scholarly journals CAROTID PLAQUE VOLUME CHANGES OF STROKE AND TIA PATIENTS IN SIX MONTH FOLLOW-UP PERIOD: OBSERVATIONAL STUDY WITH NEW THREE-DIMENSIONAL CAROTID ULTRASOUND

2015 ◽  
Vol 31 (10) ◽  
pp. S230-S231
Author(s):  
H. Kalashyan ◽  
M. Saqqur ◽  
A. Shuaib ◽  
H. Romanchuk ◽  
T. Jeerakathil ◽  
...  
2020 ◽  
Vol 22 (12) ◽  
pp. 2257-2266
Author(s):  
Dong‐Hwa Lee ◽  
Eun Ju Chun ◽  
Ji Hye Moon ◽  
Han Mi Yun ◽  
Soo Lim

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
G P Perea Gabriel ◽  
M Corneli ◽  
G Daquarti ◽  
A Meretta ◽  
D Rosa ◽  
...  

Abstract Background Atherosclerosis is a dynamic process, in which the characteristics of the plaques evaluated by imaging methods could represent the degree of inflamatory activity of the disease. Purpose Assess the value of the coronary calcium score in the changes of echogenicity of carotid plaques in a population with low-intermediate cardiovascular risk. Methods Patients with no cardiovascular history and low and intermediate Framingham risk score were evaluated. Patients attended at our institute for a preventive cardiovascular control between January 2012 and April 2013, and then a subsequent follow-up was made until January 2019. They were screened for coronary calcium scoring (CCS) and carotid plaque by ultrasound at first visit. Then the changes of carotid atherosclerotic disease were evaluated through new carotid ultrasound exam at follow up. A carotid artery plaque was defined as a localized protrusion of the vessel wall, which 1) extended into the lumen ≥ 1.5 mm, or 2) had a thickness exceeding the intima-media thickness (IMT) of the adjacent portion of the vessel wall by >50%. Plaque morphology was defined in terms of its echogenicity. Results 121 patients that have carotid atherosclerotic disease at first carotid ultrasound exam were included. The mean age was 61 ± 9 years, 72 (59%) male patients. Cardiovascular risk factors: hypertension: 68 (56%), dyslipidemia: 46 (38%), sedentary lifestyle: 24 (20%), overweight: 17 (14%), smoking: 29 (24%) and diabetes: 15 (12%). Median distribution of CCS was 192 (percentile distribution 25-75%: 8 – 224) Agatston units. Medium follow-up: 5 ± 1 year. At first ultrasonography study, 47 patients (39%) presented hypoechoic plaques, 61 patients (50%) isoechoic plaques and hyperechoic plaques in 13 patients (11%). After the follow-up, the distribution of the plates according to their sonographic characteristics was: hypoechoic plaques in 23 patients (19%), isoechoic plaques in 55 patients (45%) and hyperechoic plaques in 42 patients (36%). The incidence of the progression of sonographic changes of the carotid plaques varies according to CCS: 0-100:29%, 101-400: 54%, >401:53% (p < 0,001) Figure 1. The value of CCS was associated with the progression of carotid atherosclerotic plaque regardless of the use of statins and angiotensin-converting enzyme inhibitors or angiotensin 2 receptor blockers (Cox model p <0.001). Conclusions This study shows that there is an association between coronary calcium score and progression of carotid disease. Even in populations with low and intermediate cardiovascular risk, the higher the severity of the calcium score, the greater changes in the structure of the carotid plaque manifested in our work as changes in the echogenicity; regardless of the use of statins. These findings could be useful to assess the progression of atherosclerotic disease at a median follow up. Abstract 436 Figure. folow up


2017 ◽  
Vol 33 (3) ◽  
pp. 412.e1-412.e3
Author(s):  
Hayrapet Kalashyan ◽  
Maher Saqqur ◽  
Harald Becher ◽  
Cian O'Kelly ◽  
Helen Romanchuk ◽  
...  

2007 ◽  
Vol 34 (4) ◽  
pp. 1496-1505 ◽  
Author(s):  
Anthony Landry ◽  
Craig Ainsworth ◽  
Chris Blake ◽  
J. David Spence ◽  
Aaron Fenster

2018 ◽  
Vol 8 (1) ◽  
pp. 32 ◽  
Author(s):  
Maria Noflatscher ◽  
Michael Schreinlechner ◽  
Philip Sommer ◽  
Julia Kerschbaum ◽  
Katharina Berggren ◽  
...  

Background: Atherosclerosis is a systemic multifocal disease with a preference for the branching points of the arteries. In this study, we quantitatively measured carotid and femoral plaque volume in subjects with cardiovascular risk factors (CVRF) and/or established atherosclerotic disease using a 3D ultrasound technique. Methods: In this prospective, single-centre study, we included 404 patients (median age 64; 56.9% men) with at least one CVRF or established cardiovascular disease. Plaque volume was measured using 3D ultrasound equipped with an automated software. Results: We found a strong correlation of plaque volume with CVRF and the number of vascular beds involved. The strongest associations with total and femoral plaque volume were noted for smoking, hypertension, age, as well as for the presence of peripheral arterial occlusive disease (p <0.05). Carotid plaque volume was best predicted by hyperlipidaemia, hypertension, age, as well as the presence of cerebrovascular disease and coronary artery disease (p <0.05). Conclusion: We conclude that smoking appears to be associated with total and femoral plaque volume, whereas hyperlipidaemia seems to be associated with carotid plaque volume. Measurement of 3D plaque volume is a practical and reproducible technique with the potential to become an additional screening tool in cardiovascular risk stratification.


2017 ◽  
Vol 65 (5) ◽  
pp. 1407-1417 ◽  
Author(s):  
Amir A. Khan ◽  
Christian Koudelka ◽  
Carly Goldstein ◽  
Limin Zhao ◽  
John Yokemick ◽  
...  

2021 ◽  
Vol 10 (21) ◽  
pp. 4975
Author(s):  
Iván Ferraz-Amaro ◽  
Alfonso Corrales ◽  
Belén Atienza-Mateo ◽  
Nuria Vegas-Revenga ◽  
Diana Prieto-Peña ◽  
...  

Patients with rheumatoid arthritis (RA) have a higher incidence of subclinical atherosclerosis and cardiovascular (CV) disease. It is postulated that the appearance of accelerated atherosclerosis in these patients is a consequence of the inflammation present in the disease. In this study, we aim to determine if baseline disease activity in patients with RA predicts the future development of carotid plaque. A set of consecutive RA patients without a history of CV events, cancer or chronic kidney disease, who did not show carotid plaque in a carotid ultrasound assessment, were prospectively followed up for at least 5 years. At the time of recruitment, CV risk factors and disease-related data, including disease activity scores, were assessed. At the end of the follow-up, a carotid ultrasound was repeated and patients were divided into two groups; those who developed carotid plaque, and those who did not. A multivariable regression analysis was performed to define the predictors for the development of carotid plaque. One hundred and sixty patients with RA were followed up for an average of 6 ± 1 years. After this time, 66 (41%) of the patients had developed carotid plaque, and 94 (59%) did not. Patients with carotid plaque were significantly older (47 ± 13 vs. 55 ± 9 years, p < 0.001) at baseline, were more frequently diabetic (0% vs. 6%, p = 0.028), and had higher total cholesterol (197 ± 36 vs. 214 ± 40 mg/dL, p = 0.004) and LDL cholesterol (114 ± 35 vs. 126 ± 35 mg/dL, p = 0.037) at the beginning of the study. After multivariable adjustment, patients who were in the moderate and high disease activity (DAS28-CRP) categories displayed a higher odds ratio for the appearance of carotid plaque (OR 2.26 [95% CI 1.02–5.00], p = 0.044) compared to those in the DAS-28-CRP remission category. Remarkably, when patients were divided in patients within the low-risk SCORE category, and patients included in the remaining SCORE categories (moderate, high and very high), the relation between DAS28-CRP and the development of carotid plaque was only significant in the low-risk SCORE category. In conclusion, disease activity predicts the future development of subclinical atherosclerosis in patients with RA.


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