Short-term Use of Ginkgo-Flavone Glycosides Increase Risk of Gastrointestinal Bleeding: A Nationwide Population-based Case-Crossover Study

2017 ◽  
Vol 15 (1) ◽  
pp. e45-e46
Author(s):  
Wen-Chieh Wu ◽  
Kuan Chieh Fang ◽  
Bi-Ling Yang ◽  
Shun-Ku Lin ◽  
Hisao-Yun Hu
2015 ◽  
Vol 42 (5) ◽  
pp. 599-606 ◽  
Author(s):  
C.-L. Tseng ◽  
Y.-T. Chen ◽  
C.-J. Huang ◽  
J.-C. Luo ◽  
Y.-L. Peng ◽  
...  

2018 ◽  
Vol 167 ◽  
pp. 544-549 ◽  
Author(s):  
Giovenale Moirano ◽  
Antonio Gasparrini ◽  
Fiorella Acquaotta ◽  
Simona Fratianni ◽  
Franco Merletti ◽  
...  

TH Open ◽  
2019 ◽  
Vol 03 (01) ◽  
pp. e50-e57
Author(s):  
Vânia Morelli ◽  
Joakim Sejrup ◽  
Birgit Småbrekke ◽  
Ludvig Rinde ◽  
Gro Grimnes ◽  
...  

AbstractStroke is associated with a short-term increased risk of subsequent venous thromboembolism (VTE). It is unclear to what extent this association is mediated by stroke-related complications that are potential triggers for VTE, such as immobilization and infection. We aimed to investigate the role of acute stroke as a trigger for incident VTE while taking other concomitant VTE triggers into account. We conducted a population-based case-crossover study with 707 VTE patients. Triggers were registered during the 90 days before a VTE event (hazard period) and in four preceding 90-day control periods. Conditional logistic regression was used to estimate odds ratios with 95% confidence intervals (CIs) for VTE according to triggers. Stroke was registered in 30 of the 707 (4.2%) hazard periods and in 6 of the 2,828 (0.2%) control periods, resulting in a high risk of VTE, with odds ratios of 20.0 (95% CI: 8.3–48.1). After adjustments for immobilization and infection, odds ratios for VTE conferred by stroke were attenuated to 6.0 (95% CI: 1.6–22.1), and further to 4.0 (95% CI: 1.1–14.2) when other triggers (major surgery, red blood cell transfusion, trauma, and central venous catheter) were added to the regression model. A mediation analysis revealed that 67.8% of the total effect of stroke on VTE risk could be mediated through immobilization and infection. Analyses restricted to ischemic stroke yielded similar results. In conclusion, acute stroke was a trigger for VTE, and the association between stroke and VTE risk appeared to be largely mediated by immobilization and infection.


2017 ◽  
Vol 2 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Gro Grimnes ◽  
Trond Isaksen ◽  
Y. I. G. Vladimir Tichelaar ◽  
Sigrid K. Braekkan ◽  
John-Bjarne Hansen

2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Simon Thornley ◽  
Bridget Kool ◽  
Elizabeth Robinson ◽  
Roger Marshall ◽  
Gordon S Smith ◽  
...  

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