scholarly journals SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

Cell ◽  
2008 ◽  
Vol 134 (2) ◽  
pp. 353-364 ◽  
Author(s):  
Marcus Krüger ◽  
Markus Moser ◽  
Siegfried Ussar ◽  
Ingo Thievessen ◽  
Christian A. Luber ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Quantitative Proteomics ◽  
Cell Function ◽  
Essential Factor

THE NUMBER OF RED BLOOD CELLS IN THE ISLETS OF LANGERHANS AS AN INDEX OF THE B CELL ACTIVITY

1960 ◽  
Vol XXXIV (IV) ◽  
pp. 611-618 ◽  
Author(s):  
Claes Hellerström ◽  
Sighild Westman ◽  
Ulla Zachrisson ◽  
Bo Hellman
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
B Cell ◽  
Islets Of Langerhans ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Cell Function ◽  
Cell Activity ◽  
Control Group ◽  
Cell Content

ABSTRACT The number of red blood cells in the islets of Langerhans has been considered as a useful index of the insulin synthesis, i. e. of the functional state of the B cells of the islets. It was found, however, that in starved rats which had only received water orally, the red blood cell content within the islets increased both absolutely as well as relatively to that in the exocrine parenchyma at the same time as the decrease in the B cell function as estimated by caryometry. There was a marked correlation, both in the control group and in the starved rats, between the red blood cell concentration in the exocrine and endocrine parts of the pancreas. The extent to which a rise in the functional activity of the A cells might have contributed to the increased content of red blood cells in the islets during starvation is discussed.

Hypoxia, Hormones, and Red Blood Cell Function in Chick Embryos

Physiology ◽  
2003 ◽  
Vol 18 (2) ◽  
pp. 77-82 ◽  
Author(s):  
Stefanie Dragon ◽  
Rosemarie Baumann
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Adrenergic Receptor ◽  
Cell Function ◽  
Oxygen Affinity ◽  
Terminal Differentiation ◽  
Receptor Activation ◽  
Avian Embryos ◽  
Hypoxic Conditions ◽  
Hemoglobin Oxygen Affinity

The red blood cell function of avian embryos is regulated by cAMP. Adenosine A2A and β-adrenergic receptor activation during hypoxic conditions cause changes in the hemoglobin oxygen affinity and CO2 transport. Furthermore, experimental evidence suggests a general involvement of cAMP in terminal differentiation of avian erythroblasts.

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