scholarly journals Stem Cells: A Renaissance in Human Biology Research

Cell ◽  
2016 ◽  
Vol 165 (7) ◽  
pp. 1572-1585 ◽  
Author(s):  
Jun Wu ◽  
Juan Carlos Izpisua Belmonte
Keyword(s):  
Stem Cells ◽  
Human Biology ◽  
Biology Research

Applying the community partnership approach to human biology research

2014 ◽  
Vol 27 (1) ◽  
pp. 6-15 ◽  
Author(s):  
Julia Ravenscroft ◽  
Lawrence M. Schell ◽  
Tewentahawih′tha′ Cole
Keyword(s):  
Human Biology ◽  
Community Partnership ◽  
Partnership Approach ◽  
Biology Research

After Theranos: Using point‐of‐care testing to advance measures of health biomarkers in human biology research

2021 ◽  
Author(s):  
Theresa E. Gildner ◽  
Geeta N. Eick ◽  
Alaina L. Schneider ◽  
Felicia C. Madimenos ◽  
J. Josh Snodgrass
Keyword(s):  
Point Of Care ◽  
Human Biology ◽  
Point Of Care Testing ◽  
Biology Research

scholarly journals Stem cells: the new “model organism”

2017 ◽  
Vol 28 (11) ◽  
pp. 1409-1411 ◽  
Author(s):  
David G. Drubin ◽  
Anthony A. Hyman
Keyword(s):  
Stem Cells ◽  
Tissue Culture ◽  
Stem Cell ◽  
Human Tissue ◽  
Cell Biology ◽  
Physiological Function ◽  
Model Organism ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Biology Research

Human tissue culture cells have long been a staple of molecular and cell biology research. However, although these cells are derived from humans, they have often lost considerable aspects of natural physiological function. Here we argue that combined advances in genome editing, stem cell production, and organoid derivation from stem cells represent a revolution in cell biology. These advances have important ramifications for the study of basic cell biology mechanisms, as well as for the ways in which discoveries in mechanisms are translated into understanding of disease.

Properties and uses of embryonic stem cells: prospects for application to human biology and gene therapy

1998 ◽  
Vol 10 (1) ◽  
pp. 31 ◽  
Author(s):  
P. D. Rathjen ◽  
J. Lake ◽  
L. M. Whyatt ◽  
M. D. Bettess ◽  
J. Rathjen
Keyword(s):  
Stem Cells ◽  
Gene Therapy ◽  
Embryonic Stem Cells ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Cell Types ◽  
Human Biology ◽  
Pluripotent Cell ◽  
Cell Specification

Embryonic stem cells are pluripotent cells derived from the early mouse embryo that can be propagated stably in the undifferentiated state in vitro. They retain the ability to differentiate into all cell types found in an embryonic and adult mouse in vivo, and can be induced to differentiate into many cell types in vitro. Exploitation of ES cell technology for the creation of mice bearing predetermined genetic alterations has received widespread attention because of the sophistication that it brings to the study of gene function in mammals. Analysis of cell differentiation in vitro has also been of value, leading to the identification of novel bioactive factors and the elucidation of cell specification mechanisms. In this paper, we summarise the features of pluripotent cell lines and their applications, foreshadowing the impact that these systems may have on human biology. While the isolation of definitive human pluripotent cell lines has not yet been achieved, potential applications for these cells in the study of human biology, particularly cell specification, can be envisaged. Of particular interest is the possibility that human embryonic stem cells with properties similar to mouse embryonic stem cells might provide a generic system for gene therapy.

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