Radiotheranostics with radiolanthanides: Design, development strategies, and medical applications

2019 ◽  
Vol 383 ◽  
pp. 104-131 ◽  
Author(s):  
Kenji Mishiro ◽  
Hirofumi Hanaoka ◽  
Aiko Yamaguchi ◽  
Kazuma Ogawa
Author(s):  
Olivier Piccin ◽  
Nitish Kumar ◽  
Laurence Meylheuc ◽  
Laurent Barbé ◽  
Bernard Bayle

This paper presents the development of NGDs (needle grasping devices) capable of handling elongated objects such as surgical needles. After describing the main demands of medical needle-based procedures, a requirement list for a typical NGD is presented. Some solution principles for a grasping device are generated, combined and then classified to obtain a set of principle variant solutions. The design study of some of these variant solutions is then developed and a discussion on two device candidates constructed using either interconnected rigid bodies or compliant parts will be presented. The mechanical behavior of the compliant mechanism acting on a needle barrel is simulated with a FEM analysis including the model of non-linearities induced by large deformations and the contact between the needle and the grasping device. Functional prototypes of both NGDs have been constructed and a first experimental assessment of their service capability is finally exposed.


2014 ◽  
Author(s):  
V. Scott H. Solberg ◽  
Eleanor Castine ◽  
Zi Chen ◽  
Sean Flanagan ◽  
Taryn Hargrove ◽  
...  

1976 ◽  
Vol 15 (02) ◽  
pp. 69-74
Author(s):  
M. Goldberg ◽  
B. Doyon

This paper describes a general data base management package, devoted to medical applications. SARI is a user-oriented system, able to take into account applications very different by their nature, structure, size, operating procedures and general objectives, without any specific programming. It can be used in conversational mode by users with no previous knowledge of computers, such as physicians or medical clerks.As medical data are often personal data, the privacy problem is emphasized and a satisfactory solution implemented in SARI.The basic principles of the data base and program organization are described ; specific efforts have been made in order to increase compactness and to make maintenance easy.Several medical applications are now operational with SARI. The next steps will mainly consist in the implementation of highly sophisticated functions.


2019 ◽  
Vol 3 (1) ◽  
pp. 70-80
Author(s):  
Sri Ayu Harani Tanjung ◽  
Yuli Amalia

Bahan ajar dikembangkan berdasarkan karakteristik siswa, sehingga kompetensi yang ditetapkan dapat dicapai. Secara umum kemampuan pemecahan masalah siswa masih sangat rendah, siswa belum bisa memahami soal, sehingga terkendala dalam menentukan model penyelesaian soal matematika. Penelitian ini bertujuan untuk mendeskripsikan kevalidan, keefektifan, dan respon siswa terhadap bahan ajar berbasis Problem Based Learning berkemampuan pemecahan masalah yang dikembangkan. Penelitian ini merupakan penelitian pengembangan dengan menggunakan model ADDIE yaitu Analysis, Design, Development, Implementation, dan Evaluation. Subjek Penelitan dalam penelitian ini adalah siswa SMA Negeri 1 Meureubo kelas X Mia2 sebanyak 23 siswa. Instrumen penelitian berupa lembar validasi, angket respon siswa, dan tes. Dari hasil uji coba, pada uji coba I dan II diperoleh bahan ajar berbasis Problem Based Learning yang dikembangkan efektif ditinjau dari 70% siswa yang mengikuti tes kemampuan pemecahan masalah memperoleh nilai minimal 75 dan tercapainya ketuntasan belajar tes kemampuan pemecahan masalah  75% dan respon positif siswa terhadap bahan ajar berbasis Problem Based Learning untuk kemampuan pemecahan masalah yang dikembangkan. Teaching materials are developed based on the characteristics of students, so that the specified competencies can be achieved. In general, students' problem solving abilities are still very low, students have not been able to understand the problem, so it is constrained in determining the mathematical problem solving model. This study aims to describe the validity, effectiveness, and response of students to Problem Based Learning-based teaching materials that are problem-solving skills developed. This research is a development research using ADDIE models namely Analysis, Design, Development, Implementation, and Evaluation. The research subjects in this study were 23 students of Meureubo High School 1 in class Mia2 as many as 23 students. The research instruments were validation sheets, student response questionnaires, and tests. From the results of the trials, in the first and second trials obtained teaching materials based on Problem Based Learning that were developed effectively in terms of 70% of students taking the test of problem solving skills obtained a minimum score of 75 and achievement of learning completeness 75% problem solving ability tests and positive responses for Problem Based Learning based teaching materials for problem solving abilities developed.


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