Structure and dynamics of the surfactant molecules in dodecyltrimethylammonium·poly(α,l-glutamate) self-assembled complexes

2004 ◽  
Vol 305 (1-3) ◽  
pp. 85-93 ◽  
Author(s):  
David Zanuy ◽  
Jordi Casanovas ◽  
Carlos Alemán
Keyword(s):  
Structure And Dynamics ◽  
Assembled Complexes ◽  
Self Assembled

Synthesis and mesomorphism of ionic self-assembled complexes of anthraquinones

2017 ◽  
Vol 44 (14-15) ◽  
pp. 2311-2320 ◽  
Author(s):  
K. Swamynathan ◽  
V. A. Raghunathan ◽  
Sandeep Kumar
Keyword(s):  
Assembled Complexes ◽  
Self Assembled

scholarly journals MrDNA: a multi-resolution model for predicting the structure and dynamics of DNA systems

2020 ◽  
Vol 48 (9) ◽  
pp. 5135-5146 ◽  
Author(s):  
Christopher Maffeo ◽  
Aleksei Aksimentiev
Keyword(s):  
Self Assembly ◽  
De Novo ◽  
Dna Nanotechnology ◽  
Equilibrium Structure ◽  
Molecular Graphics ◽  
Structure And Dynamics ◽  
Self Assembled ◽  
Actual Shape ◽  
And Function ◽  
Assembly Principles

Abstract Although the field of structural DNA nanotechnology has been advancing with an astonishing pace, de novo design of complex 3D nanostructures and functional devices remains a laborious and time-consuming process. One reason for that is the need for multiple cycles of experimental characterization to elucidate the effect of design choices on the actual shape and function of the self-assembled objects. Here, we demonstrate a multi-resolution simulation framework, mrdna, that, in 30 min or less, can produce an atomistic-resolution structure of a self-assembled DNA nanosystem. We demonstrate fidelity of our mrdna framework through direct comparison of the simulation results with the results of cryo-electron microscopy (cryo-EM) reconstruction of multiple 3D DNA origami objects. Furthermore, we show that our approach can characterize an ensemble of conformations adopted by dynamic DNA nanostructures, the equilibrium structure and dynamics of DNA objects constructed using off-lattice self-assembly principles, i.e. wireframe DNA objects, and to study the properties of DNA objects under a variety of environmental conditions, such as applied electric field. Implemented as an open source Python package, our framework can be extended by the community and integrated with DNA design and molecular graphics tools.

scholarly journals Efficient Gene Silencing by Self-Assembled Complexes of siRNA and Symmetrical Fatty Acid Amides of Spermine

Pharmaceutics ◽  
2011 ◽  
Vol 3 (2) ◽  
pp. 125-140 ◽  
Author(s):  
Abdelkader A. Metwally ◽  
Charareh Pourzand ◽  
Ian S. Blagbrough
Keyword(s):  
Fatty Acid ◽  
Gene Silencing ◽  
Fatty Acid Amides ◽  
Efficient Gene ◽  
Assembled Complexes ◽  
Self Assembled
Sign in / Sign up

Export Citation Format

Share Document