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Outcomes ◽  
Cardiovascular Death ◽  
Observational Cohort Study ◽  
Major Adverse Cardiovascular Events ◽  
Dialysis Patients ◽  
All Cause Mortality ◽  
Observational Cohort ◽  
Prospective Longitudinal

Abstract Background Roxadustat has been shown effective in treating patients with anemia due to chronic kidney disease. However, its long-term effect on clinical outcomes and socioeconomic burden and safety remains unclear. Methods/Design This is a multicenter, prospective, longitudinal observational cohort study assessing if Roxadustat improves prognosis in dialysis patients. Primary outcomes will be major adverse cardiovascular events (MACE), defined as composites of cardiovascular death, myocardial infarction, cerebral infarction, hospitalization because of heart failure; all-cause mortality, and annual economic costs in two years. The data will be collected via Research electronic data capture (REDCap) based database as well as software-based dialysis registry of Sichuan province. The primary outcomes for the ROAD study participants will be compared with those in the dialysis registry cohort. Data at baseline and study follow up will also be compared to assess the association between Roxadustat and long-term clinical outcomes. Discussion The main objective of this study is to the assess long-term association of Roxadustat on MACE, all-cause mortality, socio-economic burden, safety in dialysis patients, which will provide guidance for designing further large randomized controlled trials to investigate this clinic question. Study registration The study has been registered in Chinese Clinical Trials Registry (ROAD, ROxadustat in treating Anemia in Dialysis patients, registration number ChiCTR1900025765) and provincial observational cohort database (Renal disEAse observational CoHort database, REACH, ChiCTR1900024926), registered 07 September 2019, http://www.chictr.org.cn.

scholarly journals Long-term follow-up for Psychological stRess in Intensive CarE (PRICE) survivors: study protocol for a multicentre, prospective observational cohort study in Australian intensive care units

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e023310
Author(s):  
Sumeet Rai ◽  
Rhonda Brown ◽  
Frank van Haren ◽  
Teresa Neeman ◽  
Arvind Rajamani ◽  
...  
Keyword(s):  
Cohort Study ◽  
Intensive Care ◽  
Family Members ◽  
Psychological Outcomes ◽  
Observational Cohort Study ◽  
Screening Tools ◽  
Prospective Observational Cohort Study ◽  
Observational Cohort

IntroductionThere are little published data on the long-term psychological outcomes in intensive care unit (ICU) survivors and their family members in Australian ICUs. In addition, there is scant literature evaluating the effects of psychological morbidity in intensive care survivors on their family members. The aims of this study are to describe and compare the long-term psychological outcomes of intubated and non-intubated ICU survivors and their family members in an Australian ICU setting.Methods and analysisThis will be a prospective observational cohort study across four ICUs in Australia. The study aims to recruit 150 (75 intubated and 75 non-intubated) adult ICU survivors and 150 family members of the survivors from 2015 to 2018. Long-term psychological outcomes and effects on health-related quality of life (HRQoL) will be evaluated at 3 and 12 months follow-up using validated and published screening tools. The primary objective is to compare the prevalence of affective symptoms in intubated and non-intubated survivors of intensive care and their families and its effects on HRQoL. The secondary objective is to explore dyadic relations of psychological outcomes in patients and their family members.Ethics and disseminationThe study has been approved by the relevant human research ethics committees (HREC) of Australian Capital Territory (ACT) Health (ETH.11.14.315), New South Wales (HREC/16/HNE/64), South Australia (HREC/15/RAH/346). The results of this study will be published in a peer-reviewed medical journal and presented to the local intensive care community and other stakeholders.Trial registration numberACTRN12615000880549; Pre-results.

scholarly journals The long-term postoperative trajectory of geriatric patients admitted for a hip fracture: A prospective observational cohort study

2020 ◽  
Vol 106 (4) ◽  
pp. 621-625 ◽  
Author(s):  
Philippe Beauchamp-Chalifour ◽  
Etienne L. Belzile ◽  
Louis-Charles Racine ◽  
Marie-Pier Nolet ◽  
Stéphane Lemire ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hip Fracture ◽  
Geriatric Patients ◽  
Observational Cohort Study ◽  
Prospective Observational Cohort Study ◽  
Observational Cohort
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